Is it possible to take calcemin? Calcemin tablets - instructions for use. Use during pregnancy and breastfeeding

With age, the body's ability to recover decreases, and bone tissue activity decreases. Timely intake of Calcemin tablets preserves health for many years. The treatment restores bone tissue without harm to health and prevents the development of osteoporosis in older people. However, in large quantities the drug harms the body and increases the risk of a heart attack by 80%.

Components and mechanism of action

The composition of the drug is selected in such a way that the trace element is deposited exactly where it is needed. One tablet contains citrate and calcium carbonate in a dose of 0.25 g. Additional substances do not affect the amount and concentration of gastric juice, are safe to use and rarely cause side effects.

Cholecalciferol eliminates vitamin D3 deficiency in the patient’s body and promotes the growth of bone cells. The active substance in Calcemin normalizes the function of the parathyroid glands.

In case of diseases of the musculoskeletal system, thanks to the use of medicine, the whole body is healed. Zinc in a safe and effective dose has an effect on bone tissue, has a regenerating and antioxidant effect, and ensures the production of the hormone testosterone.

Kalcemin tablets contain 2 important chemical elements - boron and copper. Manganese is involved in the synthesis of bone and cartilage tissue. The activity of parathyroid hormones depends on the presence of boron. The trace element prevents the accumulation of calcium in internal organs.

Price

The price of the drug depends on the form of release and the brand of the manufacturer. Calcemin No. 30 costs 389 rubles, and No. 60 costs 699 rubles.

Usage diagram

To restore bone tissue and replenish reserves of valuable microelements, the patient will need instructions for using the drug. Calcemin can be taken by children at least 5 years old with severe symptoms of the disease. Treatment must be agreed with your doctor.

The tablets are taken before meals or with food. The dose of the drug recommended for 1 dose should not be ignored.

The medicine Kalcemin Advance is an excellent remedy for the treatment and prevention of osteoporosis. Adult patients take it 1 tablet per day, preferably after meals. To replenish calcium reserves, diet adjustments are made. It is better to take the medicine in the recommended dose along with a good diet; the menu must include a sufficient number of dishes containing:

• zinc;
• oysters;
• pumpkin seeds;
• celery;
• parsnip;
• herring;
• beef;
• liver.

It is necessary to eat enough soy products. When studying the instructions, you should pay attention to the country that produces the medicine.

The manufacturer of the drug Kalcemin-Silver recommends taking the medicine 2 tablets in several doses, but to compensate for calcium deficiency, a single dose may be 2 times less than the recommended one.

In what cases is the drug taken?

To restore bone tissue and reduce the incidence of fractures in osteoporosis, the drug Calcemin Advance is prescribed. Indications for use contain comprehensive information about treatment with the drug at a dose of 2500 mg/day in the following cases:

• use of immunosuppressants;
• fracture therapy;
• exacerbation of joint diseases,
• vitamin deficiency in children and adolescents.

Calcemin will be beneficial only if the patient maintains a water regime and reduces the consumption of table salt. The patient is often recommended to take it, because it contains much more calcium and vitamin D than its analogues.

For fractures, the drug strengthens bone tissue. The doctor insists on taking the medicine Calcemin Advance in case of a complex fracture of the leg bones.

The deficiency of a valuable microelement is especially acute in adolescence. Your doctor or trainer will tell you how to take Calcemin during intense sports training. In bodybuilding and fitness, this valuable mineral is of paramount importance, as it improves muscle function and reduces the duration of stress, which often occurs during sports training.

Restrictions on use

The tablets must be taken in the dose indicated in the instructions. In patients who took the drug in excess of the norm, mortality from heart and vascular diseases exceeds the average by 1.5 times.

Contraindications to the use of Calcemin:

• high content of trace elements in blood serum;
• diseases of the stomach and intestines;
• urolithiasis disease;
• hypersensitivity to the components of the drug.

In renal pathology, drug therapy leads to the development of calcification in the coronary arteries in patients on hemodialysis. In most cases, the clinical outcome of the disease is unfavorable.

Kalcemin is prescribed with great caution to patients suffering from chronic circulatory failure. An absolute contraindication to the use of the drug is its excretion in urine in amounts exceeding 300 mg/day. Calcifications in the kidneys increase the likelihood of developing urolithiasis. You should not take the medicine if the patient has bone metastases, if myeloma or sarcoidosis has progressed.

Concomitant effects of the drug

Often, taking the drug causes harm to a person’s health, his condition worsens, the disease drags on and cannot be avoided without special treatment. Very often the patient experiences side effects:

• nausea;
• vomit;
• bloating;
• allergic reactions;
• increased calcium levels in the blood serum.

A common complication is an excess of microelement in the body, which occurs when taking Calcemin uncontrolled. The patient complains of the following symptoms:

• spastic constipation;
• dizziness;
• nausea;
• vomiting;
• dry mouth;
• convulsions;
• weight loss.

The patient's behavior changes significantly, and symptoms of depression appear. The patient is bothered by brain fog, hallucinations, and insomnia.

Simultaneous use of the drug and alcohol abuse lead to hypocalcemia. The patient develops disturbances in the functioning of the heart, the walls of large coronary vessels and capillaries become thinner, blood clotting is impaired, and in women the level of sex hormones - estrogens - decreases.

Calcemin for fractures and osteoporosis

Osteoporosis is accompanied by changes in the structure of bone tissue; in the photo you can see pathology that is focal in nature at the initial stage of the disease. Calcium and regular movement allow the patient to restore lost mobility of the lumbar vertebrae and increase the amount of trace elements in bone tissue. The course of medication depends on the age and gender of the patient, concomitant diseases, and the degree of tissue destruction.

In case of a fracture, it is recommended to take Calcemin 1 tablet in the morning and evening. Treatment after a femoral neck injury is long-term and complex, but its typical complication, coxarthrosis, is much more dangerous. Therapy intended for joints is restorative in nature, aimed at preventing complications.

Calcemin will not cause harm to the patient’s body if the recommended dosage is not exceeded. For better absorption of the medicine, a course of treatment with the drug is prescribed.

Fracture therapy with calcium preparations is a reliable means for restoring damaged bone tissue. An excellent result can be obtained if you combine calcium intake with massage and physical therapy.

Exceeding the permissible dose

Treatment of the disease requires strict adherence to the rules for taking the medication. An overdose of Calcemin occurs as a result of a frivolous attitude to treatment, when the patient does not think about the possible consequences.

The patient needs to know the risk factors for exceeding the permissible dose of the drug:

• individual characteristics of the body;
• severe concomitant diseases;
• use of incompatible medications;
• mental disorder;
• low social status of the patient.

Overdose symptoms appear some time after taking a large dose of the drug. The patient complains of nausea, vomiting, constipation, dizziness, arrhythmia, and urination problems.

An overdose of a drug can be caused by erroneous administration of the drug by children aged 1 to 5 years. If a serious condition develops - toxic coma - the child is hospitalized in the intensive care unit.

Impaired renal function depends on the effect of the drug on the parenchyma of the urinary organ and the development of toxic-allergic manifestations. The manufacturer of Calcemin indicates in the instructions the maximum single and daily dose, so the patient should be extremely careful when taking the medicine to prevent poisoning.

Use during breastfeeding

It is unacceptable to self-medicate during this crucial period for mother and child. In any case, before starting therapy, you must consult your doctor, carefully read the instructions, which indicate whether the drug belongs to a particular group of drugs or where the manufacturer informs that the drug cannot be used during breastfeeding.

You should not take large doses of Calcemin to prevent joint disease, even if the mother has a concomitant pathology. If the doctor has prescribed drug treatment, it is necessary to consult about the possible development of adverse consequences for the child.

Throughout the entire period of breastfeeding, measures should be taken to reduce the risk of exacerbation of joint disease. If treatment with Calcemin is necessary, you should avoid combining it with other medications. It is important to avoid taking a large dose of the drug once, because it may harm the baby.

Calcemin helps the patient move easily and freely, strengthens bones, and gives healthy joints.

The drug Kalcemin Advance is a vitamin and mineral complex that affects the preservation of phosphorus-calcium balance in the body.

It reduces the risk of developing osteoporosis and other diseases of the musculoskeletal system, replenishes calcium deficiency in adolescents, and strengthens musculoskeletal tissue. The medication is not considered a drug. It belongs to the group of preventive vitamin preparations.

On this page you will find all the information about Kalcemin Advance: complete instructions for use for this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews from people who have already used Kalcemin Advance. Would you like to leave your opinion? Please write in the comments.

Clinical and pharmacological group

A drug that affects phosphorus-calcium metabolism.

Conditions for dispensing from pharmacies

Available without a prescription.

Prices

How much does Calcemin Advance cost? The average price in pharmacies is 550 rubles.

Release form and composition

Calcemin Advance is available in the form of oval tablets coated with a pink film. They are packaged in plastic bottles of 30/60/120 pieces. Each package contains one bottle. Sold through the pharmacy chain.

The composition of one capsule of a pharmacological agent is represented by the following components:

1. Vitamin D3 – regenerates and strengthens bone tissue, allows for complete absorption of calcium – 200 IU.
2. Magnesium – restores bones, participates in hematopoiesis and protein production. The substance regulates cardiac activity and has a sedative effect on the nervous system – 40 mg.
3. Calcium is necessary for strengthening bones and the full functioning of the nervous, muscular, and vascular systems. Participates in blood clotting processes – 500 mg.
4. Copper – strengthens all types of connective tissue – 1.0 mg.
5. Zinc – mobilizes the regeneration of all types of tissues, normalizes enzymatic activity – 7.4 mg.
6. Manganese is an essential element necessary for the construction of cartilage and bone tissue, helps in the absorption of calcium - 1.9 mg.
7. Boron – stabilizes metabolism – 250 mcg.

Pharmacological effect

The active ingredients of Calcemin Advance are:

1. Vitamin D (cholecalciferol) promotes adequate calcium absorption and is involved in the processes of regeneration and bone tissue building.
2. Zinc. Participates in the formation of collagen fibers necessary for the renewal of skin epithelial cells. Has an anti-inflammatory effect. Prevents the appearance of early wrinkles. Reduces skin dryness. Eliminates acne. It is a strong antioxidant and immunomodulator. Stimulates the production of serotonin. Improves mental activity. Helps increase potency. Good for the visual organs.
3. Copper is involved in the formation of elastin and collagen. Helps stop the phenomenon of demineralization of bone structures.
4. Boron normalizes the activity of the parathyroid hormone - parathyroid hormone. The latter is involved in the metabolism of calcium, cholecalciferol, phosphorus, and magnesium. The effect of parathyroid hormone on mineral metabolism does not depend on the intake of vitamin D3.
5. Manganese. Strengthens blood vessels. Protects against the damaging effects of free radicals. Accelerates wound healing. Ensures rapid growth of cartilage and accelerates its recovery from damage. Corrects the menstrual cycle, eliminates the manifestations of premenstrual syndrome. Protects against thyroid problems.
6. Calcium, which is part of the drug, is a building component for bone tissue, regulates the permeability of the vascular wall, is involved in the regulation of conductivity in synapses and neuromuscular junctions, is involved in the contractile activity of skeletal and smooth muscles, and is a necessary component for the blood clotting process. Calcium is presented in the preparation as carbonate and citrate salts. Calcium carbonate contains the maximum amount of elemental calcium.
7. Calcium citrate reduces the dependence of the process of calcium bioavailability on the state of the gastrointestinal mucosa, prevents stone formation in the urinary system even with long-term use, and reduces excess production of parathyroid hormone.

Indications for use

1. For prevention.
2. To stop the leaching of calcium due to impaired metabolic processes.
3. For the treatment of osteoporosis, its exacerbations and complications.
4. To accelerate bone healing and fracture healing.
5. To normalize calcium and phosphorus levels during natural or surgical menopause.
6. As a primary remedy for hormone replacement therapy and stimulation of normal bone formation.
7. As one of the means of complex therapy for conditions accompanied by significant depletion of bone tissue.
8. For the treatment and prevention of tooth decay caused by a lack of calcium, their proper development in childhood, and maintenance of the condition.
   For women during the restructuring of the body during premenopause and postmenopause, especially if it is impossible to resort to hormonal therapy.

Contraindications

In some cases, patients should not be prescribed Calcemin Advance. Instructions for use, reviews of such cases include:

• urolithiasis disease;
• hypercalcemia;
• hypercalciuria;
• children under 5 years of age;
• children under 12 years of age (Advance);
• hypersensitivity to the components of the drug.

Use during pregnancy and lactation

During pregnancy and breastfeeding, the use of the drug must be agreed with a doctor.

The daily dose for pregnant women should not exceed 1500 mg of calcium and 600 IU of vitamin D3, because hypercalcemia, which develops against the background of an overdose during pregnancy, can cause defects in the mental and physical development of the child.

In nursing women, it should be taken into account that colecalciferol and its metabolites are excreted in breast milk. This should be taken into account when additionally prescribing calcium and vitamin D3 to a child.

Instructions for use

The instructions for use indicate that Calcemin Advance is taken orally with meals.

1. To improve the consolidation of traumatic fractures, 1 tablet/day is prescribed; The duration of treatment is 4-6 weeks.
2. To compensate for the deficiency of calcium and microelements, adolescents from 12 years of age are prescribed 1 tablet per day; The average duration of treatment is 4-6 weeks.
3. As part of complex therapy for osteoporosis, 1 tablet is prescribed. 2 times a day, for the purpose of preventing osteoporosis - 1 tablet/day. The duration of use of the drug for the prevention of osteoporosis and in complex therapy of osteoporosis is determined by the doctor individually. The average course duration for the prevention of osteoporosis is 2 months; in the treatment of osteoporosis – 3 months.

Side effects

After taking Calcemin Advance, a review of the drug may contain some information indicating the possibility of developing undesirable reactions.

Possible side effects include allergic reactions, flatulence, vomiting and nausea preceding it. The presence of hypercalciuria or hypercalcemia may also be detected. Side effects are possible, but they are very rare.

Overdose

In case of overdose, the following symptoms occur:

1. Dyspeptic disorders (abdominal pain, thirst, vomiting, constipation);
2. Intoxication syndrome (weakness, fainting, headache);
3. Changes in laboratory parameters.

Treatment of overdose:

1. When the first signs of an overdose appear, you should immediately contact a medical facility.
2. Discontinuation of the drug;
3. Detoxification therapy.

special instructions

While taking the medication, you must strictly adhere to the prescribed dosage and course duration. Concomitant use of other vitamin complexes may lead to side effects. This remedy does not affect attention and coordination of movements; it is approved for drivers and people whose work requires attention and concentration. Does not affect human fertility.

Drug interactions

If the use of “Calcemin Advance” (reviews from doctors fully confirm this) is accompanied by other medications, the following principles must be taken into account.

1. When taken simultaneously with vitamin A, a decrease in the toxicity of vitamin D 3 was revealed.
2. When using tetracyclines simultaneously, a three-hour break must be observed.
3. Means for systemic use (hormonal, contraceptive, glucocorticoids) reduce the absorption of calcium ions.
4. Barbiturates, phenytoin, and glucocorticoids reduce the effectiveness of vitamin D 3, and laxative medications reduce its absorption.
5. When taken simultaneously with cardiac glycosides, their toxicity increases. It is advisable to monitor the ECG and general condition.
6. The drug should not be taken with calcium channel blockers and antacids containing aluminum.
7. When taken in combination with thiazide diuretics, the risk of developing hypercalcemia increases many times; when taken with “loop” diuretics, the excretion of calcium by the kidneys increases.

Content

The drug Calcemin is used by children and adults for calcium deficiency and for its prevention. The vitamin preparation has a complex composition and can be used as a biologically active food supplement. From the instructions for use of the medication you can learn about the indications for use, beneficial properties, method of administration and dosage.

Weakened by illness or malnutrition, the body often needs additional vitamins and other useful substances, which include calcium. A lack of microelement leads to serious consequences for the body, for example, a decrease in the strength of bone tissue. To save patients from problems, doctors advise taking courses of the drug Calcemin.

Composition

The tablets are biconvex, oval in shape, scored on one side, and white in color. They are packaged in bottles of 30/60/120 pieces.

pharmachologic effect

The medication has a complex healing effect on the body due to the substances it contains:

1. Vitamin D3 and osteotropic minerals regulate calcium metabolism, maintaining bone strength and structure.
2. Calcium citrate increases calcium absorption and reduces the risk of iron deficiency anemia.
3. Zinc stimulates the synthesis of sex hormones in the glands, which leads to the preservation of youthful bone tissue.
4. Copper is involved in the synthesis of elastin and collagen, which are an important component of connective and bone tissue.
5. Boron inhibits parathyroid hormone, increases calcium absorption, helps eliminate vitamin D3 deficiency, and helps avoid osteoporosis.

Pharmacodynamics and pharmacokinetics

Absorption of the calcium contained in the preparation occurs in the gastrointestinal tract thanks to the enzyme of the intestinal mucosa - calbindin. The microelement is excreted from the body in urine and partly in feces. Vitamin D is well absorbed in the intestines and quickly delivered to bones, adipose tissue, adrenal glands, heart muscle, and gradually turns into inactive metabolites. When eliminated in the bile, it is partially reabsorbed. Zinc is excreted through the intestines and kidneys (10%). Copper and boron are absorbed from the intestines. Copper is excreted in the bile, boron – in the kidneys.

Indications for use

The main consumers of the medicine are people who need to compensate for the lack of calcium and microelements (often children and adolescents). Other indications for use:

1. The drug is used for complex therapy of osteoporosis of various origins.
2. Pregnant and lactating women - to eliminate calcium deficiency.
3. As a basic drug during therapy with antiresorbents and bone formation stimulators.
4. To reduce the risk of bone fractures.

How to take Calcemin

Adults and children over 12 years of age are prescribed one tablet twice a day, taken with meals. If necessary during pregnancy, the medication can be taken after the 20th week and then until the end of the breastfeeding period, one tablet twice a day. The duration of taking the drug for the treatment of osteoporosis in adults is three months. Prevention of osteoporosis requires a course of one month. For calcium deficiency in adults and children – two to three months. The course can be repeated at monthly intervals.

special instructions

When taking the drug, it is necessary to take into account a number of circumstances, which will help maximize the effectiveness of treatment:

1. You cannot exceed the recommended doses, which must be calculated taking into account calcium and vitamin D from food.
2. In the presence of such factors as simultaneous use of calcium channel blockers, cardiac glycosides, it is necessary to monitor the condition of the kidneys through a blood serum test for creatine.
3. In patients with moderate or mild renal failure, it is recommended to periodically measure the level of phosphate, creatine and calcium in the blood and urine (calcium, phosphorus).
4. Use with caution in immobile patients due to the risk of hypercalcemia.
5. The product does not affect concentration, so it can be used when driving.

During pregnancy

During pregnancy and breastfeeding, the medication is used with caution, under the supervision of a doctor. Recommended doses are considered safe, but chronic overdose will result in complications for the fetus or newborn. Hypercalcemia in a pregnant woman leads to pathologies in the child:

• inhibition of parathyroid hormone;
• hypocalcemia;
• tetany;
• epileptic seizures;
• aortic stenosis syndrome;
• retinopathy;
• mental retardation;
• growth disturbance;
• development of hypercalcemia.

Calcemin for children

The drug is not used by children under 12 years of age. This limitation is due to the fact that the use of calcium with vitamin D3 in the given dosages may adversely affect the growth, development of the skeletal system and musculoskeletal system of the child. But during the period of intensive growth of adolescents, the use of tablets will help balance the state of the body.

Drug interactions

• the drug reduces the absorption of glucocorticoids - it is advisable to wait 2-6 hours between doses of these drugs;
• levothyroxine is taken 4 hours before taking calcium, phosphates, bisphosphonates, fluorides - half an hour before, or preferably on another day;
• Thiazide diuretics reduce urinary calcium excretion; serum levels should be checked regularly;
• the drug increases the risk of fatal arrhythmia of cardiac glycosides (Digoxin) and reduces the effectiveness of calcium channel blockers (Verapamil) for atrial fibrillation;
• ion exchange resins (Cholestyramine), laxatives, Orlistat, Carbamazepine, Phenytoin, barbiturates reduce the absorption of vitamin D and the severity of its effect.

Side effects

Those taking the medication rarely report side effects. The main ones are mild nausea, allergic reactions and others:

• gastrointestinal pain, dyspepsia, constipation, flatulence, vomiting;
• anaphylactic reactions, shock, asthma syndrome, rash;
• loss of appetite, granulomatosis, diarrhea, thirst, dizziness;
• urticaria, swelling, redness of the skin, itching, non-cardiogenic pulmonary edema;
• hypercalcemia, hypercalciuria, hypervitaminosis D.

Overdose

Doctors rarely report a drug overdose. More often this is due to the deliberate use of a large number of tablets. To eliminate the signs, it is recommended to rinse the stomach, drink plenty of fluids and follow a diet low in calcium. When taking a dose of 2500 mg of calcium and 4000 IU of vitamin D/day, toxicity and calcification may occur.

Analogues

Among the available analogues of Calcemin, complex biological supplements with calcium are distinguished. There are no other substitutes for the drug, because they cannot provide the proper therapeutic effect. Analogues of the drug are:

• Kalceos – chewable tablets with lemon flavor;
• Calcium-D3-Nycomed is the most popular calcium preparation, suitable for all ages;
• Calcium-D is an oral suspension suitable for infants and adults.

What is the difference between Kalcemin and Kalcemin Advance?

Both drugs are produced by the same manufacturer and have a similar composition, but Calcemin Advance contains magnesium. Another difference is the concentration of calcium and vitamin D3 - in Advance there are 500 mg of calcium and 200 IU of vitamin D3 versus 250 mg and 50 IU. Calcemin Advance is used from the age of 12 (the usual drug is from the age of five), and is prescribed to pregnant women with caution.

Price

The cost of the drug depends on the markup and purchasing conditions of the pharmacy. There is only one manufacturer of the drug - the German company Bayer Pharma. The table shows approximate prices for the drug in pharmacies in Moscow and St. Petersburg.

A drug Calcemin Advance - vitamin and mineral complex, which influences the maintenance of phosphorus-calcium balance in the body.

He reduces the risk of developing osteoporosis and other diseases of the musculoskeletal system, replenishes calcium deficiency in adolescents and strengthens musculoskeletal tissue.

Calcemin Advance is not considered a drug. It belongs to the group of preventive vitamin preparations.

But when using it, it is important to follow the manufacturer’s instructions. It is advisable to consult a doctor before taking it.

Instructions for use

Release form

Calcemin Advance is available in the form of oval tablets coated with a pink film. They are packaged in plastic bottles of 30/60/120 pieces. Each package contains one bottle. Sold through the pharmacy chain. No prescription is needed to purchase.

Compound

The active ingredients of Calcemin Advance are:

• Calcium carbonate (calcium carbonate) is a chemical compound of inorganic origin. Has antiulcer, antacid effect. Completely neutralizes or weakens the effects of hydrochloric acid that cause damage to the walls of the intestines and stomach. Slows down the resorption (absorption) of bone tissue. Reduces the activity of osteoclasts, which dissolve the mineral component of bone tissue. Normalizes electrolyte balance. Helps accelerate the transmission of nerve impulses. Stabilizes cardiac activity. Normalizes blood clotting.
• Calcium citrate- an intermediate compound released during the fermentation of citric acid. Promotes saturation of the body with calcium in case of latent tetany, hypoparathyroidism, rickets, osteoporosis. Has a urine alkalizing effect. Suppresses inflammatory infections in the urinary tract and protects against the formation of kidney stones.

Video: "Taking Calcemin Advance during pregnancy"

Storage conditions

The drug is stored in a dry place, protected from direct sunlight and access by children, observing the temperature regime (not lower than +15°C and not higher than +25°C). Vitamins should be consumed within three years from the date of manufacture. It is indicated in the instructions and on the cardboard packaging.

Price

The cost of Kalcemin Advance in Russian pharmacies depends on the number of tablets and a number of other factors. Minimum price - 235 rubles (for 30 pcs.); maximum - 775 rubles (120 pcs.). In various pharmacies in Ukraine, a bottle with 30 tablets costs from 57 to 80 hryvnia, a pack of 60 tablets may cost from 96 to 105 hryvnia.

Analogues

If you are individually intolerant to Calcemin Advance, your doctor may suggest an analogue of the drug.

Video: "Review of calcium preparations"

Calcium is an important structural component of bone tissue, ensures normal permeability of the vascular wall, interneuronal and neuromuscular conduction, cardiac automatism, takes part in the contraction of striated and smooth muscles, and the process of blood clotting. Calcium carbonate is the salt with the highest elemental calcium content. Calcium citrate reduces the dependence of the bioavailability of the drug on the state of the gastrointestinal tract and the stage of digestion, reduces the risk of stone formation in the urinary tract with long-term use, and also reduces the excessive activity of parathyroid hormone.
Vitamin D contributes to the normal absorption of calcium and its participation in the construction and regeneration of bone tissue.
Zinc is a component of more than 200 enzymes involved in the synthesis of proteins and nucleic acids responsible for gene expression, cell growth and restoration. Ensures normal alkaline phosphatase activity.
Copper takes part in the synthesis of collagen and elastin, preventing bone demineralization.
Manganese normalizes the synthesis of glycosaminoglycans necessary for the formation of bone and cartilage tissue. Duplicates the calcium-sparing functions of vitamin D.
Boron regulates the activity of parathyroid hormone, which in turn regulates the metabolism of calcium, magnesium, phosphorus and colecalciferol. Regardless of vitamin D3, it affects the metabolism of calcium, phosphorus and magnesium.
Calcium absorbed into the gastrointestinal tract and excreted from the body in feces, urine and sweat. Active calcium transport is directly proportional to the presence of calbindin in intestinal cells, the biosynthesis of which depends on the active metabolite of vitamin D - calcitriol.
Vitamin D quickly absorbed in the small intestine. From blood plasma and lymph it penetrates into the liver, bones, muscles, adrenal glands, myocardium, and adipose tissue. It is excreted with bile into the intestines, from where it is partially absorbed. Subsequently it turns into inactive metabolites.
Zinc absorbed in the intestine, excreted in feces (90%) and urine (2-10%).
Copper partially absorbed in the small intestine. The rest is excreted in the feces in the form of insoluble compounds. Of the total amount of absorbed copper, about 80% is excreted in bile, 16% in the walls of the gastrointestinal tract, and 4% in urine. A small amount is excreted in sweat.
Bor quickly absorbed from the gastrointestinal tract and excreted mainly (up to 90%) in the urine.

Indications for use of the drug Kalcemin

For the prevention of osteoporosis and other diseases of the musculoskeletal system, teeth and periodontal disease. To replenish the deficiency of calcium, vitamin D and minerals when they are deficient in the diet, in children during intensive growth, during pregnancy and lactation.

Use of the drug Kalcemin

Adults and children over 12 years old - 1 tablet 2 times a day; children aged 5-12 years - 1 tablet 1 time per day before or during meals. There are no strict restrictions regarding the duration of taking the drug.

Contraindications to the use of the drug Kalcemin

Increased individual sensitivity to any of the components of the drug (allergic reactions).

Side effects of the drug Calcemin

May occur in case of overdose or increased individual sensitivity to the ingredients of the drug. In rare cases - moderate nausea, allergic reactions.

Special instructions for the use of the drug Kalcemin

Children under 5 years of age are prescribed only according to strict indications and under medical supervision.

Interactions of the drug Calcemin

Overdose of the drug Calcemin, symptoms and treatment

Overdose has not been described for the drug Kalcemin. If the dose is exceeded, symptomatic therapy is recommended - gastric lavage, drinking plenty of fluids, and a diet low in calcium.

Storage conditions for the drug Kalcemin

In a dry, dark place at room temperature.

List of pharmacies where you can buy Calcemin:

• Saint Petersburg