Regulon interaction with other drugs. Regulon - instructions for use, analogs, reviews and release forms (contraceptive pills) of a drug for contraception in women, including during pregnancy. Side effects (discharge,

Photo of the drug

Latin name: Regulon

ATX code: G03AA09

Active substance: Ethinylestradiol + Desogestrel

Manufacturer: JSC Gedeon Richter, Hungary

Description is valid on: 14.11.17

Regulon is a monophasic contraceptive drug intended for internal use. Used to protect against unwanted pregnancy and eliminate menstrual irregularities.

Active substance

Ethinylestradiol + Desogestrel.

Release form and composition

The drug is available in tablets of 21 and 63 pieces per package.

Indications for use

Prescribed for contraception and for the treatment of a number of menstrual disorders: premenstrual syndrome, painful periods and dysfunctional uterine bleeding.

Contraindications

Contraindications to taking the drug:

• venous and arterial thrombosis;
• severe liver disease, hepatitis or cholestatic jaundice;
• angina pectoris, transient ischemic attack;
• history of venous thromboembolism;
• Gilbert's syndrome, Rotor's syndrome or Dubin-Johnson syndrome;
• migraine with the presence of focal neurological symptoms;
• factors indicating a possible risk of venous or arterial thrombosis;
• hormone-dependent malignant tumors of the genital organs and mammary glands;
• vaginal bleeding of unknown etiology;
• cholelithiasis;
• diabetes;
• liver tumors;
• jaundice when taking GCS;
• dyslipidemia;
• pancreatitis;
• otosclerosis, severe itching;
• hypersensitivity to the components of the drug;
• smoking in patients over 35 years of age;
• pregnancy and lactation period.

Prescribe with caution to patients in the following cases:

• arterial hypertension;
• migraine;
• there is a risk of venous or arterial thrombosis;
• valvular heart disease;
• with atrial fibrillation;
• in the presence of varicose veins and superficial thrombophlebitis;
• for acute or chronic liver diseases;
• in the presence of valvular heart defects;
• with Crohn's disease;
• for epilepsy;
• with sickle cell anemia;
• with the development of ulcerative colitis;
• with hypertriglyceridemia;
• after major surgical interventions;
• after surgery of the lower extremities;
• for severe injuries;
• for obesity;
• with severe depression;
• in the postpartum period;
• women who smoke;
• women over 35 years of age.

Instructions for use Regulon (method and dosage)

The drug is taken orally from the 1st day of the menstrual cycle. Take 1 tablet per day for 21 days at the same time. After taking the last tablet, there is a break of 7 days, during which menstruation should begin. A week later, the drug is resumed according to the usual regimen (even if menstrual flow continues). Reception continues as long as there is a need for contraception.

• If taking the drug begins on days 2-5 of the cycle, it is recommended to use additional contraception in the first 7 days. If more than 5 days have passed since the start of menstruation, the start of therapy should be postponed until the 1st day of the next MC.
• After childbirth, you can take the drug on the 21st day (in the absence of lactation) after prior consultation with your doctor. There is no need to use additional contraception.
• If you start taking the drug later than 21 days after birth, it is recommended to use additional contraception for 7 days.
• After an abortion, you should start taking Regulon the next day after the operation. In this case, there is no need to use other methods of contraception.
• When switching to Regulon from another oral contraceptive, you should start taking it the next day after finishing the previous pack. After 21 days, you should take a break of 7 days.
• When switching from a mini-pill, you should start taking Regulon on the first day of the menstrual cycle.
• If it is necessary to delay menstruation, you must continue taking the pills without a 7-day break. During this period, menstrual-like bleeding may appear. The usual use of the drug can be resumed after a break of 7 days.
• If you miss a pill for less than 12 hours, you can simply take the missed pill and continue the course as usual. If more than 12 hours have passed, the use of additional barrier contraceptives is recommended.
• If a missed pill occurs in the 1st or 2nd week of MC, you should take 2 pills at once (as usual) and use additional barrier contraceptives until the end of the cycle.
• If you miss a dose in the 3rd week, you must take a pill and continue the course without a 7-day break.

Side effects

May cause the following side effects:

• From the cardiovascular system: arterial or venous thromboembolism, arterial hypertension.
• From the senses: partial hearing loss associated with otosclerosis.
• Other: Sydenham's chorea, hemolytic-uremic syndrome, porphyria.

Less common side effects:

• From the digestive system: nausea, ulcerative colitis, vomiting, Crohn's disease, cholestasis, the occurrence or exacerbation of jaundice.
• From the central nervous system: headaches, frequent mood swings, depression.
• From the reproductive system: inflammatory processes of the vagina, enlargement of the mammary glands or painful sensations in them, acyclic bleeding from the vagina, galactorrhea, candidiasis.
• From the metabolic side: fluid stagnation in the body, weight gain or decreased tolerance to carbohydrates.
• From the organs of vision: sensitivity of the cornea when wearing contact lenses.
• Dermatological reactions: rash, nodular or exudative erythema.
• Other: allergic reactions.

Overdose

In case of an overdose, nausea and vomiting occur.

To eliminate symptoms, gastric lavage should be performed. Additionally, symptomatic therapy is used.

Analogs

Analogs by ATX code: Benidetta, Daisy-30, Marvilon, Mercilon, Novinet.

Do not decide to change the drug on your own; consult your doctor.

pharmachologic effect

The main effect of Regulon is associated with the suppression of ovulation and inhibition of the synthesis of gonadotropins. By inhibiting the ovulation process, the drug makes it difficult for sperm to penetrate the uterus, and also prevents the fertilized egg from reaching the uterine wall.

The active substances of Regulon are the female sex hormones desogestrel and ethinyl estradiol. Ethinyl estradiol is a synthetic analogue of endogenous estradiol. As for desogestrel, it has a pronounced antiestrogenic and gestagenic effect, and exhibits minor androgenic and anabolic activity.

When used, there is a significant reduction in blood loss during menstruation, the menstrual cycle is normalized and the general condition of the skin improves.

special instructions

Before prescribing the drug, a complete medical examination of the patient is carried out to confirm the absence of contraindications and pregnancy. While taking Regulon, the woman's physical condition should be periodically monitored.

Does not protect against sexually transmitted diseases.

The drug does not affect the ability to drive vehicles or operate complex machinery.

During pregnancy and breastfeeding

Contraindicated during pregnancy and breastfeeding.

In childhood

The drug is not used in children.

In old age

It is prescribed with special caution to women over 35 years of age and is not used after menopause.

For impaired renal function

Use with extreme caution in the presence of renal failure.

For liver dysfunction

The drug is contraindicated in liver failure.

Drug interactions

The effectiveness of Regulon is reduced by: Rifampicin, Hydantoin, Felbamate, Primidon, Carbamazepine, Griseofulvin, Oxcarbazepine, Topiramate, barbiturates and preparations based on St. John's wort.

The drug is also less effective in combination with Ampicillin and Tetracycline. If it is necessary to use it together with these antibiotics, it is recommended to resort to additional barrier methods of contraception throughout the course, as well as for a week after discontinuation of the drug.

Conditions for dispensing from pharmacies

3.81 out of 5 (13 Votes)

Prices in online pharmacies:

Regulon is a monophasic contraceptive.

Release form and composition

The dosage form of the drug is film-coated tablets (21 pieces in a blister, 1 or 3 blisters in a cardboard box).

The active ingredients in Regulon birth control pills include:

• Ethinyl estradiol (30 mcg/tablet);
• Desogestrel (150 mcg/tablet).

Auxiliary components are:

• Magnesium stearate;
• Stearic acid;
• Alpha tocopherol;
• Povidone;
• Colloidal silicon dioxide;
• Potato starch;
• Lactose monohydrate.

Shell composition:

• Propylene glycol:
• Hypromellose;
• Macrogol 6000.

Indications for use

Regulon is used to prevent unwanted pregnancy.

Contraindications

Taking pills is contraindicated:

• Women who have suffered thrombosis/thromboembolism of veins or arteries;
• In the presence of multiple or pronounced risk factors for thrombosis of veins or arteries;
• If there is a history of indications of precursors of thrombosis, including angina pectoris and transient ischemic attacks;
• For migraines that are accompanied by focal neurological symptoms (including a history);
• Patients with diabetes mellitus complicated by angiopathy;
• For pancreatitis accompanied by severe hypertriglyceridemia (including if the disease is noted in the anamnesis);
• For dyslipidemia;
• In case of severe liver diseases, hepatitis, cholestatic jaundice, including those that developed during a previous pregnancy (it is allowed to start taking Regulon no earlier than three months after normalization of laboratory and functional liver parameters);
• For jaundice caused by the use of glucocorticosteroids;
• With cholelithiasis (including a history);
• With familial benign hyperbilirubinemia (with Rotor, Gilbert or Dabin-Johnson syndromes);
• With tumor diseases of the liver (including a history);
• In cases where, during a previous pregnancy or while taking glucocorticosteroids, a woman developed or worsened otosclerosis, or experienced severe itching;
• If the patient has malignant hormone-dependent tumors of the mammary glands or genital organs, as well as if the presence of neoplasms is suspected;
• For vaginal bleeding of unknown origin;
• If you are pregnant or suspected of it;
• During breastfeeding;
• Women over 35 years of age who smoke more than 15 cigarettes per day;
• In case of hypersensitivity to the components of the drug.

Relative contraindications to the use of Regulon are conditions that increase the risk of developing thrombosis or thromboembolism of veins/arteries. These include:

• Smoking;
• Epilepsy;
• Family history;
• Age over 35 years;
• Severe injury;
• Obesity;
• Migraine;
• Dyslipoproteinemia;
• Arterial hypertension;
• Extensive surgery;
• Varicose veins or superficial thrombophlebitis;
• Surgery on the lower extremities;
• Changes in biochemical parameters;
• Severe depression (including a history);
• Postpartum period;
• Diabetes mellitus without vascular complications;
• Morphological changes in the heart valve;
• Systemic lupus erythematosus (SLE);
• Prolonged immobilization;
• Ulcerative colitis;
• Atrial fibrillation;
• Crohn's disease;
• Sickle cell anemia.

Directions for use and dosage

Regulon tablets are taken orally.

It is optimal that the first dose occurs on the first day of the menstrual cycle. For 3 weeks, a woman should take 1 tablet daily (at the same time if possible). From 22 to 28 days of the cycle there is a break. Withdrawal bleeding usually occurs at this time. Exactly 4 weeks after the first dose of the drug, on the same day of the week, the course is resumed - they begin taking tablets from a new blister, regardless of whether the withdrawal bleeding has ended or not.

This regimen is followed as long as the need for contraception continues. If a woman does not miss a dose and follows all recommendations, the contraceptive effect continues during the seven-day break.

If a woman starts taking Regulon from the 1st day of the cycle, additional contraception is not needed. If taking pills is started between days 2 and 5 of the cycle, barrier contraceptives must be used during the first week. If more than 5 days have passed since the start of menstruation, it is recommended to take the drug in the next cycle.

After childbirth, if a woman is not breastfeeding, taking pills is allowed to begin after 3 weeks, but only after consultation with the attending physician. In this case, there is no need to use additional methods of contraception. If there was sexual intercourse after childbirth, taking the pills should be postponed until the first menstruation.

When the decision to take COCs (combined oral contraceptives) is made later than 3 weeks after birth, barrier contraceptives should be used during the first week of using Regulon.

After an abortion, in the absence of contraindications, pills should be taken from 1 day after surgery. Additional contraception is not needed in this case.

When switching to Regulon from another contraceptive for oral use, it is recommended to take the first tablet the day after the last tablet from the pack for a 28-day course is taken, or the day after the end of the week-long break if using the drug, which is designed for a 21-day course. There is no need to use additional contraception.

If a woman switches to Regulon from a mini-pill, the first tablet should be taken on the 1st day of the cycle. Additional contraception is not needed in this case.

If a woman does not have menstruation while taking the mini-pill, then Regulon can be taken any day, but only after pregnancy has been ruled out. During the first week of using the drug, you should use barrier contraceptives or abstain from sexual relations. The use of the calendar method in this case is recommended.

When it is necessary to delay menstrual bleeding, after completing the 21-day course, you should continue taking tablets from the new blister without the usual seven-day break. During this period, spotting or breakthrough bleeding may appear from the genital tract, which does not interfere with the contraceptive effect of the drug. Regular use of the drug is restored after the usual seven-day break.

If a woman has forgotten that she needs to take a pill, and less than 12 hours have passed since the missed pill, she just needs to take the missed pill and continue the course, taking the drug according to the usual regimen.

If more than 12 hours have passed, the reliability of contraception decreases, therefore:

• If you miss a dose in the first or second week of the cycle, you need to take 2 tablets at once the next day, and then continue using Regulon according to the usual regimen, using additional contraception until the end of the cycle;
• If a pill was missed in the third week, it should be taken as early as possible and continue using the drug without maintaining the standard seven-day interval between courses, using additional methods of contraception.

The absorption of Regulon may be impaired if a woman experiences vomiting or diarrhea after taking the pill. When symptoms stop within 12 hours, it is recommended to take an additional tablet and continue using the drug as usual. If symptoms persist for more than 12 hours, barrier contraception should be used throughout the period of vomiting/diarrhea and for the next 7 days.

Side effects

The most severe but rare side effects that are possible during the use of Regulon are:

• Arterial hypertension;
• Thromboembolism of veins/arteries;
• Hearing loss (as a complication of otosclerosis);
• Porphyria;
• Hemolytic-uremic syndrome;
• Exacerbation of reactive SLE;
• Sydenham's chorea (is transient and disappears after discontinuation of COCs).

If any of the above phenomena occur, you should immediately stop taking the drug.

Relatively common adverse reactions of Regulon are:

• Acyclic spotting or bleeding from the genital tract;
• Amenorrhea after stopping the drug;
• Inflammatory processes in the genital tract;
• Changes in the state of vaginal secretions;
• Thrush;
• Galactorrhea;
• Increased size, tension and soreness of the mammary glands;
• Nausea;
• Crohn's disease;
• Vomit;
• Ulcerative colitis;
• Headache;
• Cholelithiasis;
• Erythema (nodular or exudative);
• Chloasma;
• Rash;
• Development/exacerbation of itching and/or jaundice associated with cholestasis;
• Migraine attacks;
• Mood lability;
• Depression;
• Increased sensitivity of the cornea (which can cause intolerance to contact lenses);
• Fluid retention in the body;
• Decreased tolerance to carbohydrates;
• Weight change (usually upward);
• Hypersensitivity reactions.

In all the described cases, the decision on the advisability of further taking Regulon is made by the doctor on an individual basis after assessing the benefit/risk ratio.

An overdose of Regulon may result in nausea and vomiting, and bleeding from the genital tract. In the first 2-3 hours after taking a high dose of the drug, it is recommended to perform gastric lavage. The drug does not have a specific antidote; further treatment is symptomatic.

special instructions

A decrease in the effectiveness of COCs, including Regulon, is observed when they are used simultaneously with drugs that are characterized by the ability to induce liver enzymes. These include:

• Primidone;
• Hydantoin;
• Rifampicin;
• Barbiturates;
• Carbamazepine;
• Topiramate;
• Oxcarbazepine;
• Felbamate;
• St. John's wort preparations;
• Griseofulvin.

In addition, women taking Regulon simultaneously with the medications listed above significantly increase the risk of developing breakthrough bleeding. The maximum level of induction is usually achieved after 2-3 weeks of use, but may persist for up to 4 weeks after discontinuation of the drug.

The effectiveness of Regulon is also reduced if taken during treatment with drugs of the ampicillin and tetracycline group. If it is necessary to use them together, it is recommended to use additional contraception throughout the course and for another 7 days after discontinuation of antibiotics; for rifampicin, this period increases to 28 days.

COCs can reduce carbohydrate tolerance and may increase the need for oral antidiabetic drugs and insulin.

Analogs

Novinet, Mercilon, Marvelon.

Terms and conditions of storage

The tablets should be stored in a dry place at a temperature of 15° to 30°C.

The shelf life of Regulon is 3 years.

The modern market of contraceptives with hormonal components is represented by a wide variety of products. These include tablet formulations, vaginal rings, and even patches and injections. Thanks to such a variety of medicinal compositions, every woman can choose the contraception option that will be optimal for her. Gynecological specialists say that it is best for young and nulliparous girls to turn their attention to monophasic formulations. One of these contraceptive medications is Regulon.

What is the composition of Regulon?

This composition is sold in tablet form, each unit has a round, biconvex shape and is white in color. Each tablet contains one hundred and fifty micrograms of desogestrel, as well as thirty micrograms of ethinyl estradiol.

The first of these components has a persistent antiestrogenic and progestogenic effect, and additionally has mild anabolic and androgenic activity. Ethinyl estradiol is a synthetic analogue of the hormone estradiol.

Auxiliary components include substances such as lactose monohydrate, alpha-tocopherol and potato starch. Additional ingredients also include colloidal silicon dioxide, povidone, magnesium stearate and stearic acid. Each blister contains twenty-one tablets.

What does Regulon do?

Consumption of this drug leads to suppression of ovulatory processes and also stimulates inhibition of the production of gonadotropins. Regulon leads to an increase in the viscosity of cervical mucus, which significantly complicates and slows down the passage of sperm through the cervical canal. In addition, some deviations of the endometrium occur in the uterus, due to which the fertilized egg simply cannot implant.

The use of Regulon has a positive effect on lipid metabolism, increasing the concentration of HDL within the blood plasma and without having any effect on LDL.

When using this medicinal composition, there is a noticeable reduction in the loss of menstrual blood, while the menstrual cycle is somewhat shortened, and the condition of the epidermis is optimized.

What is the use of Regulon?

The instructions for use recommend using Regulon only after consulting a doctor and passing a series of tests. The tablet composition of Regulon is intended for oral consumption. They begin to be consumed starting from the very first day of the menstrual cycle (on the first day of the onset of menstruation), continuing consumption for twenty-one days. To achieve maximum effectiveness, it is worth taking it at the same time of day (plus or minus half an hour). After consuming the last tablet, it is recommended to take a break for one week. It is at this time that menstruation should occur.

The consumption of the next blister begins after the week break has expired. Accordingly, this will be the first day of the fifth week after taking the very first tablet of the medicine. With proper consumption of Regulon, its contraceptive effect is maintained for a period of a week-long break.

If you forget to take one tablet, you should take it within twelve hours. In this case, no additional contraception is required.

If consumption is missed for a period of more than twelve hours, the efficiency of Regulon consumption decreases by an order of magnitude. Accordingly, there is a need to find and use additional means of contraception, for example, a condom.

What are the side effects of Regulon?

According to the instructions, Regulon can provoke the development of a number of side effects. Thus, the appearance of certain pathological conditions requires discontinuation of the use of the drug, this applies to hearing loss due to otosclerosis, the development of venous or arterial thromboembolism and hypertension. It is also worth stopping the use of this medication if the patient develops porphyria, Sydenham chorea, exacerbations of reactive systemic lupus erythematosus and hemolytic-uremic syndrome.

Regulon can also provoke other symptoms, which are much more common, but if they appear, there is no need to urgently stop using the medicine. So, in certain situations, this contraceptive can cause acyclic bleeding from the vaginal cavity and changes in the state of vaginal mucus. The patient may notice pain and tension in the mammary glands, and the breasts may also increase in size. Sometimes candidiasis, galactorrhea occur, inflammatory lesions of the vagina are formed, as well as amenorrhea after stopping the drug.

Consumption of the drug is sometimes accompanied by migraines, headaches, depression and mood swings. A small proportion of patients develop Crohn's disease, nausea or vomiting, ulcerative colitis, or jaundice develops or worsens due to cholelithiasis or cholestasis.

If the patient wears contact lenses, she may experience increased sensitivity of the cornea. Side effects also include the appearance of dermatological problems - erythema nodosum and exudative erythema, chloasma. Some girls experience increased body weight, increased swelling, and decreased tolerance to carbohydrates. Various allergic reactions may also occur.

Name: Regulon

Pharmacological effects:
A combined contraceptive that includes an estrogen component (ethinyl estradiol) and a gestagen (desogestrel). The mechanism of action is associated with inhibition of the production of gonadotropins (FSH and luteinizing hormones) by the pituitary gland, which complicates ovulation and increases the density of cervical mucus, which prevents the penetration of sperm into the uterine cavity.

Regulon - indications for use:

- contraception;
- treatment of menstrual disorders such as dysmenorrhea, PMS, dysfunctional uterine bleeding.

Regulon - method of application:

You should start taking Regulon from the first day of the menstrual cycle, without using additional methods of contraception. If the first dose of Regulon occurs on days 2-5 of the menstrual cycle, contraception by other methods is recommended for at least a week. If more than 5 days have passed since the beginning of the cycle, Regulon should be taken from the next cycle.

The drug is taken 1 tablet 1 time per day, preferably at the same time, after taking 21 tablets, a break is needed for a week, during which a menstrual-like reaction occurs. After a week, they begin taking a new package of Regulon, even if the bleeding has not stopped yet.
After childbirth, taking the medicine is possible only when the woman is not breastfeeding. Start taking the medication on the 21st day of the postpartum period. If you have already had sexual intercourse since giving birth, you should postpone taking the medicine until your menstruation. When taking the first Regulon tablet after 21 days of the postpartum period, additional contraception is required for 7 days.

When switching from another oral contraceptive, it is suggested to start taking Regulon the next day after finishing taking all the tablets from the package of the previous contraceptive.
If it is necessary to delay the onset of the next menstruation, you should start taking the tablets from the next package, without a week's break.

Regulon - side effects:

From the gastrointestinal tract: nausea, vomiting, extremely rarely - liver dysfunction.
From the reproductive organs and reproductive system: intermenstrual bleeding, amenorrhea, disturbances in the composition of the correct vaginal microflora, changes in vaginal secretion, decreased libido, discomfort in the mammary glands. Very rare growth of uterine fibroids.
From the circulatory system: increased blood pressure, very rarely thrombosis and thromboembolism of various locations.
From the central nervous system: frequent mood swings, depression, headache, often of a migraine-like nature.
From the endocrine system: weight gain.
Others: rash, erythema nodosum, discomfort when wearing contact lenses, development of reactive SLE.

Regulon - contraindications:

- intolerance to any of the components of the drug;
- pregnancy or breastfeeding;
- severe liver disease, functional hyperbilirubinemia (Rotor and Dubin-Johnson syndrome), a history of jaundice in pregnancy;
- familial forms of hyperlipidemia;
- arterial hypertension of severe or moderate severity;
- history of thrombosis or thromboembolism;
- migraine;
- SCR;
- herpes type 2;
- bleeding from the genital tract of unknown etiology;
- presence of estrogen-dependent tumors or suspicion of them;
- epilepsy;
- severe forms of diabetes mellitus, as well as diabetes in pregnant women;
- presence of coagulation system disorders.

Regulon - pregnancy:

Pregnancy is an absolute contraindication to prescribing the medication.

Interaction with other drugs:
Do not use simultaneously with antibiotics (especially ampicillin, rifampicin, tetracycline), as it is likely to disrupt the cycle and reduce the contraceptive effect. If these antibiotics are necessary, additional methods of contraception may be necessary. A decrease in the effect of contraception and disruption of the cycle is also likely when taking barbiturates, some antispasmodics, antidepressants, and laxatives.
When combined with anticoagulants, additional monitoring of prothrombin time and adjustment of the dosage of the anticoagulant is required.
Do not combine with hepatotoxic drugs due to an increased risk of complications.

Regulon - overdose:

Symptoms of overdose: severe headache, dyspepsia, cramps in the calf muscles. Therapy is only symptomatic, since there is no specific antidote.

Regulon - release form:

Film-coated tablets, 21 or 63 tablets per pack.

Regulon - storage conditions:

Store at a temperature not exceeding 30 degrees Celsius.

Regulon - composition:

Ethinyl estradiol - 0.03 mg.
Desogestre - 0.15 mg.

Excipients: magnesium stearate, alpha-tocopherol, colloidal anhydrous silicon, povidone, potato starch, lactose monohydrate, propylene glycol, macrogol, hypromellose, stearic acid.

Regulon - additionally:

Regulon is prescribed after a thorough examination and history taking in order to exclude the presence of diseases, the course of which may worsen while taking the medication.
If liver tests (transaminase levels, bilirubin levels) worsen, the medication should be stopped immediately.
In the first months of taking the medicine, intermenstrual bleeding may occur, but these symptoms do not require discontinuation of the medicine. If they last more than three months, a more detailed study is needed.

The risk of thromboembolic complications increases with smoking, so women taking Regulon are advised to completely give up cigarettes.
With vomiting or diarrhea, the contraceptive effect of the drug may be reduced, so it is better to use additional methods of contraception.
If pregnancy is planned, Regulon should be stopped at least 3 months in advance.

If no menstrual-like reaction is noticed from the second month of taking the medicine, pregnancy must be excluded.
Regulon is not prescribed when breastfeeding, as the drug can lead to a decrease in lactation.
If a pill is missed, you should take the missed pill and continue taking the medication as prescribed. If the missed pill is taken within 36 hours of the previous one, additional contraceptive measures are not required.
The teratogenic effect of the drug has not been proven, so pregnancy that occurs while taking Regulon does not require termination.

Important!
You should consult your doctor before using the medicine. This instruction is intended for informational purposes only.

Side effects of contraceptives can be serious and require immediate discontinuation of the drug. There is also a moderate group, that is, a woman can continue to take pills for some time.

Review of Regulon - many side effects (mandarinka92, irecommend.ru)

Let's look at the side effects medium and light weight:

• Often, when starting to use Regulon, a woman may experience bloody issues, which have nothing to do with the menstrual cycle.
• If you suddenly stop taking pills after taking them for a long time, you may experience endometrial rejection, which leads to the absence of menstrual bleeding, as a result of which a woman cannot become pregnant.
• It may happen while taking pills changes in the normal microflora of the vagina. In this case, thrush or bacterial vulvovaginitis often occurs.
• Tablets often cause stomach upset. In this case, the woman may experience nausea accompanied by vomiting. This side effect is also characterized by stool upset.
• Frequent mood swings, prolonged depression- also refers to a side effect of the contraceptive.
• The most common symptom of an adverse reaction in the body is painful sensations, which can be localized in the lower abdomen or in the form of headaches.
• Very often, patients complain that when taking Regulon they become gain weight quickly. Fullness is another side effect. In fact, the hormones themselves that are contained in the tablets do not affect weight gain, but can significantly increase a woman’s appetite, as a result of which the patient gains weight.
• Like any other drug, Regulon can provoke allergic reaction in the form of skin itching and rash.
• Possible swelling that occurs in the morning.

The above symptoms are of moderate severity, that is, they do not require immediate discontinuation of the drug.

In case of side effects, you should definitely consult a gynecologist. Only a doctor can select individual birth control pills.

Regulon: severe side effects

Review of the side properties of Regulon (Ladl3ndiya, irecommend.ru)

We list some pathologies and symptoms that require urgent drug withdrawal:

• Serious side effects include diseases associated with the cardiovascular system. It is worth noting that serious side effects are very rare, occurring in approximately 0.01 cases. Otherwise, the drug would not be on sale in pharmacy chains.
• Blood clots in the lower extremities, hepatic thromboembolism, and heart attack or stroke may develop.
• It is possible to develop atherosclerosis, which causes complications in the form of deterioration of vision and hearing.
• If a woman starts taking pills during pregnancy, this can cause a miscarriage or affect the development of the fetus in the womb.

In what cases is taking pills prohibited?

Let's consider some factors in which taking the drug Regulon is strictly contraindicated:

• If a woman is carrying a child or a pregnancy test shows two lines.
• Serious liver pathologies.
• Malignant formations.
• If the patient notices spotting independent of the menstrual cycle.
• Breastfeeding a baby.
• Vein diseases, including thromboembolism of various etiologies.
• Regular high blood pressure. In this case we are talking about an indicator higher than 160\100.

Doctors' opinions and women's reviews

(can be enlarged)

Despite some side effects that occasionally occur in women, doctors speak positively about this drug. Regulon is highly effective in terms of contraceptive action; in addition, it perfectly resolves cysts and is used in the treatment of other pathologies.