In this article you can read the instructions for use of the drug Dimexide. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Dimexide in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Dimexide in the presence of existing structural analogues. Use for the treatment of arthrosis and arthritis, relieving inflammation and improving hair growth in adults, children, as well as during pregnancy and breastfeeding. Masks to improve hair growth and other forms of using the drug.

Dimexide- anti-inflammatory agent for external use. The mechanism of action is associated with the inactivation of hydroxyl radicals and improvement of metabolic processes in the inflammation site, reducing the speed of excitatory impulses in peripheral neurons. Has local anesthetic, local anti-inflammatory, analgesic and antimicrobial effects; has some fibrinolytic activity. Penetrates through the skin and other biological membranes, increasing their permeability to medicinal substances.

Indications

• rheumatoid arthritis;
• Bekhterev's disease;
• deforming osteoarthritis;
• scleroderma;
• erythema nodosum;
• bruises;
• sprains;
• traumatic infiltrates;
• inflammatory skin diseases;
• thrombophlebitis;
• acne;
• furunculosis (as part of complex therapy).

Release forms

Solution for external use.

Gel for external use 25%.

Concentrate for preparing a solution for external use.

Instructions for use and method of use

Externally, in the form of compresses, tampons, dressings (including occlusive). Typically 30-50% solutions are used:

• in the treatment of erysipelas and trophic ulcers - 50-100 ml of a 30-50% solution 2-3 times a day;
• for eczema, scleroderma - compresses with a 40-50% solution;
• for pustular skin diseases - 40% solution,
• for local anesthesia for pain syndromes - a compress with 100-150 ml of a 25-50% solution 2-3 times a day;
• when treating deep burns - bandages with a 20-30% solution.

Side effect

• allergic reactions;
• itchy dermatitis;
• contact dermatitis;
• erythema;
• dry skin;
• slight burning sensation;
• bronchospasm.

Contraindications

• impaired liver and/or kidney function;
• angina pectoris;
• myocardial infarction;
• severe atherosclerosis;
• glaucoma;
• cataract;
• coma;
• pregnancy;
• lactation.

Use during pregnancy and breastfeeding

Dimexide is contraindicated for use during pregnancy and lactation (breastfeeding).

special instructions

Dimexide is used with caution simultaneously with other drugs, as it may enhance their effect.

Before using dimethyl sulfoxide (the active ingredient of the drug Dimexide), it is recommended to test for drug tolerance.

Drug interactions

It is possible to use Dimexide in combination with heparin, antibiotics and NSAIDs in dosage forms for external use.

Increases absorption and enhances the effect of ethanol (alcohol), insulin.

Increases the sensitivity of microorganisms to aminoglycoside and beta-lactam antibiotics, chloramphenicol, rifampicin, griseofulvin.

Sensitizes the body to general anesthesia agents.

Analogues of the drug Dimexide

The drug Dimexide has no structural analogues for the active substance.

If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.

Dimexide has several properties that may make it one of the most important products in the treatment of cancer. It is a powerful free radical fighter and a master detoxifier. It can penetrate body tissues and individual cells, transporting other drugs with it.
Dimexide is anti-cancer on its own and becomes even more powerful when combined with other anti-cancer drugs. Any of these important properties of dimexide may be effective in treating cancer. Excellent results are obtained by treatment with dimexide in combination with laetrile Vitamin B-17 or amygdalin). Dimexide has been used in combination with laetrile to treat cancer since the 1970s. The combination of laetrile and dimexide, administered through a slow infusion, was first formally used by Elmer Thomassen, M.D., of Newport Beach, California, in 1977. The dropper contained: Dimexide - at the rate of 1 gram per 1 kg of body weight of the cancer patient, Laetrile - 6 grams, Vitamin "C" - 25 grams. Each infusion lasted 4 hours. IVs were placed five days a week for five weeks. After completing the course of treatment, the cancer patient took 60 grams of aloe vera juice with one teaspoon of dimexide, once a day.
Many doctors in the US, Mexico and other countries have reported success using laetrile and
dimexide in the treatment of patients with brain, liver, pancreas and other cancers that were considered fatal. These doctors say this treatment is usually more effective than chemotherapy or radiation.

Safety

Dimexide is one of the safest products ever used in medicine. It has been used by millions of people in the US and other countries, and there has not been a single case of death or serious injury. Now compare. The number of drug-related deaths in the United States is estimated at more than 200,000 per year, making drugs the third of the four leading causes of death. Even common painkillers called non-steroidal anti-inflammatory drugs (such as Advil, Mortin, Aleve and aspirin) account for about 7,600 deaths in the US each year. Taking this into account, it can be argued that dimexide is one of the safest substances in the world today. The classic toxicity test, the LD-50 test, measures the lethal dose at which half of a group of test animals will die. This test for aspirin and dimexide shows that aspirin is seven times more toxic than dimexide.

Side effects: When 60-90% dimexide is applied to the palm, the skin may remain wrinkled for several days. The garlic-like body odor and taste in the mouth are due to a specific metabolite (metabolic intermediate) of dimexide: dimethyl sulfide, a component of natural onion and garlic flavor. It can last from one to two days, and in a small percentage of people, especially men, the odor can be very strong. Drinking enough water will help dispel the odor. Other side effects of dimexide - such as stomach upset, headaches, nausea and sedation - are related to detoxification reactions. When dimexide is diluted with water, heat is generated. The bottle will be warm. This is a temporary, safe reaction.

Warning: Solutions of industrial dimexide contain admixtures of acid and acetone. Such dimexide cannot be used. Acetone can cause serious medical consequences. Long-term exposure to acetone can cause liver damage and death. Beware of this problem when you buy unreliable dimexide. Buy dimexide for medical purposes only from reliable suppliers.

A pure solution of dimexide becomes solid (like ice) in the refrigerator (not the freezer) within 2 hours. Harmful impurities do not have time to freeze during this time. If the bottle is turned over, small streams of poisonous water will flow through the ice. We only need ice in the bottle. To melt its crystals, carefully heat the bottle with the drug in a water bath (water temperature is about 60 ° C). When 50 percent remains unfrozen, the vial is removed and the remains are melted. The resulting dimethyl sulfoxide is almost odorless. The drug at a concentration of 26% inhibits the growth of all microorganisms in the blood of cancer patients. The use of DMSO in oncological practice is facilitated by its ability to conduct to the tumor and accumulate antitumor drugs in it.

Sulfur: The Substance of Life. When salt-rich ocean water evaporates, it is oxidized into dimexide. It then dissolves in atmospheric moisture, is captured by clouds and falls to the ground as rain or snow. Dimexide is found in all cells of the body. Sulfur is vital for numerous chemical reactions associated with the detoxification of drugs and other harmful toxins. Dimexide has about 40 pharmacological properties that can be useful in the treatment of many diseases. Garlic is a powerful healing agent mainly due to the sulfur it contains. Dimexide is effective for the same reason. In fact, this colorless, oily-looking liquid has a garlicky odor due to its sulfur content. The body uses sulfur to constantly create new cells and replace old ones. Without it, the body will produce weak and dysfunctional cells. Sulfur is also needed to maintain the permeability of cell membranes. For detoxification, it is important to ensure that nutrients enter the cell and toxins and waste products leave it. Sulfur is essential in the formation and maintenance of connective tissue, fighting inflammation, and maintaining a strong immune system. Sulfur deficiency is common due to the fact that sulfur is lost after food is processed. This results in slow wound healing, scar tissue, brittle nails and hair, digestive problems, inflammation, lung dysfunction, decreased immunity, arthritis, acne,
depression, memory loss.

Therapeutic properties. According to the medical and pharmaceutical literature, dimexide has perhaps the widest range of therapeutic actions ever demonstrated by a single chemical substance. Dimexide is useful for a wide variety of diseases and performs various functions. Dimexide has such
properties: analgesic, anti-inflammatory, bactericidal, antiviral, antifungal, vasodilator, fights free radicals, stimulates various types of immunity, diuretic. In addition, dimexide is able to transport various drugs through cell membranes, fights blood clots, acts as a tranquilizer (sedative) when rubbed into the skin, stimulates wound healing, creates interferon (proteins secreted by the body's cells in response to a virus invasion), increases efficiency antifungal and antibacterial agents and has a mass
other benefits.

Hydration: Dimexide is a solvent with an uncanny ability to penetrate the skin. Dr. Jacob explains that dimexide is the “alter ego” (translated from Latin as “another self”) of water. Its molecular bond with water is 1.3 times stronger than the molecular bond of water with water. As a result, it displaces water as it moves through cell membranes, and transports with it substances that normally cannot penetrate the cell on their own.

Painkiller: In his book Dimexide: Nature's Healer, Dr. Morton Walker states that people now have a new breakthrough in the fight against pain: Dimexide. Some researchers believe that dimexide "could become the aspirin of the 21st century." Despite the fact that all the mechanisms of the substance are not yet fully known, it is assumed that its action is that it blocks the C fibers of the peripheral nerves, which receive pain signals.

Free radicals: Dimexide is one of the most powerful free radical fighters known today, and perhaps the most powerful. Some molecules in our body produce an unequal number of electrons and this instability causes them to destroy other cells. Dimexide attaches to these molecules and then they are excreted from the body with dimexide. Dimexide replaces water in cells and thus treats diseased cells by destroying free radicals inside it. Thanks to these properties, dimexide is useful in the treatment of various diseases, including cancer, arthritis, and atherosclerosis.

Bioavailability: Dimexide applied to one area often results in decreased pain or various improvements in other areas due to its overall action. Thanks to its ability to penetrate, dimexide can carry healing properties deep through the tissues of the body. Another unusual property of dimexide, which greatly distinguishes it from other substances and drugs, is that it has a cumulative effect and does not require large doses.

Transporter & Dimexide acts as a transporter for other substances or drugs, and it can also enhance their effects. In fact, certain drugs diluted with dimexide, such as corticosteroids, antibiotics and insulin, can be used in lower doses than usual without reducing their therapeutic effectiveness and in addition their unwanted side effects are greatly reduced.

Immunity: Dimexide strengthens the immune system by increasing the production of white blood cells and macrophages, which destroy foreign substances and pathogens in the body. Dimexide activates macrophages, which makes them especially deadly against harmful microorganisms and cancer cells. Dimexide reduces allergic reactions by opening cell membranes and allows special antigens, substances that
stimulate the production of antibodies in the body. This process creates immunity to infectious diseases and the growth of malignant tumors.

Radioprotective properties: Dimexide is a classic sulfur compound. Sulfur has a long history of use as an antidote against acute injury from radioactive materials. A Japanese study showed that even small concentrations of dimexide have radioprotective effects. They help repair DNA double-strand breaks, and thus provide protection against radiation damage at all cellular levels of the body.

Frost-protective properties: Dimexide also has frost-protective properties. This means that it is able to protect against damage caused by frost. Before dimexide, there was no way to preserve organs without forming ice crystals that killed the tissue. In 1961, Dr. Jacob first became acquainted with the antifreeze properties of dimexide. Preserving organs for transplantation is still one of the many uses of dimexide. 100% dimexide will freeze at temperatures around 19°C, while a 50% solution of dimexide and water will not freeze at temperatures far below the normal freezing point
water.

Detoxification: Heavy metals (mercury, lead, aluminum, cadmium, arsenic, nickel) are very difficult to remove from the body and they cause many diseases. Dimexide may help detoxify from heavy metals. Sulfur is a mineral and the main ingredient of certain amino acids that binds to heavy metals (mercury, lead, aluminum, cadmium, arsenic, nickel) and removes them through urine, bowel movements and sweat. Dimexide (injected intravenously) helps eliminate amyloid proteins (Amyloidosis), which are the cause of Alzheimer's disease.

Methods of using the drug

Commercially available brands of DMSO vary widely in quality. Therefore, DMSO should only be used under the supervision of specialists who are familiar with
its properties and know how to use it. DMSO will carry whatever is on your skin into your bloodstream. Wash and rinse the area where you will apply it thoroughly. The same goes for your hands. Dimexide is usually applied to the skin in the form of a liquid, gel or cream. It can be taken by mouth or through an intravenous injection (in many cases, along with other medications). It is also prescribed subcutaneously, intramuscularly, intraperitoneally, intrathecally, through inhalation, to mucous membranes and into the bladder. Dimexide can also be instilled into the eyes. Concentrations and doses vary widely. People with white skin, blond or red hair and blue eyes are more sensitive to dimexide. For these, surface, oral or intravenous concentrations should be 50 percent or less, especially around the face and neck. Dimexide applied to the skin is completely absorbed after 4-8 hours. Dimexide taken orally reaches peak blood levels after 4 hours. In general, absorption through the skin is slightly less than through the digestive tract. Dimexide cannot quickly penetrate nails, hair or tooth enamel.

Surface application: The liquid form of dimexide is the most effective form of applying dimexide. It is advisable to begin superficial treatment with dimexide with low concentrations until the skin gets used to it over time. For any superficial use of dimexide, the skin must be clean, dry and undamaged. The face and neck are more sensitive to dimexide and therefore concentrations higher than 50% should not be applied to them. In areas where circulation is reduced, surface concentrations of dimexide should be below 70%. If 60%-90% dimexide is applied to the skin, warmth, redness, and tingling may occur. This usually goes away within a couple of hours. To prevent this effect, you can use natural aloe vera, gel or cream. In general, after superficial treatment with dimexide, it is recommended to apply aloe vera cream to the area, regardless of whether there is irritation on the skin or not.

Oral administration: The usual dose of dimexide for oral administration is 1-2 teaspoons (5-10 ml) per day. Dimexide is usually mixed with tomato or grape juice to mask its unpleasant taste. It is advisable to first start with half a teaspoon of dimexide and gradually increase (if any possible detoxification reactions are tolerated normally).

Intramuscular administration DMSO solutions do not cause interstitial damage, as evidenced by the absence of enzymeemia, which naturally occurs when cells and tissues are damaged. A therapeutic mixture of 3-5% DMSO solution with an antibiotic is infused intrabronchially. The drug is administered, if necessary, intraperitoneally, in the form of a 40-50% solution containing an antibiotic. The volume of injected solution can reach 1 liter. Calculations are based on a dose of 5 g of DMSO per 1 kg of patient body weight. A drug,
prepared in this way can also be used for plugging cavities. After administration of the drug, a feeling of warmth appears in the cavity. Treatment with this method is well tolerated. Both when applied topically and as an intravenous injection, it promotes wound healing, relieves pain, prevents cell damage, and improves symptoms of diseases. However, to pay for the healing effects of DMSO, those who use it must put up with an unusual side effect - a very unpleasant one.
the smell that their breath and body emit. This garlic-like odor is certainly one of the reasons why DMSO is not used.

Intravenous injections: Dimexide is not a drug for external use only. A 10-20% solution is administered intravenously at a rate of 0.5-0.8 and
even 1 g/kg weight. Intravenous administration should be carried out slowly, using an isotonic sodium chloride solution. The drug can be administered intravenously in combination with other drugs. The volume of intravenously administered (single) 10-20% dimexide solution can be 50-100 ml when treating patients with chronic inflammatory lung diseases. Up to 20 cubic cm of dimexide 25% concentration (dimexide must be diluted with sterile water), administered through intravenous
injection by a specially trained doctor to treat more serious degenerative diseases. Intravenous injection is done by slowly pushing the entire volume into the bloodstream at one time.

Intravenous drip (infusion): A slow intravenous drip is administered over 2-3 hour periods. 50-100 cc of dimexide added to 500 cc of glucose or saline solution is instilled into the patient’s arm vein. This method should only be performed by a qualified doctor.

Emergency medical assistance: Dimexide has certain properties that make it a very valuable agent in the treatment of victims of serious accidents or sudden serious illnesses such as heart attacks. Dimexide reduces swelling, is anti-inflammatory, increases oxygen supply, fights free radicals and helps protect cells from mechanical damage.

Inflammation. Inflammation is the body's complex response to injury or tissue destruction. In its acute form, it can be characterized by the classic signs: pain, swelling, heat, redness and loss of function. Dimexide works as a powerful anti-inflammatory agent. It can minimize all symptoms of inflammation. Patients' tumors shrank and localized heat cooled to normal. Patients also often noticed an immediate reduction in pain.

Additional recommendations: Numerous studies have revealed the amazing ability of dimethyl sulfoxide to easily penetrate the blood and human body through intact skin. 5-6 minutes after application to the skin, the presence of DMSO molecules is detected in the blood. The maximum concentration in the blood is created after 4-6 hours and decreases slowly over 36-72 hours. The effect of active medicinal substances is enhanced, since many of them directly enter the bloodstream, bypassing the digestive organs. Thanks to the powerful improvement in the permeability of drugs through the skin, their concentration contained in various ointments and rubs can be reduced several times! Thus, it has been proven that if about 20% DMSO is added to prednisolone ointment, then the concentration of prednisolone (without reducing the therapeutic effect) can be reduced by 8-10 times! This means not only significant savings on expensive drugs, but also a sharp reduction in the risk of unwanted side effects when treating patients. Dimexide has strong anti-inflammatory, antipyretic, antimicrobial, antifungal properties. As
30-50% solutions are used for diseases of the musculoskeletal system (rheumatoid arthritis, arthrosis, radiculitis, bruises and sprains, myositis,
traumatic infiltrates). And also for inflammatory skin diseases (furunculosis, erysipelas, purulent wounds, burns, thrombophlebitis).

Dimexide is one of the best remedies in the treatment of joint contracture - stiffness that develops as a result of the inflammatory process. Applied to the skin in the area of ​​inflamed joints and easily penetrating inside, DMSO relieves inflammation of the periarticular soft tissues and muscles. Dimexide accelerates wound healing and restores the activity of antibiotics in cases where microbes have already developed resistance to them, increases the body's resistance to low temperatures and radiation exposure.

The purified drug showed good results in secondary renal amyloidosis, a severe complication of rheumatoid arthritis accompanied by the deposition of insoluble protein in the kidneys. In this case, dimexide was administered orally, diluted 10-15 times with distilled water (1 tablespoon 2-3 times a day after meals). In the same form, the drug was used after irradiation of the pelvic organs and rectum (in connection with the treatment of malignant neoplasms). This allows you to relieve reactive tissue inflammation after radioactive exposure and protect healthy cells.

At home, you can prepare tinctures, balms and ointments based on dimexide to treat a wide variety of pathologies, even in severe, advanced cases.

To prepare tinctures, use frozen pharmaceutical dimexide, which, if necessary, is diluted with boiled water to a concentration of 30-70%. Based on 25-30% solutions of dimexide, you can prepare tinctures of chamomile, meadowsweet, salvia officinalis, St. John's wort, thyme and many other medicinal plants. All such tinctures are mainly used externally. If you are performing this procedure on someone other than yourself, you must wear rubber gloves to protect your own skin. Use during pregnancy and breastfeeding is contraindicated.

Externally (applications, irrigations). Apply gauze pads moistened with a diluted (1:1) solution to the affected areas once a day (for 20–30 minutes). For the skin of the face and other highly sensitive areas, more diluted solutions (1:10, 1:5, 1:3) are used (the same solutions can be used to wash purulent-necrotic and inflammatory lesions and cavities). A plastic film and cotton or linen cloth are placed on top of the napkin. Course - 10–15 days. Storage conditions for the drug Dimexide: in a dry place, protected from light. Keep out of the reach of children.

How to dilute Dimexide? Dimexide liquid concentrate must be diluted with water before use to obtain a solution of the required concentration. Undiluted concentrate causes chemical burns to the skin. Most often, Dimexide is diluted with water in a ratio of 1:3 or 1:4 (one part Dimexide, 3 or 4 parts water). But sometimes the doctor prescribes other dilutions of Dimexide for treatment. They are prepared as follows:

Solutions obtained by diluting the concentrate are used for compresses, applications, tampons and rinses (irrigations).

When used topically or as an intravenous injection, it promotes wound healing, relieves pain, prevents cell damage, and improves symptoms of a wide range of autoimmune diseases. DMSO can be used for so many different problems - from sprained ankles to arthritic pain and
previously considered incurable bladder dysfunction - that it is simply unbelievable. More than forty thousand studies have been devoted to DMSO, and many of them
have focused on its beneficial effects on human health.

Opponents of dimexide. First of all, these are the FDA (US Food and Drug Administration) and large pharmaceutical companies. Dimexide
sold in health food stores, online and most of the world. It has been used by millions, but in the US, dimexide is approved by the FDA only as a preservative.
stem cells, bone marrow cells and organs for transplantation, as well as for interstitial cystitis, a painful inflammatory disease of the urinary tract
bladder, which is very difficult to treat with other therapies. Dimexide is very cheap to produce. No drug company can obtain an exclusive patent because
It is also a natural compound, hence these companies will not be able to make significant financial profits. The president of a major pharmaceutical company said: “We don’t care that dimexide is the main drug of our century and we all know it, it’s just not worth anything to us.” Despite restrictions on the use of dimexide, thousands of Americans buy it on the black market every year , its popularity is not due to advertising, but thanks to the people who have benefited from dimexide. When you have something that cures all types of illnesses, including some incurable and life-threatening ones, people naturally recommend it to friends and family.

Dimexide is a synthetic drug for external use with antiseptic, analgesic, anti-inflammatory and fibrinolytic properties. The drug is used in the treatment of skin diseases, muscle and joint pain, and also in combination with other medications, enhancing their penetration through the skin and mucous membranes.

Dimexide (dimethyl sulfoxide) appears as a yellowish liquid with a faint garlic odor. The compound has the ability to easily penetrate into the blood through intact skin and perfectly dissolve chemical substances that differ in their structure: salts, alkaloids, antibiotics, vitamins, hormones, cytostatics.

Thanks to this, the drug accelerates the penetration of many substances through the skin without changing their properties (heparin, glucose, iodine, penicillins, hydrocortisone, diclofenac and organic complexes of medicinal plants.

Indications

Dimexide is used separately or as one of the components in the complex treatment of the following diseases:

• Pathologies of OPS - radiculitis, ankylosing spondylitis, rheumatoid arthritis, reactive synovitis, deforming osteoarthritis (with damage to periarticular tissues).
• Lupus erythematosus (discoid).
• Limited scleroderma.
• Reactive synovitis.
• Mycosis of the feet.
• Purulent wounds, trophic ulcers, furunculosis, acne.
• Traumatic infiltrates.
• Keloid scars.
• Thrombophlebitis.
• Sprained ligaments.
• Alopecia.

Directions for use and doses

The drug is made in the form of a concentrate, which is used in diluted form with the required percentage of the active substance. The solution is used to rinse (irrigate) or moisten compresses (tampons) for application to the affected areas, including adjacent healthy skin. The compress is covered with film and natural fabric. The duration of applications is from 10 to 15 days. Depending on the disease, Dimexide solution is used as follows:

• When treating trophic ulcers or erysipelas, 30-50% solution, 50-100 ml. 2-3 r. per day
• When treating diffuse streptoderma and eczema, compresses with 40-90% solution are applied.
• For pain and local anesthesia, 25-50% solution in the form of a compress of 100-150 ml. 2-3 r. In a day.
• On highly sensitive areas and facial skin, 10-30% solution is used.
• During plastic surgeries, bandages with a 10-20% solution are used, applied to the transplanted grafts immediately after surgery and during the postoperative period until they are completely healed. Skin grafts are stored in a preservative 5% solution of Dimexide and Ringer.
• Purulent-necrotic inflammatory foci and cavities are washed with solutions with a 10% concentration of the active substance.

To dilute Dimexide, the required amount of concentrate is poured into the container and distilled water is added. Instead of water, you can use vegetable oils, especially when using tampons. Various concentrations of the drug are obtained by mixing water and medication in the following proportions:

Contraindications

Dimexide is contraindicated in the following cases:

• In case of hypersensitivity to the drug.
• In severe renal or liver failure.
• Severe atherosclerosis.
• Myocardial infarction or angina pectoris.
• Cataracts or glaucoma.
• Stroke.
• Coma.
• During pregnancy and breastfeeding.
• Under 12 years of age.

Pregnancy and lactation

During pregnancy and breastfeeding Dimexide contraindicated.

Overdose

In case of an overdose of the drug, allergic reactions may occur. When using undiluted Dimexide, chemical burns may occur. Rubbing the drug and massaging it also causes burns.

Side effects

After using an aqueous solution of Dimexide, the following side effects are observed in rare cases:

• Allergic reaction.
• Pruritic and contact dermatitis.
• Burning and dry skin.
• Erythematous rash.
• Very rarely - bronchospasm.

If an allergic reaction occurs, stop using the drug and, if necessary, prescribe histamine H1 receptor blockers.

Composition and pharmacokinetics

Dimexide is available in the form of an orange glass dropper bottle with 25 ml. undiluted sulfoxide - a clear, colorless liquid with a slight odor, soluble in water and alcohol. Used to prepare a solution for external use. It has antiseptic, antipyretic, antihistamine, anti-inflammatory, analgesic and fibrinolytic effects.

Quickly penetrates biological membranes, including mucous membranes and skin, increasing their permeability to other drugs. When applied, it penetrates into the blood within 5 minutes, reaching a peak concentration after 5-6 hours. Changes the sensitivity of microflora that are resistant to antibiotics. It is used in combination with other drugs (pre-dissolved in it or after application to the skin) for high-quality and deep penetration into tissues.

Other

Before using the drug, a tolerance test must be carried out by applying the solution to the hand using a tampon. Hypersensitivity will be indicated by hyperemia and severe itching.

Dispensed by prescription. Shelf life 2 years. Store in a dry place, protected from light, out of reach of children.

Reviews

(Leave your feedback in the comments)

I tested the effect of the drug after consulting a mammologist, who prescribed Dimexide along with hormonal medications for the treatment of mastopathy. The doctor explained that if there is no effect, the nodules will have to be removed through surgery. The solution was applied for 10 days, half an hour each. The following diagnostics showed that the seals had begun to dissolve. In my case, the disease is treatable, I hope that everything will go away without the help of a surgeon.

On the steps I severely twisted my leg, after a short time the joint was swollen, and it was impossible to walk. At home, my mother-in-law (a nurse by profession) bought Dimexide and an elastic bandage, after which she prepared a solution, applied a compress for half an hour and wrapped her leg with a bandage. Until the next day the joint hurt. After the procedure, on the second day the pain decreased noticeably, by the third day the swelling began to subside, and they decided not to do the fourth compress. I think that without the medicine, recovery would have been noticeably longer.

* — Average value among several sellers at the time of monitoring, is not a public offer

Dimexide is a drug for topical use. It is used to treat various diseases of the joints, skin, ligaments and bones. It has antimicrobial, antiseptic and analgesic effects. Dimexide poisoning can develop due to improper or prolonged use. In this article, we looked at the symptoms that manifest this condition, first aid and treatment.

Description of the drug

Dimexide is available in the form of an aqueous solution, sold in bottles of 50 or 100 ml. This drug is sold without a medical prescription.

This the medicinal product is intended for topical use only. Drinking and swallowing it is strictly prohibited.

When applied to the skin, the medicine acts not only locally, but also, when absorbed, enters the bloodstream. Before starting treatment with this drug, you should consult your doctor.

Effect of the drug

Dimexide has a complex effect on the pathological focus. When applied to a problem area of ​​the body, it has the following effects:

• relieves pain. This drug used as a local anesthetic;
• reduces the severity of the inflammatory reaction;
• destroys pathogenic microorganisms that cause the inflammatory reaction;
• makes resistant bacteria sensitive to antibacterial therapy.

Dimexide is quickly absorbed and can act not only on the surface of the skin, but also in joints, bones, tendons and ligaments. Compresses with antibiotics, steroids and anti-inflammatory drugs are often made based on this medicine.

Doctors call dimexide a “conductor.” If it is necessary to facilitate the penetration of a drug into the subcutaneous layers, it is used together with dimexide.

Indications

Dimexide is widely used in modern medicine for the treatment of the following diseases:

• rheumatoid arthritis;
• Bekhterev's disease;
• sprain of the ligaments of the joints;
• arthrosis and arthritis of various etiologies;
• traumatic infiltrates;
• bruises;
• abscesses and phlegmons;
• purulent wounds;
• boils and carbuncles;
• osteomyelitis;
• trophic ulcers.

Contraindications

Dimexide, absorbed into the blood, affects the entire body. It should absolutely not be used for:

• acute or chronic renal failure;
• allergic intolerance to the drug or its components;
• coronary heart disease in the form of angina pectoris, myocardial ischemia;
• increased intraocular pressure, glaucoma, cataracts;
• impaired consciousness of the patient, comatose state;
• pregnancy and lactation;
• children under 12 years of age.

Drug poisoning

Dimexide poisoning can develop as a result of its improper use or long-term treatment with it. Also at risk are people who decide to self-medicate.

With topical use of dimexide, overdose occurs extremely rarely. She may occur if a person ingests the drug orally.

A child can be poisoned by medicine by accidentally drinking a bottle. Children love to taste everything, so all medications without exception should be stored in places inaccessible to them.

In case of an overdose of the drug, an acute allergic reaction may develop. Most often it occurs in the form of urticaria. The patient develops red, streakless rashes. This rash is characterized by severe itching.

In rare cases, a more pronounced allergic reaction develops - in the form of angioedema. At the same time, the patient’s face begins to swell, especially the eyelids and lips. Swelling can also develop in the oropharynx, leading to asphyxia and suffocation. The patient begins to cough and feel short of air.

What to do if you develop an allergy to a drug

If an acute allergic reaction develops you need to call an ambulance immediately. Describe the patient’s condition to the dispatcher and give the correct address. While waiting for doctors, you need to begin to provide first aid to the victim yourself. Below are its main components:

1. Thoroughly rinse any remaining product from the skin.
2. Open the windows in the room in which the patient is located, and make sure that no items of clothing interfere with his breathing.
3. If you have antihistamines (anti-allergic) drugs in your home medicine cabinet, give them to the patient to drink. In this case, you must strictly follow the dosage rules specified in the instructions.
4. If poisoning has developed as a result of taking the drug orally, you need to give the poisoned person to drink several glasses of water and then induce vomiting. Then the patient needs to take a sorbent, for example, activated carbon, or enterosgel.

The ambulance team, upon arriving at the call, will examine the patient and determine the severity of his condition. For angioedema, the following drugs are administered intravenously:

• antihistamines, for example, diphenhydramine or suprastin.
• corticosteroids - dexamethasone or prednisolone.

If the patient’s condition does not improve after the medications are administered, he is taken to the nearest on-duty hospital to the therapy department.

Side effects of dimexide

The drug dimexide may cause side effects. They may occur even if the drug is used correctly. Side effects of dimexide include the following conditions:

• dizziness;
• itching and redness of the skin;
• sleep disturbance, insomnia;
• diarrhea;
• general lethargy, fatigue, weakness;
• bronchospasm;
• nausea and vomiting;
• abdominal pain.

If the above symptoms appear, you should immediately stop using the drug. Then you need to wash it off the skin and contact your doctor.

Most of these symptoms disappear after stopping the drug. Your doctor will prescribe you a different medicine.

Dimexide is widely used to treat inflammatory diseases of the joints and skin. Before you start using it, you should definitely consult your doctor.. In case of an overdose of this medicine, allergies may develop in the form of urticaria or angioedema. If an acute allergic reaction develops, you should call an ambulance and take an antihistamine.

Dimexide (ointment, gel suppositories) – instructions for use, prices and reviews

Thank you

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

Definition

Dimexide– a local anti-inflammatory drug used for joint and muscle pain and many other diseases. It is a clear, colorless liquid, but with a characteristic odor reminiscent of garlic. Easily dissolves in water and alcohol. At temperatures below 16 o C it crystallizes.

Instructions for use

Compound

Dimexide is 99% or 100% composed of a substance called dimethyl sulfoxide. The properties of 100% and 99% drugs are practically no different.

Release forms

Dimexide is available in several forms:
1. Liquid concentrate in dark glass bottles of 40, 50, 60, 80, 100 and 120 ml. From the concentrate, by diluting it, solutions are prepared for direct use.
Dimexide ZhFF (Zhytomyr Pharmaceutical Factory) and Dimexide Lugal (Lugansk Chemical Plant) are no different from just Dimexide.
2. Dimexide gel 25% and 50% in aluminum 40-gram tubes.
3. Propolis-D suppositories: they contain both propolis and dimexide. These substances, when used together, mutually enhance each other's medicinal properties. Suppositories are used both intravaginally (in the vagina, for gynecological diseases) and rectally (for the treatment of hemorrhoids). Suppositories containing only Dimexide are not available.
4. Dimexide ointment contains from 30% to 70% dimexide itself. In addition, the ointment contains polyethylene oxide gel 1500 and an emulsifier (auxiliary substance). There is also Dimexide ointment based on mink oil.

Dimexide is not available in ampoules.

Properties and effect on the body

Dimexide is a local anesthetic and anti-inflammatory agent. It has a detrimental effect on bacteria. But the most valuable property of dimexide for medicine is its ability to easily and quickly penetrate deep into tissues, through the skin and mucous membranes. At the same time, it carries with it those substances that are dissolved in it and “transports” them to the site of inflammation.

Therefore, Dimexide is most often used in combination with other medications previously dissolved in it (antibiotics, hormones, heparin, etc.).

Only topical use of Dimexide is allowed, because if ingested, it becomes a toxin or poison for humans. Even a few drops of this substance taken orally cause nausea, vomiting and intestinal dysfunction. Dimexide also enhances the toxic properties of other drugs.

Topical use of this drug should also be carried out with caution: the undiluted concentrate, coming into contact with the skin and mucous membranes, causes them to burn.

The properties of Dimexide do not change after freezing and subsequent thawing.

Indications for use

• diseases and injuries of the musculoskeletal system (bruises, sprains, arthritis and arthrosis, radiculitis, etc.);
• pustular and inflammatory skin diseases (acne, furunculosis, eczema, erysipelas, etc.);
• poorly healing infected (purulent) wounds;
• burns;
• haemorrhoids;
• trophic ulcers of soft tissues;
• inflammatory dental diseases (pulpitis, periodontitis);
• preservation of skin grafts (used in plastic surgery).

Contraindications

• cardiovascular diseases (angina pectoris, atherosclerosis);
• insufficiency of liver and kidney function;
• pregnancy and breastfeeding;
• age under 12 years and old age;
• individual intolerance to the drug.

Side effects

• local allergic reactions (dry skin, burning and itching, rash);
• general lethargy, slow reactions;
• diarrhea (diarrhea);
• nausea, vomiting;
• bronchospasm (in case of individual intolerance to Dimexide).

Application and dosage

How to dilute Dimexide?
Dimexide liquid concentrate must be diluted with water before use to obtain a solution of the required concentration. Undiluted concentrate causes chemical burns to the skin. Most often, Dimexide is diluted with water in a ratio of 1:3 or 1:4 (one part Dimexide, 3 or 4 parts water).

But sometimes the doctor prescribes other dilutions of Dimexide for treatment. They are prepared as follows:

Solutions obtained by diluting the concentrate are used for compresses, applications, tampons and rinses (irrigations).

How to make a compress with Dimexide?
To make a compress, moisten 4-5 layers of gauze napkins with the resulting solution, and apply these napkins to the sore spot for 20-30 minutes. The napkin is cut to such a size that the edges of the compress extend onto healthy skin. A piece of plastic film and a linen or cotton cloth folded several times are placed on top of the napkin.

Application is the same as a compress, but is applied for a shorter time: 10-15 minutes. The duration of treatment with compresses and Dimexide applications is 10-15 days.

Before applying the compress, you can lubricate the skin over the sore spot with some anti-inflammatory ointment (Voltaren Emulgel, Dolgit cream, Fastum gel, etc.): Dimexide will improve their penetration through the skin.

• when treating bruises, it is recommended to apply compresses with a 25-50% Dimexide solution;
• for burns - with a 20-30% solution;
• for boils, acne - with a 40% solution;
• for erysipelas and trophic ulcers - with a 30-50% solution;
• for eczema - with 40% - 90% solution;
• When applying compresses and applications to the skin of the face and mucous membranes, a 10-20% solution of Dimexide is used.

Applications with Dimexide gel
Applications with Dimexide gel are carried out as follows: a small amount of 50% Dimexide gel is applied to the affected area of ​​skin in a thin layer and rubbed in gently.

A 25% gel is applied to the mucous membranes, facial skin and other sensitive areas of the body.

You can carry out 2-3 applications per day.

Ethyl alcohol (alcohol) slows down the removal of Dimexide from the body. Dimexide enhances the effect of alcohol. Therefore, it is not recommended to drink alcohol during treatment with Dimexide.

Additional instructions

Before starting treatment with Dimexide, it is recommended to test the patient's tolerance to this drug. To do this, a 25-30% aqueous solution of Dimexide is applied to a small area of ​​the patient’s skin with a swab. If after a few minutes the skin turns red and itches, it means that this person is hypersensitive to Dimexide, and treatment with this drug is contraindicated for him.

Considering the possibility of side effects of Dimexide such as slow reactions and dizziness, patients are advised to avoid driving during treatment with this drug.

Use during pregnancy and lactation

Pregnancy and lactation are contraindications for the use of Dimexide.

Propolis-D suppositories are used as an adjuvant; they enhance the effectiveness of the main treatment. They are used by inserting 1 suppository into the vagina 2 times a day. Treatment lasts from 10 to 14 days. If necessary, the course can be repeated (as prescribed by the gynecologist).

Dimexide for the treatment of joints

Compresses and applications with Dimexide are effective for joint diseases such as arthritis and arthrosis. Compresses with a 50% aqueous solution of Dimexide are applied to the affected joints. The application time of the compress is 30 minutes – 1 hour. 1 procedure is performed per day. The duration of treatment is from 15 to 20 days.

For severe joint pain, novocaine or lidocaine is added to Dimexide for compresses. For example:

• 30 ml of Dimexide concentrate;
• 50 ml of 2% novocaine;
• 50 ml of aqueous solution of furatsilin;
• 50 ml of 70-degree alcohol.

Another option:

• 10 ml of Dimexide concentrate;
• 10 ml of 2% lidocaine;
• 30 ml water.

You can also use compresses with 50% Dimexide gel.

Application of Dimexide in cosmetology

In cosmetology, Dimexide is used due to its bactericidal (antimicrobial) and anti-inflammatory properties. Compresses and masks with Dimexide have a beneficial effect on irritated, inflamed, acne-prone skin.

Face masks

A mask with tea tree oil and Dimexide is popular in cosmetology for the treatment of purulent-inflammatory diseases. Tea tree oil also has strong anti-inflammatory properties, and when mixed with Dimexide, these properties are enhanced.

A 10% aqueous solution of Dimexide should be mixed with tea tree oil, taking both substances in equal quantities. This mask is applied to the face not completely, but pointwise, only on inflamed areas of the skin (using a cotton swab). You can leave the mask on your face for several hours, or even overnight, then wipe your face with clean water using a swab. If a burning sensation occurs, immediately wash off the mask with water.

Treatment of acne (acne)

Masks with Dimexide are very effective in the fight against acne (or pimples - they are the same thing). You can simply wipe the affected areas with a 10% aqueous solution of Dimexide 2 times a day. You can make more complex mixtures for this purpose:

1. Dissolve 2 Erythromycin tablets in a 10% solution of Dimexide. Wipe your face (after the tablets have completely dissolved) 2 times a day.

2. Mix:

• 4 table. spoons of Dimexide concentrate;
• 50 ml of 2% salicylic alcohol;
• contents of 10 ampoules of 1% solution of Dioxidin;
• 40 ml glycerin.

Wipe “problem” areas with this mixture 2 times a day.

Hair masks with Dimexide

Dimexide, when used in combination with vitamins and various oils, improves hair structure and promotes hair growth. An important condition for the successful use of hair masks is thorough mixing of all components, and after this the immediate application of the mask to the hair.

Mask for hair growth and strengthening
The following components are required: Dimexide, castor oil, burdock oil, one ampoule of vitamins A and E, lemon essential oil (or lemon juice).

First, mix a tablespoon of castor oil with the same amount of burdock oil. Then add the contents of ampoules with vitamins and 4-5 drops of lemon juice or lemon essential oil to the mixture of oils. Lastly, add a tablespoon of Dimexide concentrate.

After thoroughly mixing everything, rub the resulting mixture into the hair roots, put on a plastic cap, and wrap your head with a towel on top for warmth. An hour later, you need to wash your hair with shampoo.

If a burning sensation appears in the scalp, the mask should be washed off immediately.

Mask with sea buckthorn oil for fast hair growth
For this mask, mix equal parts sea buckthorn oil with a 50% aqueous solution of Dimexide. Mix thoroughly and apply in the same way as described in the previous recipe. At the end of the procedure, it is recommended to rinse washed hair with apple cider vinegar diluted with water 1:10.

Mask for oily hair
The mixture for this mask is prepared from the following components, taken in equal quantities (a teaspoon):

• Dimexide concentrate;
• ampoule solution of vitamin E;
• ampoule solution of vitamin A;
• lemon juice (or 70-proof alcohol, vodka, cognac).

Use the same as in previous recipes. This mask should be left on your hair for half an hour.