List of effective immunomodulators. List of inexpensive but effective antiviral drugs for influenza and ARVI. Pros and cons of other antiviral drugs

Immunomodulators for colds are now taken so often that the question arises whether these drugs are not prescribed to us too often. On the one hand, it is obvious that to suppress such seasonal diseases as colds, sore throat, flu or ARVI, the immune system of the majority of people is not strong enough, moreover, it is weakened by the disease and requires additional support. On the other hand, now not every doctor, not to mention ordinary consumers, is well versed in the issue of proper prescription and use of immunomodulators for colds. After all, modern immunomodulators for ARVI are presented on the market in such abundance that even a specialist can easily get confused. In addition, when promoting their immunomodulators on the market, pharmaceutical companies often disseminate inaccurate or deliberately false information about competitors' products. Immunomodulators for colds, how effective are they, how do they work and are they safe for our health and the health of our children?

How modern immunomodulators work

Immunomodulators antiviral list

Many modern immunomodulators- these are drugs of narrow “specialization”. That is, they stimulate one of the components of the immune system. That is why and the help of a qualified doctor is necessary, because it is extremely difficult, one might even say impossible, to determine on your own where exactly the “breakdown” occurred. To ensure that strong immunomodulators do not harm the immune system, you first need to conduct a special analysis - an immunogram, which will show how well the immune system works or how weakened the immune system is. And based on its results, you need to select immunomodulators. Unfortunately, the cost of an immunogram may not be cheap, so it is often not performed and immunomodulators are prescribed at random for colds.
If you do not know which part of your immune system has failed, prefer immunomodulators for colds that have a wide spectrum of protective effects, for example Viferon, Gripferon. They contain interferon, a special protein that makes cells immune to the virus. Many modern immunomodulators have an antiviral effect. Antiviral immunomodulators list:
- Altevir (injection solution);
- Amiksin (tablets);
- Anaferon (lozenges);
- Arbidol (tablets);
- Viferon (rectal suppositories);
- Genferon (rectal suppositories);
- Grippferon (nasal drops);
- Isoprinosine (tablets);
- Ingaron (injection solution);
- Infagel (ointment);
- Lavomax (tablets).
- Neovir (solution for injection);
- Reaferon EC (powder for solution; administered intravenously);
- Ridostin (injection solution);
- Transfer Factor advance;
- Epigen Intim (spray);

Transfer Factor for colds

All of the above antiviral immunomodulators may have undesirable consequences. The only exception to the list is the drug Transfer Factor, a natural immunomodulator obtained from cow colostrum and chicken egg yolks. The drug Transfer Factor is a natural endogenous immunomodulator, the basis which consists of substances - molecules transfer factors that take part in the regulation of immune processes in the human and animal body. Transfer Factor causes stimulation of the cellular and humoral components of the immune system, in particular killer lymphocytes, which activate the production of immunocytokines. The drug Transfer Factor is a universal immunocorrector, and therefore can be recommended for a fairly wide range of infectious and non-infectious diseases. Transfer Factor for colds, flu, ARVI and sore throat - this is the most effective immunomodulator. Transfer Factor is used for colds and for preventive purposes, especially before the onset of epidemics, in the autumn-winter period, when the body is especially weakened. Colds in children are also a reason to start taking Transfer Factor. It is absolutely safe for the child’s body, so there is no harm, but the benefits are enormous. Transfer Factor will help strengthen the child’s immunity and live through the autumn-winter period without colds. You can see this for yourself by ordering Transfer Factor on our website.

Viruses are microscopic organisms; when they enter a person, they invade the cells of organs, multiply in them and feed on the cellular contents; as a result of such actions, the cell dies. Viral diseases are divided into zoonotic (transmitted from animals to people) and anthroponotic (spread from people to people).

Antiviral drugs are designed to treat diseases caused by viruses: influenza and ARVI. These medications have a certain effect on viral pathogens, which helps stop their reproduction.

Today you can buy various antiviral drugs at the pharmacy, including effective and inexpensive ones. They can be used directly to treat an existing disease, or for prevention.

Operating principle

With the help of antiviral drugs, the causes of the occurrence and development of ARVI are eliminated.

The results of this action are:

1. Reducing the risks of exacerbations of chronic diseases (, etc.).
2. Reducing the duration of a cold by several days, alleviating its symptoms.
3. Reducing the risk that severe complications will appear after suffering an acute respiratory illness.

In the case of a cold, they are also used as emergency prevention when one of the family members is sick and the risk of infecting others needs to be reduced.

What are they?

Based on the principle of action, these drugs are divided into two groups:

• stimulating the immune system to attack viruses;
• directly attacking viruses.

Also, antiviral agents, widely used for colds and viral diseases in 2019, can be conditionally divide into several large groups:

1. A group of nucleosides, which includes Acyclovir, Ganciclovir, Vidarabine, Zidovudine, Idoxuridine, Trifluridine, Ribamidili, etc.;
2. Interferon and interferon inducers: Interlock, Reaferon, Laferon, Intron A, Betaferon, Neovir, Poludan;
3. Adamantane derivatives: Remantadine, Midantan, Arbidol, Oxolin, Riodoxol, Florenal, Bonafton, Adapromin, Metisazone;
4. Lipid derivatives, the main representative is Saquinavir;
5. Ladolcarbolic acid derivatives: Foscarnet;
6. Thiosemicarbazone derivatives: Metisazone;
7. Plant origin: Flacoside, Alpidarin, Cholepin, Ligosin, Gossypol.

In addition, there are two large groups based on the principle of action:

1. Immunostimulants – drugs that enhance nonspecific immunity for a short period of time promote the production of interferon.
2. Vaccines are special serums that stimulate the secretion of antibodies even before the onset of the disease.
3. - agents that affect neuraminidase (viral enzyme), suppressing the reproduction of the virus.

Popular drugs

The best drugs used for ARVI and influenza:

1. (280 rubles);
2. (220 rubles);
3. (250 rubles);
4. (100 rubles);
5. (300 rubles);
6. Tiloron ( , ) – 650 rubles;
7. (applicable only for influenza, price 1,250 rubles.).

Let's take a closer look at which of these drugs in 2019 copes most effectively with viruses, but at the same time is inexpensive.

An antiviral agent that has the ability to suppress influenza A and B viruses, SARS - severe acute respiratory syndrome associated coronavirus. Arbidol is also used in the complex therapy of acute rotavirus intestinal infections. Active ingredient: methylphenylthiomethyl-dimethylaminomethyl-hydroxybromindole carboxylic acid ethyl ester.

Among the side effects from taking the drug, allergic reactions in the form of skin rash are known, its main contraindication is early childhood, intolerance to the components.

As a result of the action of the drug, the following is observed:

• antiviral and immunostimulating effect;
• reduction of toxic symptoms and clinical manifestations during the development of the disease;
• reducing the incidence of complications such as the development of bronchitis or pneumonia due to viral infection;
• increasing the period of remission with frequent exacerbations of chronic bacterial infections.

The daily dose of Arbidol for an adult in the treatment of ARVI is 200 mg, for a child from 6 to 12 years old - 100 mg, for a child from 3 to 6 years old - 50 mg. The drug should be taken before meals with plenty of water. Price: Arbidol - on average 130-710 rubles.

It is an immunomodulatory and antiviral agent. Cycloferon is used to treat ARVI, influenza and herpes viruses. Available in solution for injection, tablets, liniment.

It starts a certain cycle of interferon production in the body and maintains it at the proper level, despite rapid excretion by the kidneys. The drug interacts well with antiviral agents, chemotherapy drugs, and other stimulators of interferon production.

For ARVI, the daily dose of Cycloferon is 6 tablets. The course of treatment lasts no more than 10 days. The drug is taken half an hour before meals, 3-4 times a day. Experts recommend taking Cycloferon as a prophylaxis against acute respiratory infections in the autumn-winter period.

The active ingredient is the sodium salt of the copolymer gossypol with carboxymethylcellulose. Pharmacological action: inducer of interferon synthesis, has an antiviral, immunomodulatory effect.

The greatest effect occurs if treatment is started within the first 24 hours of the disease, but no later than the 4th day after the onset of acute infection. For prevention purposes, it can be taken at any time, preferably immediately after contact with a patient with acute respiratory viral infection or influenza.

Kagocel contains the polyphenol Gossypol, which is very active against influenza viruses. When taking a single dose, the maximum concentration of interferon in the blood is observed, which determines its rapid effect.

The effectiveness of therapy is quite high. However, Western clinics have come to the conclusion that treatment with Kagocel can lead to undesirable consequences due to the toxicity of Gossypol. Domestic researchers have not come to a clear conclusion, so the practice of treatment with Kagocel is not uncommon. The drug is inexpensive, the price of Kagocel is on average 180-280 rubles.

Pharmacological action: an antiviral drug, an adamantane derivative, suppresses various strains of the influenza A virus. The mechanism of action of rimantadine is to inhibit the reproduction of the virus by disrupting the formation of its envelope.

For medicinal purposes, it is recommended to take according to the following regimen: 1st day – 100 mg (2 tablets) three times a day, 2nd, 3rd days – two tablets twice a day, 4th, 5th day – two tablets once a day. For prevention, one tablet (50 g) is prescribed once a day for 10-14 days.

Rimantadine is available in the form of tablets and syrup; it is contraindicated during pregnancy and breastfeeding, intolerance to the components of the drug, liver failure, and is not prescribed for the treatment of children under 1 year of age.

Side effects include: nausea and vomiting, dryness, unpleasant taste in the mouth, decreased appetite, fatigue, headache, dizziness. There may be signs of disruption of the central nervous system. Price: Remantadine - on average 50-150 rubles.

Complex immunostimulating, antiviral drug, has an interferonogenic effect. The medicine contains Thymogen sodium, ascorbic acid, bendazole.

Positioned as an interferon inducer with an effect similar to Kagocel and Tiloron. It is assumed that bendazole enhances the production of endogenous interferon. Available in the form of capsules, syrup and powder for dissolution. Indications: treatment of influenza and ARVI in the early stages.

There are quite a lot of reviews from patients using Cytovir about the effectiveness and absence of side effects. Improvement in well-being is observed on the second or third day; in isolated cases, the drug did not help. Price: Tsitovir 3 - on average 240-580 rubles.

Tiloron (Amiksin, Lavomax)

The active substance Tiloron has antiviral and immunomodulatory effects; it is a synthetic interferon inducer that stimulates the formation of interferons alpha, beta, and gamma.

For influenza and other acute respiratory viral infections, adults are recommended to take 125 mg orally once a day for the first two days of illness, and starting from the 3rd day - 125 mg once every 48 hours. The dose per course of treatment is 750 mg. For the purpose of prevention, 125 mg is prescribed orally once a week for 6 weeks. Price: Amiksin - on average 500-560 rubles.

An antiviral drug, which includes oseltamivir carboxylate (active metabolite), suppresses influenza A and B viruses. It is not effective for acute respiratory viral infections.

The drug is not a preventative measure due to its severe toxicity. Long-term treatment with Tamiflu can lead to mental disorders and impaired renal function. Available in capsule form and in powder form for suspension.

Side effects: nausea, insomnia, diarrhea, dizziness, lethargy, cough, headaches, use with caution in pregnant women and during lactation. Contraindicated for children under 1 year of age.

In addition to such adverse reactions, the drug has one more difference: the prohibitively high price of 1000-1400 rubles.

Conclusion

In general, taking antiviral drugs helps reduce the duration of acute respiratory viral infections by several days, reduces the possibility of getting complications from an infection or exacerbation of existing chronic pathologies.

In mild forms of the disease, you can do without taking antiviral drugs: the immune system itself will fight the infection. However, if a cough or runny nose appears suddenly and is severe, plus the temperature has risen, then it makes sense to use it.

Also remember that the maximum effectiveness of these drugs is manifested at the very beginning of the disease; on the 3-5th day of the course of ARVI, taking them does not make much sense.

Modern immunostimulating drugs are classified according to their origin into the following groups:

• Herbal remedies - extracts or tinctures of Echinacea, Eleutherococcus, Schisandra, Immunal, etc. These remedies have a mild adaptogenic and immunostimulating effect and are prescribed to patients with immunodeficiencies. When taken prophylactically, such drugs significantly reduce the risk of influenza or respiratory infections, prevent radiation pathology and reduce harm from cytostatics;
• Microbial preparations - Imudon, IRS-19, etc. The drugs act directly on macrophages and monocytes, which, after activation, intensively produce cytokines that trigger immune reactions that promote the elimination of microbes;
• Interferon agents – Anaferon, Viferon. The drugs protect the body from various types of antigenic attacks of bacterial, viral and other origins;
• Synthetic drugs - Amiksin, Trekrezan, etc. Increase overall organic resistance to negative external influences and stimulate immune reactions;
• Endogenous agents – Thymogen, Timalin. These are drugs based on placental or bone marrow cells or thymus. They restore the normal number of blood cells, cause increased interferon production and immune activity.

It is strictly not recommended to take drugs with adaptogenic or immunomodulatory activity on your own; the need for their use should be determined by an immunologist.

Popular drugs

Trekrezan (250 RUR*)

The adaptogenic immunomodulator Trecrezan stimulates interferon production, corrects and improves the patient's immune status. As a result of using the medication:

• Increases the body's endurance during mental and physical stress;
• The toxic effects of various medications and chemicals are reduced;
• The body becomes especially resistant to oxygen deficiency, temperature changes and other aggressive factors.

Thanks to such effects, Trekrezan is successfully used for therapeutic and prophylactic purposes for respiratory infections, flu or colds. In the presence of stressful influences (for example, lack of oxygen, hypothermia or overheating), it helps to increase the performance and resistance of the body.

This immunomodulator is prescribed for the complex treatment of alcohol withdrawal or heavy metal poisoning. The drug is contraindicated during pregnancy, children under 12 years of age and pregnant women with lactose intolerance.

Immunal, Echinacea (300 RUR*)

Immunal contains components of plant origin (echinacea juice). The drug provokes an increase in nonspecific immunity. By activating phagocytosis and increasing leukocytes, the drug inhibits the reproduction and growth of pathogenic microorganisms. In addition, Immunal has antiviral activity against herpes or influenza. The preparations Echinacea and Immunal are analogues, having the same active ingredient (extract from the Echinacea herb), so they have a similar effect.

Both drugs are used:

1. When initial signs of influenza or colds occur, as well as for the prevention of these pathologies;
2. In order to improve the immune status during long-term treatment with antibiotics;
3. In the treatment of recurrent genitourinary and respiratory pathologies.

Echinacea is contraindicated in case of autoimmune pathologies, immunodeficiency (HIV), AIDS, multiple sclerosis, hypersensitivity to the plant and its components, children under 12 years of age, in the presence of systemic pathologies such as leukemia, tuberculosis, etc. It is not recommended to take it unless particularly necessary and for pregnant women , because there are no definitive research results on the effect of the drug on the fetus and the course of pregnancy.

Immunal in the form of a solution is contraindicated for children under one year of age, and in tablets for children under 4 years of age. The drug should not be taken if you have autoimmune and systemic pathologies such as AIDS or HIV, multiple sclerosis and leukemia, tuberculosis, etc. Immunal should not be taken by persons who have hypersensitivity or intolerance to echinacea and other components of the drug. Unlike Echinacea, Immunal can be taken by nursing and pregnant women, but only with a doctor's prescription.

Immunomax (800 RUR*)

An effective immunostimulant, under the influence of which there is a threefold increase in the activity of the cellular structures of the immune system. Immunomax increases the body's resistance to viruses like herpes or plague, papillomavirus or parvovirus. In addition, the drug protects the body from bacterial microorganisms such as chlamydia, staphylococci, E. coli, salmonella or mycoplasma, ureaplasma, etc.

Immunomax contraindications:

• Up to 12 years of age;
• Breastfeeding and pregnancy;
• Hypersensitivity to the drug or its individual components.

The drug does not cause any adverse reactions. And in exceptional cases it can be prescribed during pregnancy.

Galavit (tablets RUR 300*, injections RUR 600*)

A modern immunomodulator, which is available in the form of suppositories, tablets and powder for injection solution. The medication has an additional anti-inflammatory effect. Galavit is a synthetic immunostimulant and currently has no analogues. The drug has a broad-spectrum effect:

1. It enhances the production of necessary antibodies;
2. Enhances the production of macrophages, which are distinguished by their ability to eliminate pathogenic pathogens;
3. Increases the production of interferons, which promote resistance to various infections;
4. Has an antioxidant effect;
5. It has hepatoprotective activity, i.e. it protects the liver.

Galavit is contraindicated for use in patients under 6 years of age, nursing, pregnant women, or people intolerant to this medication.

Arbidol (250 RUR*)

An antiviral agent with moderate immunomodulatory activity. The drug is indicated for diseases such as:

• ARVI, severe cases of respiratory diseases complicated by pneumonic or bronchial processes, types of influenza A and B;
• Pneumonic lesions, complex treatment of chronic inflammation of the bronchi, recurrent herpes, pneumonia;
• Restoration and improvement of immune status, prophylactic administration of the drug after surgery;
• In the complex treatment of acute intestinal lesions of rotavirus origin in pediatric patients (over 3 years).

The drug has virtually no contraindications or side effects. It is not prescribed to children under three years of age, as well as to patients hypersensitive to the drug. Among the possible adverse reactions, allergic manifestations are very rarely observed.

Isoprinosine (600 RUR*)

Tablet drug with antiviral and immunostimulating effects. A product of synthetic origin, a purine derivative, used for diseases such as:

1. Papillomavirus, including with lesions of the genital organs and larynx;
2. Various forms of ARVI and influenza;
3. Shingles and chickenpox;
4. Cytomegalovirus;
5. Various modifications of herpesvirus of all types, as well as herpetic keratitis, genital herpetic lesions, etc.;
6. Molluscum contagiosum;
7. Corey;
8. Mononucleosis of infectious origin, etc.

Among the disadvantages of the drug, patients note the presence of adverse reactions in the form of nausea and vomiting syndrome and epigastric pain, itchy sensation on the skin, joint pain and dizziness, sleep disorders and headaches, exacerbations of gout or intestinal disorders. Since the drug causes an increase in urea in the blood, it is contraindicated in cases of urolithiasis, gout, insufficient renal activity and arrhythmia. In addition, Isoprinosine is contraindicated in children weighing less than 20 kg and under 3 years of age.

Imunofan (500 RUR*)

The drug Imunofan is an immunomodulatory drug with hepatoprotective, detoxification, antioxidant and immunostimulating activity. In addition, the drug prevents the occurrence of cellular resistance to antitumor drugs.

The drug is available in the form of injections, rectal suppositories or nasal spray. Imunofan is effective in treating:

• HIV infections;
• Various types of immunodeficiency conditions;
• Papillomavirus;
• Cytomegalovirus;
• Viral hepatitis of various types;
• Herpes;
• In complex antitumor therapy, etc.

The drug is not used in the treatment of children under 2 years of age and pregnant women with a Rhesus conflict with the fetus.

Tiloron (600 RUR*)

The medications Lavomax, Amiksin and Tiloram are analogues, have the same active ingredient (tilorone) and belong to the group of drugs - inducers of interferon synthesis, which have immunomodulatory and antiviral effects. The drugs are produced in tablet form.

1. Lavomax provokes an increase in the formation of antibodies, stimulates bone marrow stem cell structures, and reduces immunosuppressive activity. It is used for herpetic and cytomegalovirus infections, viral hepatitis, respiratory and influenza infections in adult patients. Contraindicated for pregnant women, children and adolescents under 18, and nursing mothers.
2. Amiksin has a similar effect and is able to stop viral reproduction. Can be used in pediatrics from the age of 7, however, it is contraindicated during breastfeeding and pregnancy.
3. Tiloram, like Lavomax, is contraindicated in patients under 18 years of age, pregnant and breastfeeding patients. Adverse reactions sometimes include allergic rashes, slight chills and dyspepsia (digestive disorders).

Timalin (500 RUR*)

The drug is produced in the form of a lyophilisate for the preparation of injection solutions. The active substance of the drug is thymus extract, which is obtained by extracting from the thymus gland of animals.

The drug is effective when it is necessary to restore immune activity. In addition, while taking Timalin, patients experience an improvement in cellular metabolic processes, hematopoiesis is restored and regeneration is accelerated.

Timalin is indicated:

• With a reduced immune status against the background of various types of soft tissue and bone purulent-inflammatory pathologies;
• For infectious lesions of bacterial or viral origin;
• When hematopoietic and immune functions are suppressed due to chemotherapy or radiation treatment of tumor and oncological processes, as well as during long-term antibiotic therapy, etc.

The drug has no contraindications and is not prescribed only to people with hypersensitivity to it. In rare cases, the use of Timalin is accompanied by adverse allergic reactions.

There is an analogue based on the same substance - Taktivin.

Riboxin

It is a metabolic regulator and has antiarrhythmic and antihypoxic activity. As a result of taking the drug, blood circulation in the coronary network is normalized and the energy balance of the heart increases. The active substance is inosine. The drug is used only in adult patients in the treatment of myocardial ischemia and arrhythmia caused by taking cardiac glycosides.

Cytoflavin

A multicomponent preparation containing inosine, succinic acid, vitamins B₂ and PP. Cytoflavin is a metabolic drug that improves tissue nutrition, cellular respiration, and blood circulation. Has anti-ischemic and neuroprotective activity. Produced in tablets and injections, it is used in the treatment of patients of any age. It is not advisable to use in pregnant and lactating patients.

Can pregnant women take it?

Doctors do not have a clear opinion regarding the use of immunomodulators in pregnant women, however, the majority is inclined to believe that they should not be taken. Most of the drugs in this group have been on the pharmaceutical market for a relatively short time, so the long-term side effects of taking them are still unknown.

To increase immunity, it is better for pregnant women to adjust their diet, enriching it with vegetables, herbs and fruits, rationally organize their regime, spend more time walking in the fresh air, etc.

In childhood

In the treatment of children, the use of immunomodulators and adaptogens is justified in the following cases:

• Frequent ARVI, colds and flu;
• In the absence of hyperthermic symptoms during respiratory infections and influenza;
• For sleep disturbances, severe weakness, frequent headaches;
• For food allergies;
• With a noticeable increase in lymph nodes.

Up to 1.5 years of age, immunomodulators are used only in exceptional cases. Older children, strictly according to medical indications, can be given immunomodulators of the interferon group. It is pointless to give specific names of such drugs, because only a pediatrician should prescribe them. As immunostimulants and adaptogens in children, it is better to use natural remedies such as honey, rose hips, garlic or onions, eucalyptus, etc.

General operating principles

Immunomodulatory drugs are intended to balance the level of cellular structures of the immune system in the presence of autoimmune pathologies. These drugs balance the activity of all immune components, if necessary, suppressing their activity or activating it. The action of adaptogens is aimed at increasing the resistance of organic structures to infectious, viral and other types of external influences.

Immunomodulatory drugs are prescribed to patients with serious health problems. There are a number of pathologies against which the body is unable to resist even the simplest infectious lesions. The most famous such pathology is the human immunodeficiency virus. To avoid constant colds and flu with any minor hypothermia, such patients are prescribed immunomodulators.

Premature children also need immunomodulatory therapy, especially when they begin to attend preschool educational institutions. In such a situation, children find themselves in a completely new environment that has its own bacteria and microorganisms, so sometimes during the adaptation period children are prescribed adaptogens, which:

1. Has little effect on nervous system structures;
2. Restore endocrine activity;
3. Accelerate material exchange reactions;
4. Form the body's resistance to adverse external influences;
5. Helps improve performance, tolerance of excessive loads, etc.

At the same time, adaptogenic drugs do not disrupt the processes of normal functioning of the body. They are recommended to be taken by workers in hazardous industries and hard work, athletes and people in a state of stress or depressive disorder. If you take adaptogens during increased mental and physical stress, the drugs will accelerate the body’s adaptation without harm to brain and muscle activity.

Immunostimulating agents are designed to regulate the body's defenses. Due to a number of diseases, the human immune system does not work properly and does not perform all its functions.

These drugs were invented to help the body’s immune system self-heal. Many of the immunomodulatory drugs have an antiviral effect, and most often they are prescribed when a person suffers from ARVI several times a year.

It should be noted that medical practitioners treat immunomodulators differently. Some see good use in them, while others consider their use useless. You can also find different opinions among patients. To evaluate these drugs, let's look at the most popular immunomodulatory drugs today.

Effective immunomodulatory agents

Lycopid

The drug is used in complex treatment regimens for patients. The main indications for its use are: viral hepatitis, herpes, various secondary immunodeficiencies, purulent-inflammatory processes, tuberculosis, psoriasis and others.

The medicine has a powerful effect, therefore it is indicated for both treatment and prevention. Lykopid has cytotoxic activity, exhibits bactericidal properties, and promotes the resorption of small tumors.

1. The drug is available in tablets. The course of treatment depends on the severity of the disease.
2. In pediatric practice, Likopid is recommended for use from the age of three. In some cases, under the supervision of a doctor, the drug can be used for a child starting from one year of age.
3. In pediatrics, only one dose is allowed - 1 mg per day. For adults, the dose of the drug can vary, reaching up to 20 mg per day.

Pregnancy and lactation are contraindications for use.

The price for Lykopid (1 mg tablets No. 10) is around 230 rubles. For a dosage of 10 mg No. 10 you will have to fork out more; the cost for such a lycopid will be about 1,700 rubles.

Immunal

Immunal contains echinacea. The plant has antiviral, antibacterial, regenerating and anti-inflammatory effects.

Immunal is prescribed for influenza, ARVI, herpes, gynecological problems, and secondary immunodeficiencies. In minimal doses it is used to maintain normal immune function.

Contraindications to the use of Immunal are:

• tubinfection,
• rheumatoid arthritis,
• leukemia,
• allergic reactions,
• various systemic pathologies.

During pregnancy and lactation, the drug is acceptable in extreme cases.

Immunal is produced in tablets, drops, powder, and solution. The doctor selects the necessary form for treatment or prevention.

The price for Immunal (Slovenia) in tablets (No. 20) is 300-350 rubles.

Drops are offered for the youngest patients (from 12 months). Tablets are recommended no earlier than 4 years of age. Some pediatricians believe that it is preferable to use immunostimulating drugs in tablets only after 12 years. Dosing of the drug is carried out according to the instructions.

Kagocel

The drug has antiviral and immunomodulatory effects. Kagocel is similar in action to interferon. It is used to treat ARVI and herpes. Recommended for use from the age of three. The plus of Kagocel is the minimal possible side effects (individual intolerance and allergic reactions).

Depending on the age and disease, the dose of the drug varies.

Kagocel (Russia) is available in tablets. The price per package (No. 10) is an average of 260 rubles. A course of treatment usually requires 10-18 tablets. Treatment of herpes will cost more, approximately 780 rubles.

Viferon

This drug acts comprehensively. The active substance is human recombinant interferon alpha-2. The product has the following properties: immunomodulatory, protective, antiviral, antiproliferative.

The range of applications for Viferon is quite diverse. These are ARVI, viral lesions of mucous and skin surfaces, stenosing laryngotracheobronchitis (in complex therapy), herpes, viral hepatitis, HIV, bronchial asthma, and others.

Viferon has also found widespread use in pediatrics. It is used even in newborns and premature babies.

Depending on the form of the drug, the dose of Viferon has its own characteristics. For example, suppositories are used 1-2 times a day, and gel up to 5 times a day.

The price for Viferon is as follows:

• gel 36000IU/ml 10ml costs about 180 rubles;
• suppositories 1000000IU (No. 10) - 520 rubles;
• ointment 40000IU/g 12g - 180 rubles.

In principle, Viferon can be classified as an inexpensive drug, which makes it popular among patients.

Amiksin

This drug, like many drugs with antiviral and immunomodulatory properties, is an inducer of interferon synthesis. It is used for liver diseases, acute respiratory viral infections, tubinfection and other diseases. It has been noted that amiksin is useful for urological, gynecological and neuroinfections.

The dosage of the drug is determined only by the doctor, because amixin is prescribed differently depending on the day of therapy.

Amiksin has few side effects: allergic reactions, chills, diarrhea.

In pediatrics, the drug is used only from the age of seven. The drug is not prescribed to pregnant women and persons with individual intolerance to the composition of amixin.

Tablets of 60 or 125 mg are available. The price of tablets (60 mg, No. 10) is 550 rubles.

Cycloferon

The drug is an inducer of endogenous interferon. Exhibits antiviral, immunomodulatory, antitumor, anti-inflammatory effects. Cycloferon reduces the content of carcinogens in the blood and also helps slow down metastatic processes in malignant neoplasms.

The effectiveness of cycloferon has been proven for hepatitis, HIV, ARVI, herpes, enteroviruses, chlamydia, tick-borne encephalitis and other infections. In systemic diseases, cycloferon exhibits moderate analgesic and anti-inflammatory effects.

The method of application depends on the severity of the infectious process (the instructions for use should be followed).

Contraindications: individual intolerance, allergies, pregnancy, lactation and liver cirrhosis. In pediatrics, the drug is used from 4 years of age.

Cycloferon is available in tablets, liniment and solution for injection. The price, respectively, is 190 rubles (10 tablets), liniment - 105 rubles, ampoules (5 pieces) - 330 rubles.

Thymogen

The drug belongs to the drugs that correct and stimulate the immune system.

The basis of thymogen is glutamine tryptophan. Immunodeficiency states are indications for prescribing this drug. No special contraindications or side effects were found.

Thymogen has three dosage forms: aerosol, injection solution, cream for external use.

The price of the drug depends on the dosage form. Injection solution 0.01% 1 ml No. 5 costs about 330 rubles. The price of cream for external use 0.05% 30g ranges from 270 to 330 rubles. Aerosol 0.025% 10 ml costs about 310 rubles.

Derinat

This drug has established itself as a powerful immunomodulator. The range of its applications is huge. These are oncological processes, chronic gastrointestinal diseases, cardiac pathologies, tubinfection, gynecological and urological infections.

Derinat activates all parts of the immune system and also stimulates regenerative processes. Thanks to derinat, tissue regeneration occurs faster, so this product is prescribed for the treatment of burns and ulcerative processes on the skin.

Dystrophic problems in eye diseases are eliminated faster when taking Derinat.

A big advantage of this remedy is the possibility of its use from the first days of a child’s life, when many medications are contraindicated.

Derinat is available in solution for injection or solution for local and external use.

The course of treatment depends on the disease and can range from 5 to 45 days. In any case, derinat treatment is not carried out independently.

A solution of 0.25% 10 ml for topical use costs about 300 rubles, a solution for injection 1.5% 5 ml No. 5 - 2000 rubles.

Anaferon

The effectiveness of anaferon has been observed in acute respiratory viral infections, bronchopulmonary pathologies, herpes infections, as well as other diseases caused by viral agents. Anaferon is a safe homeopathic drug with high antiviral protection. Bacteria, like viruses, also lose their strength thanks to the “work” of anaferon. Diseases with chronic immunodeficiency are a direct indication for this drug.

Like other immunomodulators, anaferon should not be used during gestation, but if particularly necessary, it can be used in the second and third trimester of pregnancy. This is due to the fact that after the 12th week of pregnancy the fetus is already more protected. The embryonic period passed, the placenta became thicker, and the unborn baby began to gain more body weight.

In pediatrics, anaferon is used once a day. As a rule, the course of treatment lasts a week. The pharmacy chain sells Anaferon for children (in drops and tablets). The form of the drug for therapy is selected by the doctor.

The price for children's and adult anaferon in lozenges (20 pieces) is about 200 rubles, in drops (25 ml) a little more expensive - 250-300 rubles.

Cheap analogues of Anaferon - list.

Lysobacter

The drug is popular in otolaryngology and dentistry. It is based on two active components - lysozyme and vitamin B6. The first fights infection, the second protects the mucous membrane. Despite the fact that lysobact is an antiseptic, its effectiveness in the fight against viruses has been proven more than once. The immunomodulatory effect of lysobact is weak, so it can be safely used during gestation and lactation.

Lysobact is prescribed for infections and inflammation of the pharyngeal space, stomatitis, gingivitis, aphthous ulcerations, and herpes.

Side effects while taking lyzobact appear extremely rarely. Only mild allergic reactions are possible.

The course of treatment lasts about 8 days. The tablets are dissolved slowly under the tongue (sublingually). It is advisable to keep the dissolved mass under the tongue for as long as possible and refrain from eating food and water for several hours.

Tablets are used from 3 to 8 pieces per day. Children from 3 to 7 years old are recommended to take 1 tablet three times. For adults, the following dosage is recommended - 2 tablets 4 times a day.

The price of lyzobact (Bosnia and Herzegovina) No. 10 is 250-320 rubles.

Remantadine

Conclusion

Analyzing our article, it is easy to notice that many drugs have much in common. This is especially true for indications for use. To date, there is still a lot of controversy regarding the use of immunomodulators. There are opinions that the body itself is capable of recovering, and immunomodulators act only as a placebo.

Immunomodulators are now very popular - they improve the body’s protective function and are intended for adults and children. But these medications must be used wisely: improper use can cause serious harm to a person. In this article, the reader will learn how immunomodulators affect the body of adult women and men, including children. The text contains the characteristics of specific drugs and reviews of people who assessed their effects, which are freely available on various Internet sites.

What kind of immunomodulator medicine is this and what effect does it have?

A person can be congenital or acquired. The first type of defense is depleted very quickly and is not able to resist the pathogen for a long time. The acquired one is activated after the innate resources are exhausted; it has memory: in many cases, having once had an illness, a person tolerates re-infection more easily, because the acquired immunity has remembered an effective antibody to a given pathogen.

Attention! This principle is used in vaccination, when a weakened pathogenic microorganism is injected into a person, allowing the immune system to analyze the pathogen and develop effective protection.

When the body is unable to cope with the disease, immunomodulators are used. These are drugs that change the characteristics of the human immune system. There are 2 groups of immunomodulators:

• immunostimulants– force the defense system to act more actively;
• immunosuppressants has a depressing effect on the immune system, lowering it.

There is a difference between immunomodulators and immunostimulants: the former contain useful substances that help a person’s defenses overcome the disease, strengthen it, while stimulants artificially activate the immune system, forcing the use of internal reserves to fight.

The following groups of diseases can be distinguished for the treatment of which immunomodulators are used:

• chronic infections;
• allergy;
• tumors;
• immunodeficiency ().

Attention! Immunosuppressants are needed when the immune system malfunctions, causing it to act against its own body.

Reception and treatment with immunomodulators occurs when a doctor prescribes complex treatment, when the patient takes different groups of medications: antibiotics, antivirals and other drugs. This combination increases the body's defenses during active therapy.

These funds can also be used to speed up the patient’s rehabilitation period. After a course of administration, their effect continues for a long time, up to several years.

Classification of drugs, immunomodulators for children

These drugs, immunomodulators, are divided into 3 groups:

1. Endogenous– synthesis of substances occurs in the body itself.
2. Exogenous– all necessary substances and compounds come from outside with the intake of plant substances and beneficial bacteria.
3. Synthetic- completely artificial drugs.

We can distinguish herbal immunomodulators for adult women and men: many of them are used in traditional medicine recipes; since ancient times, people have discovered the healing properties of some plants. Among them, two groups can be distinguished:

• aggressive;
• soft.

The first group of plants has a more complex composition and is capable of inhibiting the defense system if used incorrectly. This group includes: licorice, yellow egg capsule, mistletoe and etc.

The second group is broader in composition; these plants help the immune system without side effects. This ginseng, Aralia, nettle, thyme, pine and nuts, garlic, figs etc.

Attention! The second group of medications can be recommended for self-medication (according to prescriptions), the first - only after consultation with a doctor and under his supervision.

It is necessary to give immunomodulators to a child very carefully, since the child’s defense system is at the stage of formation. Unreasonable use of immunomodulators and their active substances can lead to suppression of the child’s immunity.

Children over 6 years old are allowed to give immunomodulatory drugs no more than twice a year; children under 2 years old can use them only under the supervision of a doctor in difficult situations.

There are different points of view regarding the possibility of using various immunomodulators in children; for example, Dr. E. Komarovsky, a famous children's doctor, believes that children should not be given immunomodulators - this can lead to abnormal development and inability to protect themselves from the disease. Each parent is free to have their own point of view, but it is recommended to analyze all the pros and cons in advance.

You need to remember the main thing: the use of these medications, immunomodulators, immunostimulants or immunosuppressants, is possible only after consultation with a specialist. For both children and adults, it is possible to obtain a beneficial effect from taking immunomodulators only by selecting the right dose and taking into account the specific characteristics of a person’s health.

Improper use of immunomodulators can lead to a significant weakening of the immune system; in some situations, their use is contraindicated - for example, in the presence of autoimmune diseases, drugs can cause unpredictable and even fatal consequences.

The use of immunomodulators in the treatment of various diseases

1. . It is a viral disease, the causative agent of which is present in almost every person in a passive form. When comfortable conditions arise (the development of other diseases, weakening of protection), the virus begins to manifest itself as a pathogen, causing the development of the disease. Immunomodulators are used, among which the most effective are drugs from the group of interferons and certain nonspecific drugs (Cordyceps, natural immunity modulators, etc.). Treatment is most effective with simultaneous vitamin therapy.
2. Cold. Most often, the disease is of a viral nature and is associated with hypothermia. For treatment the following are used:

• antiviral immunomodulators as prescribed by a doctor;
• all natural remedies (as a complementary self-medication).

For colds, immunomodulators are used only in case of a complicated course of the disease, for example, if the high temperature persists for several days and the symptoms of acute respiratory infections do not subside. Only in this case will the attending physician prescribe an intensive course of therapy.

1. Flu. For the treatment of this disease, all natural, herbal immunomodulatory agents are indicated -, cranberry, rose hip, Melissa, . It is possible to use antiviral and anti-inflammatory immunomodulators (, etc.).

Attention! Herbal immunomodulators are allowed to be used only in the absence of contraindications (allergic reactions or concomitant diseases). It is recommended to consult a doctor before use.

1. Immunodeficiency virus (). This is a dangerous pathology that gradually deactivates the human defense system. Despite the fact that immunomodulators cannot eliminate this virus, the drugs can activate the immune system and significantly alleviate the patient’s condition. Medicines are used in conjunction with antiretroviruses and other drugs necessary for HIV-infected people. In addition to synthetic immunomodulators, natural drugs are widely used.

List of effective immunomodulators and reviews

The list of immunomodulators today is quite large and varied.

Interferon

Interferon is an antiviral and antitumor modulator that is synthesized in the body itself. Interferon is used as:

• prophylactic agent for ARVI epidemics. The sooner you start taking a drug from the interferon group, the better the body will resist the effects of pathogens;
• to restore the body, immune system, after serious illnesses.

It is in the ranking of the most effective drugs for strengthening the immune system. The most common form of interferon release is ampoules with powder, which must be diluted with water and dropped into the eyes and nose. Also available in the form of rectal suppositories and for intramuscular injections.

Reviews of the use of Interferon:

“Interferon” perfectly increases the body’s defenses, I can say this from my husband and I’s experience. I bought it as prescribed by a doctor in the form of a dry powder in ampoules. The important thing is that you should not dilute the medicine too much, because the medicine is stored in the refrigerator for only a couple of days. This is a very good antiviral immunomodulator, protects against influenza and ARVI. It is better to use only after consulting a doctor: there are contraindications.

Anastasia, 29 years old

Not everyone talks about this, but Interferon cannot be used constantly. Yes, he helped me quickly get my child on his feet. Having seen such a miraculous effect, I instilled the drug in him every day, and when I stopped it in the spring, he immediately fell ill. It turns out that if you give the medicine for a long time, it will suppress the immune system, preventing the body from synthesizing its own interferon. So this medicine needs to be taken in moderation.

Ira, 35 years old

There are restrictions on the use of the immunomodulator Decaris for pregnant women, for example, when taken during lactation, breastfeeding is prohibited.

Children over 3 years old can use Decaris in strictly dosed doses. The cost is about 75 rubles per pack with one Dekaris tablet.

Reviews of the use of Decaris tablets:

Kirill 34 years old

Anton, 33 years old

Lycopid

In the photo, Likopid tablets are a strong immunomodulator and immunostimulant for adults and children.

Lykopid is a powerful immunomodulator and immunostimulant. Likopid is effective in the treatment of purulent-septic infections. Due to its bactericidal activity, Lykopid can be used as an antitumor drug, and is also used during therapy:

• psoriasis and other skin diseases;
• eye infections;
• hepatitis (infectious).

Attention! Likopid is considered a very strong drug, so it must be taken in doses; it is contraindicated during pregnancy and breastfeeding.

Lykopid® - instructions for use

Release form, composition and packaging White, round, flat-cylindrical tablets, with a chamfer and a score. 1 tab. glucosaminylmuramyl dipeptide (GMDP) 10 mg Excipients: lactose monohydrate – 184.7 mg, sugar (sucrose) – 12.5 mg, potato starch – 40 mg, methylcellulose – 0.3 mg, stearate – 2.5 mg. 10 pieces. – blister contour packages (1) – cardboard packs. Pharmacological action Pharmacodynamics The active substance of Lykopid® tablets is glucosaminylmuramyl dipeptide (GMDP) - a synthetic analogue of the structural fragment of the membrane (peptidoglycan) of bacterial cells. GMDP is an activator of innate and acquired immunity, strengthens the body’s defense against viral, bacterial and fungal infections; has an adjuvant effect in the development of immunological reactions. The biological activity of the drug is realized through the binding of GMDP to the intracellular receptor protein NOD2, localized in the cytoplasm of phagocytes (neutrophils, macrophages, dendritic cells). The drug stimulates the functional (bactericidal, cytotoxic) activity of phagocytes, enhances their presentation of antigens, the proliferation of T- and B-lymphocytes, increases the synthesis of specific antibodies, and helps normalize the balance of Th1/Th2 lymphocytes towards the predominance of Th1. The pharmacological action is carried out by enhancing the production of key interleukins (interleukin-1, interleukin-6, interleukin-12), TNF alpha, interferon gamma, colony-stimulating factors. The drug increases the activity of natural killer cells. Likopid® has low toxicity (LD50 exceeds the therapeutic dose by 49,000 times or more). In the experiment, when administered orally in doses 100 times higher than the therapeutic dose, the drug does not have a toxic effect on the central nervous system and cardiovascular system, and does not cause pathological changes in internal organs. Likopid® does not have embryotoxic or teratogenic effects and does not cause chromosomal or gene mutations. Experimental studies conducted on animals provided data on the antitumor activity of the drug Lykopid® (GMDP). Pharmacokinetics The bioavailability of the drug when taken orally is 7-13%. The degree of binding to blood albumin is weak. The time to reach Cmax is 1.5 hours after administration. T1/2 – 4.29 hours. Does not form active metabolites, is excreted mainly through the kidneys unchanged. Indications The drug is used in adults in the complex treatment of diseases accompanied by secondary immunodeficiency states: - acute and chronic purulent-inflammatory diseases of the skin and soft tissues, including purulent-septic postoperative complications; - sexually transmitted infections (human papillomavirus infection, chronic); - herpetic infection (incl. with ophthalmoherpes); - psoriasis (including psoriatic); - lungs. Dosage regimen Licopid® is administered orally on an empty stomach, 30 minutes before meals. Elderly patients are recommended to start treatment with half doses (1/2 of the therapeutic dose), in the absence of side effects, increasing the dose of the drug to the required therapeutic dose. If a drug dose is missed, if no more than 12 hours have passed from the scheduled time, the patient can take the missed dose; If more than 12 hours have passed from the scheduled time of administration, you must take only the next dose according to the schedule and not take the missed one. Purulent-inflammatory diseases of the skin and soft tissues, acute and chronic, severe, including purulent-septic postoperative complications: 10 mg 1 time / day for 10 days. Herpetic infection (recurrent course, severe forms): 10 mg 1 time / day for 6 days. For ophthalmoherpes: 10 mg 2 times a day for 3 days. After a break of 3 days, the course of treatment is repeated. Sexually transmitted infections (human papillomavirus infection, chronic): 10 mg 1 time/day for 10 days. Psoriasis: 10–20 mg 1 time/day for 10 days and then five doses every other day, 10–20 mg 1 time/day. For severe psoriasis and extensive lesions (including psoriatic): 10 mg 2 times a day for 20 days. Pulmonary tuberculosis: 10 mg 1 time/day for 10 days. Side effects Often (1–10%) – arthralgia (joint pain), myalgia (muscle pain); at the beginning of treatment, there may be a short-term increase in body temperature to subfebrile values ​​(up to 37.9°C), which is not an indication for discontinuation of the drug. Most often, the side effects described above are observed when taking Lykopid® tablets in high doses (20 mg). Rarely (0.01-0.1%) – a short-term increase in body temperature to febrile values ​​(>38.0°C). If body temperature rises >38.0°C, antipyretics can be taken, which does not reduce the pharmacological effects of Lykopid® tablets. Very rarely (<0.01%) – . Если любые из указанных в инструкции побочных эффектов усугубляются или пациент заметил любые другие побочные эффекты, следует сообщить об этом врачу. Противопоказания к применению - повышенная чувствительность к глюкозаминилмурамилдипептиду и другим компонентам препарата; - беременность; - период лактации (грудного вскармливания); - детский возраст до 18 лет; - аутоиммунный тиреоидит в фазе обострения; - состояния, сопровождающиеся фебрильной температурой (> 38°C) at the time of taking the drug; - rare congenital metabolic disorders (alactasia, galactosemia, lactase deficiency, lactose intolerance, sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption); - use for autoimmune diseases is not recommended due to the lack of clinical data. Likopid® 10 mg is used with caution in elderly people, strictly under the supervision of a physician. Use during pregnancy and breastfeeding Taking Licopid® 10 mg is contraindicated for women during pregnancy and breastfeeding. Special instructions When starting to take the drug Likopid® 10 mg, there may be an exacerbation of the symptoms of chronic and latent diseases associated with the main pharmacological effects of the drug. In elderly people, Licopid® 10 mg is used with caution, strictly under the supervision of a physician. Elderly patients are recommended to start treatment with half doses (1/2 of the therapeutic dose), in the absence of side effects, increasing the dose of the drug to the required therapeutic dose. The decision to prescribe Licopid® tablets 10 mg to patients with a combination of diagnoses of psoriasis and gout should be made by a doctor when assessing the risk/benefit ratio, due to the potential risk of exacerbation of gouty arthritis and joint swelling. If the doctor decides to prescribe the drug Likopid® tablets 10 mg in a situation where the patient has a combination of diagnoses of psoriasis and gout, treatment should begin with low doses, in the absence of side effects, increasing the dose to a therapeutic one. Each Licopid® 10 mg tablet contains sucrose in the amount of 0.001 XE (bread units), which should be taken into account in patients with. Each Licopid® 10 mg tablet contains 0.184 grams of lactose, which should be taken into account by patients suffering from hypolactasia (lactose intolerance, in which the body experiences a decrease in the level of lactase, the enzyme necessary to digest lactose). Influence on the ability to drive vehicles and operate machinery. Does not affect the ability to drive vehicles and complex mechanisms. Overdose Cases of drug overdose are unknown. Symptoms: based on the pharmacological properties of the drug, in case of overdose, a rise in body temperature to subfebrile (up to 37.9 ° C) values ​​may be observed. Treatment: if necessary, symptomatic therapy (antipyretics) is carried out, sorbents are prescribed. A specific antidote is unknown. Drug interactions The drug increases the effectiveness of antimicrobial drugs, and there is synergism with antiviral and drugs. Antacids and sorbents significantly reduce the bioavailability of the drug. GCS reduce the biological effect of the drug Likopid®. Conditions and periods of storage The drug should be stored in a dry place, protected from light, out of reach of children at a temperature not exceeding 25°C. Shelf life – 5 years. Do not use after expiration date. Conditions for dispensing from pharmacies The drug is dispensed with a prescription.

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Reviews of the use of tablets immunomodulatorLycopid:

I have low immunity, and the doctor prescribed me the immunomodulator “Likopid”. The medicine is sold in tablets, the price is high, and this is the only disadvantage. The effect does not appear immediately, the effect is cumulative. I took three courses, only after that I noticed that my immunity had become stronger - I endured the cold autumn and winter calmly, and never got sick, which is an amazing and rare occurrence for me!

Anna, 37 years old

At first, my relationship with this immunomodulator did not work out. When I started taking the medicine prescribed to me, I did not find any positive effect. After some time, I took another course of Lykopid, and began to feel that my health began to improve. Then I learned from the doctor that the drug does not act immediately, first the medicinal substances accumulate, and only then they strengthen the immune system. This happened in my case too; I haven’t been sick during the cold season for several years now.

Oleg, 43 years old

Arbidol

® – proven protection against colds and flu!

is an antiviral drug with moderate effects. Arbidol is used as a therapeutic and preventive measure for severe viral diseases (acute respiratory infections, influenza, bronchitis, etc.).

I have a large family, and every year we use Arbidol to prevent influenza and ARVI diseases. Capsules for children and adults with different dosages are sold - this is a big plus, because you want to protect children without side effects. We use it as a preventive measure, the effect is good - none of the family members have gotten sick in two years. The drug is inexpensive - this is also a plus, it helps to avoid both the disease itself and expensive treatment.

Olga, 40 years old

"Arbidol", of course, is a well-known and time-tested medicine. About ten years ago, my doctor recommended that I use this immunomodulator for prevention, and make it a rule. During all this time I have never regretted this advice. Now this is my little tradition: when autumn comes, I go to the pharmacy and take Arbidol! By the way, I get sick very rarely.

Innocent, 39 years old

Amiksin

Amiksin is a powerful antiviral and immunomodulatory agent.

Amiksin is an antiviral drug with a strong effect. The immunomodulator Amiksin is used in the treatment of hepatitis A, B, C and various viral infections, including influenza, acute respiratory infections, and pulmonary diseases. Children can take Amiksin no earlier than 7 years old - the effect is powerful; before this age can have a destructive effect on the developing immune system.

Reviews of the use of Amiksin tablets:

I live in the south of Russia, where the climate is mild; I once went to visit relatives in Yaroslavl in winter and almost immediately fell ill. High temperature, weakness - in a word, flu. Within an hour after taking the first Amiksin tablet, the temperature almost returned to normal, and three days later I forgot about the illness! But it must be remembered that the medicine is strong, children should be given only a small dosage and consult a doctor first.

Antonina, 41 years old

I became acquainted with this immunomodulator almost two years ago, when I was sick several times in winter and spring. At this time I had to travel around the country in connection with my work. The infection hit me powerfully and knocked me off my feet. A friend bought the drug after consulting with the seller at the pharmacy. I took only three tablets and was cured of the disease! Already on the second day I felt so healthy that I was able to return to work. Then I found out that this drug is contraindicated for those who are allergic to the constituent substances. But Amiksin really helped me!

Nikolay, 49 years old

Amiksin - instructions for use

Release form, composition and packaging Orange film-coated tablets, round, biconvex; on the cross section - the core is orange, minor darker or lighter inclusions are allowed. 1 tab. tilorone (tilaxin) 125 mg Excipients: potato starch - 46 mg, microcrystalline cellulose - 120 mg, povidone (povidone K30) - 3 mg, stearate - 3 mg, croscarmellose (croscarmellose sodium) - 3 mg. Shell composition: hypromellose (hydroxypropyl methylcellulose) – 6.81 mg, titanium dioxide – 3.563 mg, macrogol (polyethylene glycol 4000) – 0.913 mg, polysorbate 80 (Tween 80) – 0.114 mg, quinoline yellow dye (E104) – 0.247 mg, sunset yellow dye (E110) – 0.353 mg. 6 pcs. – blister contour packages (1) – cardboard packs. 6 pcs. – blister contour packages (2) – cardboard packs. 10 pieces. – blister contour packages (1) – cardboard packs. 10 pieces. – blister contour packages (2) – cardboard packs. 6 pcs. – polymer jars (1) – cardboard packs. 10 pieces. – polymer jars (1) – cardboard packs. 20 pcs. – polymer jars (1) – cardboard packs. Pharmacological action Low molecular weight synthetic interferon inducer that stimulates the formation of alpha, beta, gamma interferons in the body. The main structures that produce interferon in response to the administration of tilorone are intestinal epithelial cells, hepatocytes, T-lymphocytes, neutrophils and granulocytes. After taking the drug orally, the maximum production of interferon is determined in the sequence intestine-liver-blood after 4-24 hours. Amiksin® has an immunomodulatory and antiviral effect. Induces the synthesis of interferon in human leukocytes. Stimulates bone marrow stem cells, depending on the dose, enhances antibody formation, reduces the degree of immunosuppression, restores the ratio of T-suppressors and T-helpers. Effective against various viral infections (including those caused by influenza viruses, other pathogens of acute respiratory viral infections, viruses, herpes). The mechanism of antiviral action is associated with inhibition of the translation of virus-specific proteins in infected cells, as a result of which viral reproduction is suppressed. Pharmacokinetics Absorption After taking the drug orally, tilorone is rapidly absorbed from the gastrointestinal tract. Bioavailability is about 60%. Distribution: Binding to blood plasma proteins – about 80%. Metabolism and excretion Tiloron does not undergo biotransformation and does not accumulate in the body. It is excreted almost unchanged in feces (about 70%) and urine (about 9%). T1/2 is 48 hours. Indications In adults - for the prevention and treatment of influenza and ARVI; - for the treatment of viral hepatitis A, B and C; - for the treatment of herpes infection; - for the treatment of cytomegalovirus infection; - as part of complex therapy of allergic and viral encephalomyelitis (including disseminated encephalomyelitis, leukoencephalitis, uveoencephalitis); - as part of complex therapy of urogenital and respiratory diseases; - as part of complex therapy of pulmonary tuberculosis. In children over 7 years of age - for the treatment of influenza and ARVI. Dosage regimen The drug is taken orally after meals. In adults, for nonspecific viral prevention, the drug is prescribed at a dose of 125 mg once a week for 6 weeks. Course dose – 750 mg (6 tablets). When treating a viral infection, the dose of the drug on the first day is 125 mg 2 times a day, then switch to taking 125 mg after 48 hours. The course of treatment is 1.25 g (10 tablets). When treating acute B, in the initial phase of treatment on the first and second days, the dose of the drug is 125 mg/day, and then 125 mg after 48 hours. The course of treatment is 2 g (16 tablets). In case of protracted hepatitis B, on the first day the dose of the drug is 125 mg 2 times a day, then 125 mg after 48 hours. The course dose is 2.5 g (20 tablets). For chronic hepatitis B in the initial phase of treatment, the total dose is 2.5 g (20 tablets). In the first 2 days, the daily dose is 250 mg, then switch to taking 125 mg after 48 hours. In the continuation phase of treatment, the total dose ranges from 1.25 g (10 tablets) to 2.5 g (20 tablets), while the drug is prescribed at a dose of 125 mg per week. The course dose of Amiksin varies from 3.75 to 5 g, the duration of treatment is 3.5-6 months, depending on the results of biochemical, immunological and morphological studies, reflecting the degree of activity of the process. In acute cases, on the first and second days of treatment, Amiksin® is prescribed at a dose of 125 mg/day, then 125 mg after 48 hours. The course dose is 2.5 g (20 tablets). For chronic in the initial phase of treatment, the total dose is 2.5 g (20 tablets). In the first 2 days, the drug is taken at a dose of 250 mg/day, then 125 mg after 48 hours. In the continuation phase of treatment, the total dose is 2.5 g (20 tablets), while the drug is prescribed at a dose of 125 mg per week. The course dose of Amiksin is 5 g (40 tablets), the duration of treatment is 6 months, depending on the results of biochemical, immunological and morphological studies, reflecting the degree of activity of the process. For complex therapy of neuroviral infections - 125-250 mg/day in the first two days of treatment, then 125 mg after 48 hours. The dose is set individually, the duration of treatment is 3-4 weeks. For the treatment of influenza and other acute respiratory viral infections in the first 2 days of illness, Amiksin® is prescribed at a dose of 125 mg/day, then 125 mg after 48 hours. The course dose is 750 mg (6 tablets). To prevent influenza and ARVI, Amiksin® is prescribed at a dose of 125 mg once a week for 6 weeks. Course dose – 750 mg (6 tablets). For the treatment of herpetic, cytomegalovirus infections, the dose of the drug in the first 2 days is 125 mg, then take 125 mg every 48 hours. The course dose is 1.25-2.5 g (10-20 tablets). For urogenital and respiratory infections, Amiksin® is prescribed at a dose of 125 mg/day for the first 2 days, then 125 mg every 48 hours. The course dose is 1.25 g (10 tablets). For complex therapy of pulmonary tuberculosis, in the first 2 days the drug is prescribed at 250 mg/day, then 125 mg every 48 hours. The course dose is 2.5 g (20 tablets). For children over 7 years of age with uncomplicated forms of influenza or other acute respiratory viral infections, the drug is prescribed in a dose of 60 mg (1 tablet) 1 time/day after meals on the 1st, 2nd and 4th day from the start of treatment. Course dose – 180 mg (3 tablets). If complications of influenza and other acute respiratory viral infections develop, the drug is taken 60 mg 1 time / day on the 1st, 2nd, 4th, 6th day from the start of treatment. Course dose – 240 mg (4 tablets). Side effects From the digestive system: symptoms of dyspepsia are possible. Other: short-term chills and allergic reactions are possible. Contraindications for use: pregnancy; - period of breastfeeding; - children under 7 years of age; - increased sensitivity to the drug. Use during pregnancy and breastfeeding Amiksin® is contraindicated for use during pregnancy and breastfeeding. Use in children Contraindication: children under 7 years of age. Special instructions Amiksin® is compatible with antibiotics and traditional treatments for viral and bacterial infections. Overdose To date, cases of overdose of the drug Amiksin® are unknown. Drug interactions No clinically significant drug interactions between Amiksin and antibiotics and traditional treatments for viral and bacterial infections have been identified. Conditions and periods of storage The drug should be stored out of the reach of children, in a dry place, protected from light at a temperature not exceeding 30°C. Shelf life – 3 years. Conditions for dispensing from pharmacies The drug is available without a prescription.

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Lymphomyosot

Lymphomyosot is a strong homeopathic remedy with immunomodulator properties.

Lymphomyosot is a homeopathic remedy with immunomodulator properties. Lymphomyosot improves the absorption of all medications, in many cases making it possible to reduce their dosage and prevent side effects. Lymphomyosot also fights edema well, has a lymphatic drainage effect, normalizing the exchange of fluids in the human body.

In addition to the effect of activating metabolic processes and strengthening the ability of the immune system to resist, Lymphomyosot removes harmful chemical compounds from the body. Used to treat diseases of the ENT organs, skin diseases, tumors, asthenia, etc.

Lymphomyosot is contraindicated in the presence of diseases of the thyroid gland and liver.