Complications after postinoration. Postinor: consequences. Questions Frequent use of postinor

Postinor, and its analogues Escapel, Microlut, Eskinor F, are a means of contraception only in emergency cases, that is, for life-threatening reasons, such as rape, rupture of a condom during sexual intercourse.

Why can't it be used on an ongoing basis? This drug in developed countries can only be purchased with a prescription, unlike in Russia, since Postinor has serious side effects.

However, some women use these drugs quite often, without consulting a gynecologist and not knowing about the consequences, complications, side effects of Postinor and its analogues. To understand what effect these drugs have on the body, you should know the mechanism of their action.

Mechanism of action of Postinor

Postinor causes a lot of side effects and its use is possible only in extreme cases. During puberty and for women planning to have children in the future, its use is not advisable, since this can lead to hormonal imbalance in a woman and cause infertility in the future.

Postinor and its analogues are intended only for emergency prevention of pregnancy. The active ingredient of the drug is levonorgestrel, of which there is 0.75 mg in one tablet, which is considered a lethal dose. In low-dose oral contraceptives, for example, this dose of levonorgestrel is contained in 20 tablets. The Postinor package contains 2 tablets, which are taken 12 hours apart for 72 hours after unprotected sexual intercourse. The mechanism of action of levonorgestrel is as follows:

• a drug blocks ovulation- prevents a mature egg from leaving the ovary
• when ovulation has already occurred, Postinor prevents implantation of the fertilized egg in the uterine cavity - in this case it essentially has an abortifacient effect
• leads to a change in cervical mucus, it becomes thicker, which interferes with the penetration of sperm into the uterine cavity.

When the implantation of a fertilized egg into the wall of the uterus has already occurred, the drug becomes ineffective, since all gestagens have the property of suppressing the motor activity of the uterine muscles.

Contraindications

The use of Postinor is contraindicated for use in the following cases:

• liver dysfunction, severe liver disease
• teenage girls under 16 years old
• During lactation, the drug passes into breast milk, so it is contraindicated during breastfeeding.
• with uterine bleeding of unknown origin
• for individual intolerance
• for herpetic infections and other infectious diseases of the genitourinary system
• in diseases associated with enzymatic deficiency - impaired absorption of glucose, galactose (lactase deficiency)
• for malignant neoplasms of any location
• with a genetic predisposition to thrombosis

Use with caution for ulcerative lesions of the gastrointestinal tract, diseases of the biliary tract.

Side effects of Postinor

Any medications have side effects, and Postinor is a powerful hormonal drug, which in some cases can become a trigger for the development of serious health problems in a woman. Therefore, in developed countries this drug is available only by prescription and is considered an unsafe method of contraception. Side effects of Postinor are as follows:

• Intestinal dysfunction - diarrhea
• Digestive disorders - vomiting, diarrhea
• Headache, dizziness
• Intermenstrual bleeding
• Breast tension
• Flu-like symptoms
• Weakness, lethargy

If you experience any side effects from taking Postinor or other unusual signs of illness, you should consult a doctor.

Side effects from the reproductive system, impact on the woman’s reproductive function in the future

Considering that 1 tablet contains a huge amount of active substance, a real hormonal imbalance occurs in a woman’s body after taking Postinor. The instructions for the drug say that it is not recommended to use it more than 4 times a year. But some women often neglect these recommendations and take it uncontrollably, sometimes even several times per menstrual cycle, which is very dangerous and prohibited.

Since Postinor should be taken when there is a high probability of pregnancy (ovulation period) - at this time the mucous membrane of the uterus has not yet matured, which leads to dysfunction of the ovaries, and then they produce either less or more hormones. And even with a one-time use of the drug, a certain time is required (in each case individually) to restore ovarian function.

Therefore, if a woman with existing menstrual irregularities:

• irregular menstruation
• teenagers under 16 years old

If you take the drug even once, such disruptions can be permanent and cause infertility in the future.

The influence of this hormonal drug, especially on an ongoing basis, leads to the fact that the function of the ovaries begins to fade, become depleted, and the production of hormones gradually becomes less and less. This causes irregularities in the menstrual cycle and can affect a woman's reproductive ability. In some cases, taking the drug leads to amenorrhea (lack of menstruation) and, as a result, persistent infertility. Even a timely visit to a gynecologist in such cases cannot guarantee the successful restoration of the normal menstrual cycle and the likelihood of pregnancy.

If a woman has periodic uterine bleeding, taking Postinor and its analogues can intensify it and lead to the need for emergency medical care, so in such cases taking the drug is unacceptable. Also, one of the side effects of Postinor is engorgement and soreness of the mammary glands, and the appearance of discharge from the nipples.

Other side effects of Postinor

In addition to disorders associated with hormonal shock, the effects of Postinor and Escapel, if taken incorrectly, can have other consequences, such as, for example, the formation of blood clots in blood vessels. This side effect can mainly occur in women with bleeding disorders, but even a seemingly healthy woman has this risk (see video - documentary).

After repeated use of maximum doses of hormones, blood clotting ability increases and the risk of blood clots in blood vessels increases. When the lumens of blood vessels are partially blocked, there is a reduction in blood flow to organs and tissues and, as the most extreme pathology, blockage of blood vessels (the occurrence of pulmonary thromboembolism). When blood vessels in the heart and brain become blocked, a stroke or instant death may occur.

If a woman does not have any problems with the menstrual cycle, side effects of Postinor occur quite rarely. But other ailments may appear - pain in the lower abdomen, nausea, diarrhea, headaches, swelling. Due to frequent use of Postinor, disturbances in fat and carbohydrate metabolism may occur, causing a decrease or increase in body weight, and suppression can lead to changes in male-type hair growth or changes in the contours of the figure.

Every woman who cares about her health should watch this video before deciding to take any oral contraceptives (even low-dose ones). This is especially true for young girls who want to have children in the future.

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

Elena asks:

Hello! My name is Lena, I'm 22 years old. We had sexual intercourse on July 25 and the condom broke. About an hour later I took a postinor tablet, the next one 17 hours later. Menstruation is constant, cycle is 28 days. Your period should start on July 27th. Please tell me how much this drug will help me, I was a couple of hours late with the second pill. And is pregnancy possible during these periods, do these seem to be safe days. Thanks for the help!!!

If sperm enters the female genital tract, pregnancy is possible. Prem of the drug Postinor significantly reduces the likelihood of pregnancy. Taking the first pill as early as possible is important in emergency contraception.

Katya asks:

Hello! I took Postinor 25 hours after unprotected PA, the next pill 12 hours later, according to the instructions. For the third day now I have not observed any consequences, only yellowish discharge, similar to thrush. Tell me, please, is it possible that these are signs of pregnancy??
Thank you!

If on the 5th-7th day of taking the drug, intermenstrual bleeding does not begin, you must consult a gynecologist and donate blood for hCG to rule out pregnancy.

Karina asks:

Hello! I took Postinor after 36 hours, and after 5 days the effect will begin? If there is no pregnancy, will there still be bleeding?

Postinor begins to act immediately after using the tablet (after its dissolution and absorption in the intestines). Bleeding, which should appear 5-6 days after using this drug, indicates the highest possible contraceptive effect and the exact absence of pregnancy. If there is no bleeding at all or it occurs later, you will need to undergo an examination by a gynecologist to rule out pregnancy. You can read more about the drug Postinor and its effect on the body in our section: Postinor.

Karina asks:

thanks for the answer! I have another problem ((in general, I drank as expected, after 5 hours my period started, my stomach hurt for 3 days, yesterday the tingling sensation in the lower abdomen began, in the evening it intensified, it hurts to press on the lower abdomen, today it’s the same, only it hurts less .could this be from postinor?

The listed symptoms may be associated with taking the hormonal contraceptive Postinor, so there is no need to worry. As a rule, these symptoms go away on their own; no specific measures are required. More information about this can be found in the section: Hormonal contraceptives

Anya asks:

Hello! Immediately after unprotected intercourse, I drank a glass of milk with iodine, after which within 24 hours I took the first postinor tablet (the second as per instructions), but after 5 days no changes occurred, is there a possibility that I am pregnant?

As a rule, bleeding after Postinor begins 6 days after taking the last pill. If it is absent, then it is necessary to exclude the possibility of pregnancy. To do this, I recommend that you do a blood test for hCG 7-10 days after sexual intercourse. More information on this issue can be found in the section: Analysis for hCG

Maria asks:

I had sexual intercourse for two days in a row, and both times I didn’t use protection, everything happened to me, 48 hours after the first time, I took Postinor, but it turned out that I got pregnant anyway, could this be?

Unfortunately, this situation is possible, since the drug Postinor is not 100% effective. In addition, the timing of taking Postinor is also important - the longer the interval from sexual intercourse to taking Postinor, the less effective it is. You can get more information on this issue in the thematic section of our website: Postinor

Rita asks:

the condom broke, it broke, I drank postinor after 8 hours, then follow the instructions. I have a question: my period should come in 1-2 days, how can I tell if my period comes, did the postinor work?

If you begin to have menstrual bleeding, pregnancy can be completely ruled out and this will mean that the drug has worked. Read more about the action of the drug Postinor in a series of articles by clicking on the link: Postinor.

Victoria asks:

Tell me, within 12 hours after intercourse I took Postinor, then a second pill, all on time. My period began (as it should be according to the cycle, it coincided) 6 days after the act and taking the postinor. after 2 weeks, menstruation began again, or rather spotting, often black. 4 days later I got my heavy period. Can you tell me if this could be a consequence of taking Postinor and whether it will go back to normal in the next month or if I need to see a doctor urgently?

These bleedings are associated with taking the hormonal contraceptive Postinor. In such cases, there is no need to do anything; the menstrual cycle will resume on its own. I recommend that you use barrier methods of contraception. You can get more detailed information on the issue you are interested in in the corresponding section of our website by clicking on the following link: Postinor

Damira asks:

Hello. On February 1st I had sexual intercourse and the condom broke within an hour. I took 1 postinor tablet within an hour, then 12 hours later a second one. There were no side effects, on February 3rd the temperature appeared, on the 4th and 5th it began to subside. Nothing happens, it scares me. Menstruation should arrive around February 15. What should I do?

As a rule, after taking the drug Postinor, bleeding begins on the 6th day, but in some cases it may be later. Considering that you took the drug correctly, there is no need to worry, there is no need to do anything now. You can get more detailed information on the issue you are interested in in the corresponding section of our website by clicking on the following link: Postinor. You can also get additional information in the following sections of our website: Probability of getting pregnant, Menstrual cycle and menstruation

Marina asks:

Hello! I am 40 years old. Yesterday at 19.00 I had unprotected sexual intercourse, the very middle of the cycle, a dangerous week. This morning at 10.00 I took the first Postinor tablet, 15 hours have passed since PA. My lower abdomen hurt, my heart rate increased, in general, all the signs and effects of the drug. I'm waiting for the bleeding to start. My question is: Can I start taking Tri-Regol on the first day of bleeding after taking Postinor?

In this situation, you should take the second Postinor tablet after 12 hours, after which, as a rule, menstrual-like bleeding begins after 6 days. It is not the beginning of menstruation, so there is no need to take Tri-Regol - wait until your next menstruation and from the first day of the cycle you can use cyclic hormonal contraceptives if they are prescribed to you by your gynecologist.

You can obtain additional information on the issue you are interested in in the appropriate section of our website by clicking on the following link: Postinor, as well as in the section: Emergency contraception Hormonal contraceptive Tri-Regol: instructions for use and in the series of articles: Hormonal contraceptives

Valentina asks:

I had my period on June 18, I had an unprotected PA on June 2, but my partner didn’t cum in me, I believe him.
About 10 hours later I drank Postinor, and 12 hours later I took another one, just in case.
Can pregnancy be ruled out already?
Or what should I expect?

In this situation, there was no need to use emergency contraception if there was no ejaculation into the vagina. Taking Postinor excludes pregnancy, so there is no reason to worry. Next, I recommend that you use barrier methods of contraception. You can get more detailed information on the issue you are interested in in the corresponding section of our website by clicking on the following link: Postinor and in the series of articles: Emergency contraception. You can also get additional information in the following section of our website: Probability of getting pregnant

Marina asks:

Hello, I took Postinor 40 hours later, 4 days have already passed and dark visions appeared and my stomach hurts constantly, I had sex 2 days before my period, tell me if the drug will help and what is the likelihood of pregnancy?!

The possibility of pregnancy is excluded if you take the hormonal contraceptive Postinor in a timely manner. The presence of bloody discharge confirms that pregnancy has not occurred, so there is no reason to worry. You can get more detailed information on the issue you are interested in in the corresponding section of our website by clicking on the following link: Postinor and in the series of articles: Emergency contraception. You can also get additional information in the following section of our website: Probability of getting pregnant

Elena asks:

Unprotected intercourse, after 3 hours I took 2 Postinor tablets at once (I didn’t read the instructions, unfortunately), then I had sexual intercourse within 24 hours. 5 days have passed - slightly bloody discharge. Question: is it a long-acting drug?

The emergency contraceptive Postinor, according to the instructions, must be used according to the scheme - 2 tablets with an interval of 12 hours, and the contraceptive effect extends to sexual intercourse that occurred before taking Postinor. The presence of bloody discharge indicates the absence of pregnancy, so there is no need to worry. We recommend that you do not panic and continue to use barrier methods of contraception, and if you have regular sexual activity, personally consult with your gynecologist to select a reliable contraceptive.

You can get more detailed information on the issue you are interested in in the corresponding section of our website by clicking on the following link: Postinor and in the series of articles: Emergency contraception. You can also get additional information in the following section of our website: Probability of getting pregnant

Elena asks:

The condom broke in the middle of the menstrual cycle. After 4 hours I took the first postinor tablet, and after 12 hours the second. There are no sensations, today is the 4th day after unprotected intercourse, there is no discharge. Did Postinor work?

As a rule, after taking the hormonal contraceptive Postinor, bleeding is observed after 6 days, but in some cases it may be absent, which, however, does not give grounds to judge the lack of effect from the use of this emergency contraceptive. Considering that the drug was taken in a timely manner, there is no reason to panic.

Elena asks:

My partner and I had an unprotected PA on the 8th. He didn’t cum inside me, after about 25 hours I took the first pill and after 12 hours I took the second. Tell me please, should it help? How soon should my period start?

If there is no ejaculation into the vagina during sexual intercourse, then there is no chance of pregnancy. In this situation, there was no need to use the emergency contraception Postinor. After taking this medication, bleeding usually begins after 6 days, and the next menstruation may come late.

Before delving into the question of what the consequences of postinor are, let’s consider the purpose and principle of action of this drug.

Purpose and principle of operation

So, postinor is a means of emergency or, scientifically, postcoital contraception. This drug helps prevent unwanted pregnancy after sexual intercourse. They rarely think about the consequences of taking it, since it has no analogues, and therefore for many it becomes the only way out. And there is something to think about.

Postinor contains a large amount of the hormone levonorgestrel, which has a strong effect on the woman’s body. Levonorgestrel strikes in three directions at once:

• It prevents ovulation, that is, it inhibits the process of egg maturation. An immature egg cannot be fertilized, and therefore pregnancy cannot occur.
• Affects sperm, interfering with fertilization.
• Affects the endometrium. Levonorgestrel can change the internal structure of the uterus, thereby preventing an already fertilized egg from attaching to its walls - medical abortion.

Thus, the effect of this contraceptive is to disrupt the normal functioning of the uterus and ovaries, which cannot pass without consequences for the female body.

Admission rules

As mentioned above, Postinor is a strong hormonal drug and can only be taken as prescribed by a doctor. This drug has a number of contraindications that should never be ignored. It should not be taken by teenagers under 16 years of age, as it can cause hormonal disruption in a still developing body and lead to serious consequences. It is also not recommended for use in cases of liver failure, diseases of the biliary tract, individual increased reaction to the components of the drug, during lactation, etc.

You must take emergency contraception strictly according to the instructions: the first pill should be taken as soon as possible after unprotected intercourse, and the second no earlier than 12 hours and no later than 15 hours after taking the first. It is important to take both pills before the third day after sex has passed, otherwise the pills will not have any effect.

It should be noted that postinor does not provide a complete guarantee of preventing pregnancy, and its effectiveness directly depends on the time of administration. So, a pill taken within the first 24 hours after sex gives the maximum guarantee - 95%, the effect of the drug on the second day is 80%, and on the third - about 50%.

Experts recommend using emergency contraception only in extreme cases and with a doctor's prescription. Also, you should not abuse it; it is better to think about protection in advance and use oral or barrier contraceptives. It is considered relatively safe to take postinor no more than two to three times a year.

Side effects

Among the side effects, the most common are uterine bleeding. This is due to an increase in the level of gestagen, which is responsible for the formation of the inner surface of the uterus. An overdose of the drug or non-compliance with the instructions can lead to severe bleeding, if which occurs, you should immediately consult a doctor.

The following may also appear: nausea, headache, vomiting, dizziness, pain in the lower abdomen, menstrual irregularities, allergic reactions.

It is believed that postinor, when used once, is not capable of causing any serious disorders in the body. However, we note that this statement is only true for completely healthy women. The majority are faced with various deviations in the functioning of certain systems and organs, not suspecting that all this is the result of the use of postinor.

Effect on the reproductive system. Menstrual irregularities associated with the use of this drug always occur, but are individual for each woman. For some, they manifest themselves in the form of minor intermenstrual bleeding, for others - in the form of 3-7 day delays, and for others - in the form of a long-term cycle failure, which can subsequently cause infertility.

Effect on blood vessels. The lethal doses of hormones contained in these tablets can affect blood clotting, which leads to the formation of blood clots. As a rule, changes in blood clotting occur either with repeated use of the drug, or in women who already have disorders of the vascular system or are prone to similar diseases. Such changes are dangerous, as they can lead to blockage of blood vessels and disruption of blood supply to certain organs, as well as to the risk of stroke.

Among contraceptive drugs, Postinor occupies a separate place. It helps not only before sexual intercourse, but also for 3 days after. The drug belongs to the group of progestogens and reduces the level of female sex hormones. Each tablet contains 750 mg of levonorgestrel, a synthetic hormone that prevents ovulation.

The drug is taken in a dosage of 2 tablets during the first three days after unprotected sexual intercourse. The break between taking tablets is 12-16 hours. The drug is suitable for use at any time of the cycle. If more than 1 unprotected sexual intercourse occurs within a month, then Postinor should not be taken again.

Side effects

The drug is extremely aggressive. Gynecologists do not advise using it unless absolutely necessary. The drug is not guaranteed to prevent pregnancy, but it reduces the likelihood of conception by 58-95%, depending on the time of use. In this case, side effects occur in 80% of cases. Not all of them manifest themselves immediately. Delayed consequences are considered dangerous. They deal a blow to the gynecological area and provoke irreversible consequences for women's health.

Primary

Allergic reactions to Postinor manifest themselves in the form of redness of the skin, itching, and extensive rash. Specific therapy for allergic dermatitis to the drug is not required. Taking antihistamines relieves unpleasant symptoms. If you are prone to allergies, you should consult your doctor before using the tablets. In rare cases, the drug causes suffocation and swelling.

During the first days after administration, side effects such as:

• nausea and vomiting - if a woman vomits immediately, it is recommended to take Postinor again;
• headache and dizziness;
• diarrhea;
• pain in the stomach and lower abdomen;
• acyclic discharge with blood;
• chest pain and swelling of the mammary glands;
• increase in body temperature.

If a woman has problems with the liver and kidneys, then taking birth control pills can be harmful to health and cause functional failure.

Bleeding

After taking Postinor, your period may start early. Doctors explain this by hormonal imbalances. If menstruation began at the wrong time, then this is not a reason to panic. Pay attention to the nature of the discharge and accompanying symptoms.

• Bloody discharge on the 7th day after emergency therapy is considered normal. If the drug is taken without taking into account contraindications, large blood losses with subsequent complications cannot be ruled out. Uterine bleeding can last up to 1 month.
• The length of time it takes for the body to recover after taking a powerful hormone varies. When bleeding does not stop for more than 5 days, chronic weakness appears, the skin turns pale, and the heartbeat quickens. Women's neglect of their own bodies provokes irreversible consequences for the reproductive sphere, including infertility. Bleeding involves heavy discharge over a long period of time.

If there is bleeding and the woman’s condition is cause for concern, an ambulance is called.. Blood loss indicates a possible pregnancy, which occurred either earlier or during the last cycle. The instructions indicate that taking the drug during pregnancy is prohibited. Women who use Postinor to induce spontaneous miscarriage may face serious complications.

Remote

Despite the fact that the drug acts instantly, the consequences of such treatment may take several days or even weeks to appear.

1. More often, women who use Postinor as their main method of contraception become victims of side effects. Due to hormonal surges, metabolic disorders occur. The result is weight gain.
2. At the same time, the skin deteriorates and the condition of the hair deteriorates. Secretory activity increases, the sebaceous glands produce more fat. Pimples and acne appear on the face, back and shoulders, every sexual intercourse is accompanied by discomfort, and thrush worsens.
3. The genitourinary system experiences the greatest damage. Chronic ailments recur, cystitis develops, and urination becomes painful. Women's cycles are disrupted and delays are observed. This complicates the selection of the optimal contraceptive method and increases the risk of unplanned pregnancy.
4. Problems with conception and embroidery are more common in those women who practiced contraception using Postinor. A one-time use of the drug does not lead to similar results, but addiction to pills disrupts the functions of the reproductive system and leads to consequences such as ectopic and frozen pregnancies, early miscarriages, and fetal pathologies.

No side effects

Women who have not experienced the negative consequences of Postinor are a minority. In their opinion, the drug appears to be universal and safe. But the absence of obvious complications does not indicate the safety of birth control pills for women's health.

The drug affects the endocrine system. As a result, the functioning of the thyroid gland will worsen, the woman will gain weight beyond measure, and blood viscosity and sugar levels will increase. In the future, this provokes atherosclerosis and problems with the musculoskeletal system. Pathological processes develop unnoticed, and the woman does not associate them with taking pills.

If Postinor did not cause side effects, then this is not a reason to recommend it to others. The drug is prohibited for thrombosis, age under 16 years, chronic diseases of the kidneys, biliary tract and liver, during pregnancy and lactation. In the latter case, the doctor may prescribe a drug to avoid re-pregnancy immediately after childbirth. Breastfeeding is suspended for a while, and the drug is taken once in double dosage. The final decision on the possibility of using Postinor is made by a gynecologist.

A synthetic drug with a contraceptive effect, pronounced gestagenic and antiestrogenic properties. With the recommended dosing regimen, levonorgestrel suppresses ovulation and fertilization if sexual intercourse occurs in the preovulatory phase, when the possibility of fertilization is greatest. It may also cause changes in the endometrium that prevent implantation. The drug is not effective if implantation has already occurred.

Efficacy: with the help of Postinor tablets, pregnancy can be prevented in approximately 85% of cases. The more time passes between sexual intercourse and taking the drug, the lower its effectiveness (95% during the first 24 hours, 85% from 24 to 48 hours and 58% from 48 to 72 hours). Thus, it is recommended to start taking Postinor tablets as soon as possible (but no later than 72 hours) after sexual intercourse, if no protective measures have been taken. At the recommended dose, levonorgestrel does not have a significant effect on blood clotting factors, fat and carbohydrate metabolism.

Pharmacokinetics

When Postinor is taken orally, the drug is quickly and almost completely absorbed. Absolute bioavailability is almost 100% of the dose taken. After taking 0.75 mg of levonorgestrel, Cmax in serum equal to 14.1 ng/ml is achieved after 1.6 hours. After reaching Cmax, the content of levonorgestrel decreases. T 1/2 is about 26 hours.

Levonorgestrel is excreted approximately equally by the kidneys and through the intestines exclusively in the form of metabolites. The biotransformation of levonorgestrel corresponds to the metabolism of steroids. Levonorgestrel is hydroxylated in the liver, metabolites are excreted in the form of conjugated glucuronides. Pharmacologically active metabolites of levonorgestrel are unknown. Levonorgestrel binds to serum albumin and sex hormone binding globulin (SHBG). Only 1.5% of the total dose is in free form, and 65% is associated with SHBG.

Release form

Tablets are white or almost white, disc-shaped, chamfered, with a circular engraving "INOR." on one side.

Excipients: colloidal silicon dioxide, potato starch, magnesium stearate, talc, corn starch, lactose monohydrate.

2 pcs. - blisters (1) - cardboard packs.

Dosage

The drug is taken orally. You must take 2 tablets in the first 72 hours after unprotected intercourse. The second tablet should be taken 12 hours (but not later than 16 hours) after taking the first tablet.

To achieve a more reliable effect, both tablets should be taken as soon as possible after unprotected intercourse (no later than 72 hours).

If vomiting occurs within 3 hours after the 1st or 2nd dose of the Postinor tablet, then another Postinor tablet should be taken.

Postinor can be used at any time of the menstrual cycle. In case of irregular menstrual cycle, pregnancy must first be excluded.

After taking emergency contraception, use a local barrier method (eg, condom, cervical cap) until your next period. The use of the drug during repeated unprotected sexual intercourse during one menstrual cycle is not recommended due to an increase in the frequency of acyclic spotting/bleeding.

Overdose

Increased severity of side effects. There is no specific antidote. Symptomatic therapy is carried out.

Interaction

When taking drugs that induce liver enzymes simultaneously, the metabolism of levonorgestrel is accelerated.

The following drugs may reduce the effectiveness of levonorgestrel: amprecavil, lansoprazole, nevirapine, oxcarbazepine, tacrolimus, topiramate, tretinoin, barbiturates including primidone, phenytoin and carbamazepine, drugs containing St. John's wort (Hypericum perforatum), and rifampicin, ritonavir, ampicillin, tetracycline, rifabutin, griseofulvin. Levonorgestrel reduces the effectiveness of hypoglycemic and anticoagulant (coumarin derivatives, phenindione) drugs. Increases plasma concentrations of GCS. Women taking these drugs should consult a doctor.

Drugs containing levonorgestrel may increase the risk of cyclosporine toxicity due to inhibition of its metabolism.

Side effects

Allergic reactions: possible - urticaria, rash, itching, swelling of the face.

Transient side effects that occur with varying frequency and do not require drug therapy: sometimes (1-10%) - vomiting, diarrhea, dizziness, headache, breast tenderness, delayed menstruation (no more than 5-7 days; if menstruation is delayed for more than long term, pregnancy must be excluded); often (more than 10%) - nausea, fatigue, pain in the lower abdomen, acyclic spotting (bleeding).

Indications

Emergency (postcoital) contraception (after unprotected sexual intercourse or unreliability of the contraceptive method used).

Contraindications

• adolescence up to 16 years;
• severe liver failure;
• pregnancy;
• rare hereditary diseases such as lactose intolerance, lactase deficiency or glucose-galactose malabsorption;
• hypersensitivity to the components of the drug.

With caution: diseases of the liver and biliary tract, jaundice (including a history), Crohn's disease, lactation.

Features of application

Use during pregnancy and breastfeeding

Postinor is contraindicated for use during pregnancy. If pregnancy occurs while using an emergency method of contraception, then based on the available data, no adverse effect of the drug on the fetus has been identified.

Levonorgestrel is excreted in breast milk. After taking the drug, breastfeeding should be stopped for 24 hours.

Use for liver dysfunction

The drug is prescribed with caution to patients with diseases of the liver and biliary tract; it is contraindicated in severe liver failure.

Use for renal impairment

Data on the use of the drug in patients with impaired renal function are not provided.

Use in children

The drug is contraindicated in adolescents under 16 years of age.

special instructions

Postinor should be used exclusively for emergency contraception. Repeated use of the drug Postinor during one menstrual cycle is not recommended.

The effectiveness of Postinor tablets after unprotected sexual intercourse, during which contraception was not used, decreases over time:

The drug does not replace the use of permanent methods of contraception. In most cases, Postinor does not affect the nature of the menstrual cycle. However, acyclic bleeding and a delay of menstruation for several days are possible. If menstruation is delayed by more than 5-7 days and its character changes (scanty or heavy discharge), pregnancy must be excluded. The appearance of pain in the lower abdomen and fainting may indicate an ectopic (ectopic) pregnancy.

Adolescents under 16 years of age, in exceptional cases (including rape), need to consult a gynecologist to confirm pregnancy.

After emergency contraception, a consultation with a gynecologist is recommended to select the most appropriate method of permanent contraception.

Emergency contraception does not protect against sexually transmitted diseases.

In case of gastrointestinal dysfunction (for example, Crohn's disease), the effectiveness of the drug may be reduced.

Impact on the ability to drive vehicles and operate machinery

The effect of Postinor on the ability to drive vehicles and operate machinery has not been studied.