The Russian analogue of Nise in tablets is not expensive. An inexpensive analogue of Nise gel in tablets. Contraindications for use

Cheap and effective analogues of Nise gel (ointment) are available in a wide range on pharmacy shelves, but how to choose a truly effective product? is a question that interests many people. When looking for a drug with a pronounced anti-inflammatory, analgesic effect for the treatment of diseases of the musculoskeletal system, you need to carefully study the instructions for use, pay attention to the composition, indications, contraindications, as well as dosages and frequency of use. Having the necessary information about the drug, making a choice is much easier.

Among the large list of medications for topical use, doctors often prescribe Nise ointment or gel for the treatment of joint diseases. The drug has a rapid effect; in complex therapy, it allows the patient to improve the condition of the patient, the mobility of diseased joints, and reduce the risk of complications.

Gel (ointment) Nise is a medicinal product for external use with a pronounced analgesic and anti-inflammatory effect, which is widely used in the treatment of diseases of the musculoskeletal system. The use of ointment in complex treatment will help reduce the symptoms of diseases such as arthritis, arthrosis, gonoarthrosis, osteochondrosis and other pathologies in which there is damage and inflammation of the joints and periarticular tissues. The active component of the drug is nimesulide, which belongs to the non-steroidal anti-inflammatory drugs from the sulfonanilide class.

The mechanism of action of the drug is to suppress the enzyme type 2 cyclooxygenase, which is involved in the synthesis of inflammatory mediators - prostaglandins. The use of Nise ointment or gel, as well as some of its analogs, allows you to inhibit prostaglandins, thereby relieving pain and eliminating inflammation.

Nise is produced for external use in tubes of 20 or 50 grams. You can buy the drug at any pharmacy in the city without a doctor's prescription. The cost of the ointment (gel) is about 250 rubles per package.

Prices for analogues of Nise gel are quite different and directly depend on the manufacturer, the composition of the drug, the supplier and the pharmacy chain itself.

The drug Nise gel, as well as its structural analogues with the same therapeutic effect, are widely used in the complex treatment of the following diseases:

1. Arthritis of joints of different localization and etiology;
2. Osteoarthritis;
3. Osteochondrosis of the cervical, thoracic or lumbar region;
4. Bursitis;
5. Ankylosing spondylitis;
6. Post-traumatic pain;
7. Muscle pain;
8. Various infectious diseases of small and large joints;
9. Neuralgia;
10. Myalgia.

Using Nise gel, like many of its analogues, can also be used for other inflammatory and degenerative diseases of the musculoskeletal system, but before using any product you need consult a doctor.

Treatment of diseases affecting joints and periarticular tissues should always be carried out comprehensively and only after consultation with the attending physician.

List of analogues

Nise ointment (gel), like any other drug, has several analogues, which are divided into structural drugs that have an identical composition or drugs with a different composition but the same therapeutic effect. The list of such drugs is quite extensive, but in practice the following drugs are most often used:

• Sulaydin gel– a product for external use from the group of non-steroidal anti-inflammatory drugs. The active component of the drug is nimesulide 10 mg, which allows Sulaydin gel to be classified as a structural analogue of Nise ointment. The drug has the same mechanism of action and is widely used to treat joint diseases. The cost of Sulaydin gel is about 560 rubles per 30 ml.
• Nimulid gel– a drug with a pronounced analgesic and anti-inflammatory effect based on nimesulide. Used in the treatment of joint diseases in which there is an inflammatory process. The price of the drug ranges from 140 to 250 rubles per 30g package.
• Diclofenac ointment– a common drug from the group of non-steroidal anti-inflammatory drugs, which contains the active component – ​​diclofenac. The medicine has an analgesic and anti-inflammatory effect and can be used in combination with other drugs. The cost of the gel is about 25 rubles per package of 30 grams.
• Ketonal gel– a drug based on ketoprofen, which has analgesic, anti-edematous and anti-inflammatory properties. The drug has a wide range of uses and is also quite well tolerated. The cost of the gel is about 320 rubles per 50 grams.
• Voltaren gel– a topical agent, the use of which allows you to eliminate pain, swelling and inflammation in the joints. The active component of the gel is diclofenac diethylamine. It is produced by a Swiss pharmaceutical company, which explains its high cost, which is about 450 rubles.
• Fastum gel– a drug based on ketoprofen with a powerful analgesic and anti-inflammatory effect. Widely used in the treatment of diseases of the joints and spine. The price of the medicine is from 270 rubles per 30 grams.

It is important to understand that any analogue of Nise ointment (gel) has its own contraindications, adverse reactions and features of use, therefore, before using any medicine, you need to study the instructions and consult with your doctor.

The drug Nise Gel has established itself as an effective medicine that eliminates pain. In addition to the gel, tablets and oral suspension can be found in pharmacies under this brand name. The drug is prescribed for children and adults as a non-steroidal anti-inflammatory drug.

The basis for the use of Nise gel is the treatment of symptoms of inflammatory diseases of the musculoskeletal system: articular syndrome, arthritis, osteoarthritis, osteochondrosis, radiculitis, lumbago, rheumatism, etc.

Medicines are available for children from 2 years of age (in the form of a suspension). The active ingredient in nise is nimesulide. This component is able to penetrate the placental barrier and into breast milk, so it is prohibited during pregnancy and lactation.

The medicine is manufactured in India. In Russia, its prices vary between 175–470 rubles. A review of medications with nimesulide showed that among medications both Russian and imported, you can find cheap analogues of nise gel.

Let's consider close substitutes for Nise gel among drugs from domestic manufacturers. The table offers a comparison of prices and descriptions of similar medications.

Cheap analogues of the drug Nise Gel produced in Ukraine have a different active ingredient, but similar indications for use. A list of modern medicines is presented below.

• Nobi gel. The product will solve the problem of how to replace the Nice gel. Effectively relieves pain, eliminates swelling and swelling. Indications for use: pain after injuries or bruises, tenosynovitis. The average price is 120–145 rubles.
• Fort gel. An inexpensive analogue of Nice gel with the active ingredient – ​​ketoprofen. It is used topically to eliminate post-traumatic pain, sprains, and bruises. Sold as a gel in tubes of 30 and 50 g. The average price is 55–70 rubles.

Belarusian generics are an excellent option for replacing a cheap drug with nimesulide.

Modern imported synonyms will help you choose an inexpensive analogue of Nise in tablets and other dosage forms.

• Aponil. The drug is produced in tablets. It is used to treat pain, reduce temperature, and for inflammatory processes of the musculoskeletal system. Country of origin: Cyprus. The average price is 110–130 rubles.
• Nimesil. The best imported analogue of Nise with a similar effect. The basis of the medicine is nimesulide. Release form: powder for preparing a drink, which is consumed orally. The drug is produced in Italy and Germany. The average price is 25–690 rubles.
• Nimulid. Non-steroidal anti-inflammatory drug with antipyretic and analgesic function. Available in the form of tablets, gel, suspension. Country of origin: India. The average price is 130–355 rubles.
• Nimika. Instant tablets. Indications for use: osteoarthritis, diseases of rheumatic origin, postoperative pain. Fever, dysmenorrhea. The drug is produced in India. The average price is 120–250 rubles.

The anti-inflammatory, analgesic and antipyretic properties of nimesulides make them popular in the group of non-steroidal drugs. They perform an antioxidant function and perfectly relieve pain in a short time. All this, as well as the reasonable cost, forces patients to purchase such drugs without medical advice.

This approach to choosing an anesthetic drug is unacceptable due to the presence of a wide range of contraindications. Children and patients with heart failure, kidney disease, diabetes mellitus and arterial hypertension need to be monitored by a doctor for a possible reaction to the drug.

Pain and inflammation cause a lot of unpleasant sensations, and when intense, they cause agony. In order to eliminate symptoms and treat inflammatory processes, drugs of the synthetic group are used, which include Nise, as well as its analogues.

About the drug

A drug that has an analgesic and anti-inflammatory effect in many pathological processes.

The effect of using a medicine is based on the body's reaction to its composition. The active substance is nimesulide.

Available in the form of regular and dispersible tablets, also in the form of medicinal powder for the preparation of suspension and gel for external use.

Regardless of the form of release, indications for use are pain and inflammation in diseases:

• arthritis of psoriatic or rheumatoid type;
• sciatica or radiculitis;
• joint disorders due to rheumatism or gout;
• spondyloarthritis or osteochondrosis;
• lumbago or arthritis;
• myalgia or arthralgia;
• feverish condition;
• inflammation of soft tissues after injuries;
• bursitis or tendon damage;

Nise tablets and suspension are used to relieve pain, dental pain, menstrual pain and headaches. Nise gel is recommended for traumatic injuries and after operations performed on muscles, bones or joints.

The instructions for use of the drug warn about the undesirable use of the drug in tablets and suspensions for pathologies:

• erosions or ulcers on the mucous membranes of the gastrointestinal tract;
• liver/kidney dysfunction;
• aspirin triad.

Gel Nise is not prescribed if the skin is affected by infection or dermatoses.

Absolute contraindications for any form of release of the analogue are considered to be the period of pregnancy/lactation and sensitivity to the existing composition.

The drug has many side effects, but they most often occur with an overdose or the presence of contraindications. In case of an adverse reaction, the patient experiences symptoms:

• disorders of the stomach and intestines;
• migraine;
• allergies (including anaphylactic shock);
• circulatory disorders.

The average price for Nise gel and tablets is 200 rubles, suspension powder is 300 rubles.

If necessary (due to the high price, contraindications, side effects, etc.), Nise can be replaced with analogues. Depending on the indications, as well as the reason for searching for a substitute, the doctor may prescribe analogs that are cheaper or more expensive than the original. It should be borne in mind that some analogues of this group are sold in pharmacy chains only with a prescription.

Analogues of Nise:

• Nimesulide;
• Ibuprofen;
• Nimulid;
• Nimesil;
• Aertal;
• Aceclofenac.

Nimesulide and Ibuprofen are substitutes that cost much less than the original.

Direct analogue of Nise gel and tablets. The medicine is used for therapy for inflammatory diseases of the musculoskeletal system and other body systems. Also, tablets and gel for external application are used as a strong pain reliever for various forms of pain.

The active substance has a name identical to the name of the drug - Nimesulide. Tablets contain 100 mg. the main component and additional substances necessary to enhance the effect of the composition.

List of direct indications:

• osteoarthritis;
• dysmenorrhea;
• migraine;
• toothache;
• injuries to muscles, joints or bones;
• pathologies of the musculoskeletal system.

An analogue of Nise tablets is contraindicated in case of damage to the gastrointestinal mucosa, heart failure, and a substitute in the form of a gel is contraindicated in case of open wounds and infectious processes on the skin.

General contraindications:

• children's age (up to 12 years);
• intolerance to the components of the composition;
• blood pathologies;
• kidney/liver diseases;
• alcohol addiction;
• allergy to one or more substances from the composition of the drug.

A cheap analogue of Nise can cause side symptoms:

• pain in the epigastric region, feeling of nausea, severe heartburn, change in stool;
• constant dizziness or drowsiness;
• erythema, rash or urticaria;
• slower removal of fluid from the body, swelling;
• thrombocytopenic purpura.

The price of the drug Nimesulide is from 80 rubles.

Another cheap analogue of Nise gel and other forms of release is Ibuprofen. The drug has a wide range of effects and is recommended for providing analgesic, antipyretic, and anti-inflammatory effects.

Release form:

• tablets (extended, regular and for resorption);
• extended-release capsules;
• suspension;
• caviar gel

The active component of the analogue is ibuprofen.

Instructions for use include the following indications:

• signs of a viral disease (ARVI/flu);
• arthritis (psoriatic), osteoarthritis and spondylosis;
• migraine, myalgia and neuralgia;
• spinal artery syndrome, Barré-Lieu or nephrotic;
• bursitis, tendinitis and hematomas;
• hypotension, ankylosing spondylitis, fever;
• injury to soft tissue or bones.

An inexpensive analogue is also used for therapy for sprains of ligament tissue, arthritis (rheumatoid), articular syndrome or radiculitis.

The list of contraindications to the use of medications is extensive. The main contraindications for Ibuprofen include:

• the presence of ulcers or erosions on the walls of the stomach or intestines (except for the use of gel);
• sensitivity to the existing composition;
• pathologies of the optic nerve and deviations regarding the function of color visual perception;
• Asperin asthma;
• hypertension, amblyopia or scotoma;
• impairment of the full functioning of the kidneys/liver;
• heart failure;
• hemophilia, edema, leukopenia;
• third trimester pregnancy.

The Russian drug causes side effects that affect the nervous, digestive, circulatory and urinary systems. An allergic reaction is also possible.

The cost of medicines is from 70 rubles, depending on the form prescribed by the specialist.

An anti-inflammatory drug with an analgesic effect, Nimesil, is included in the list of drugs that are analogues of Nise.

The drug is produced only in the form of a powder for dissolution and preparation of a suspension. The active component is nimesulide.

Indications:

• infectious inflammation;
• inflammatory and degenerative processes affecting the musculoskeletal system;
• gynecological, urological and vascular inflammatory pathologies;
• post-traumatic complications;
• dental diseases;
• migraine.

Nimesil has earned positive reviews for eliminating pain during menstruation and as an antipyretic.

• inflammatory processes in the gastrointestinal tract;
• installation of a shunt in the aorta;
• fever;
• intolerance to any constituent substances.

The body’s negative reaction to the Nise analogue is expressed in the following symptoms: heart rhythm disturbances, headaches, intestinal dysfunction and allergies.

The price for Nimesil is from 500 rubles.

A good analgesic and pain reliever - Nimulid, developed on the basis of nimesulide as an active ingredient. Among the drugs that replace Nise, Nimulid is considered one of the most effective; in addition, the drug has several release forms. Lingual, regular tablets and suspension. Also, the drug in the form of an ointment can replace Nise gel.

• arthritis of rheumatoid or psoriatic nature;
• bursitis, musculoskeletal injuries;
• osteochondrosis or spondyloarthritis;
• articular gouty syndrome;
• myalgia.

Contraindications:

• erosive - ulcerative damage to the mucous membrane of the walls of the stomach or intestines;
• diseases developing in the liver or kidneys;
• tendency to allergies, including intolerance to the composition;
• pregnancy/lactation.

Side symptoms often include headaches and severe weakness. When treated with ointments, a local allergic reaction is possible.

The analogue is cheaper than Nise - from 170 rubles.

The non-steroidal drug Airtal is a substitute for Nise in three main forms (tablets, gel and suspension). However, unlike Nise, Aertal contains the main component - aceclofenac, which eliminates pain and prevents the process of inflammation.

• periarthritis in the shoulder and shoulder blade area;
• lumbago;
• rheumatism progressing in soft tissues;
• osteoarthritis;
• dental pain;
• rheumatoid arthritis;
• ankylosing spondylitis.

The cream can be used to relieve swelling of tissues and eliminate pain of a limited nature (for example, due to injuries).

Contraindications:

• damage to the walls of the gastrointestinal tract;
• hives;
• bronchospasm;
• medicinal rhinitis;
• liver dysfunction;
• circulatory pathologies;
• hyperkalemia;
• a woman carrying a fetus;
• breastfeeding;
• childhood.

Before starting treatment with Airtal, you should pay attention to signs of side effects associated with dysfunction of the stomach/intestines and nervous system. An allergic reaction is possible.

The price for Aertal is from 270 rubles.

The drug Aceclofenac with analgesic, antipyretic and anti-inflammatory effects belongs to the group of analogues of the drug Nise.

There is only one release form - tablets, which contain a medicinal substance - aceclofenac.

Indications for symptomatic therapy:

• spondylitis;
• arthritis;
• periarthritis;
• osteoarthritis;
• inflammation of soft tissues (rheumatoid).

Contraindications:

• age of patients under 18 years;
• gastrointestinal pathologies associated with the presence of ulcers or erosions;
• aortic bypass;
• heart failure;
• lactation/pregnancy;
• allergy to the medicinal composition of the drug.

Side effects manifest themselves in the digestive tract, circulatory and nervous systems, as well as in the form of allergies.

The cost of the Nise analogue is from 230 rubles.

Taking into account all the features of treatment with drugs of this group, experts are of the opinion that Nise’s analogues have more disadvantages than the original. However, it is impossible to determine what is best for the patient in each specific case. Sometimes cheaper analogues are more effective than the original drug with a high cost. The effect of drugs on the body often does not depend on price, so the choice of drugs should be trusted only to the attending physician.

For the treatment and prevention of DISEASES OF THE JOINTS and SPINE, our readers use the method of quick and non-surgical treatment recommended by leading rheumatologists in Russia, who decided to speak out against pharmaceutical lawlessness and presented a medicine that REALLY TREATS! We have become familiar with this technique and decided to bring it to your attention.

Instructions for use. Contraindications and release form.

INSTRUCTIONS
for use of the drug
NICE

Dosage forms
Gel 1%

PharmGroup
Anti-inflammatory drugs of different groups

International nonproprietary name
Nimesulide

Leave procedure
Available without a prescription

Compound
The active substance is nimesulide.

pharmachologic effect
Anti-inflammatory, antipyretic, analgesic. Selectively inhibits cyclooxygenase-2, suppresses prostaglandin synthesis at the site of inflammation. Inhibits lipid peroxidation and does not affect hemostasis and phagocytosis. After oral administration, it is well absorbed from the gastrointestinal tract. Maximum concentration is achieved after 1.5–2.5 hours. The half-life is 2-3 hours. Biotransformed in the liver. The main metabolite is the pharmacologically active hydroxynimesulide. It is excreted primarily by the kidneys. With long-term use it does not accumulate. Nise gel is a new generation non-steroidal anti-inflammatory drug (NSAID) from the sulfonamide class. It has a local analgesic and anti-inflammatory effect. When applied topically, it causes a weakening or disappearance of pain at the site of application of the gel, including pain in the joints at rest and during movement, reduces morning stiffness and swelling of the joints. Helps increase range of motion.

Indications for use
Osteoarthritis, osteoarthritis, bursitis, tendinitis, pain and inflammatory processes (in case of injuries, in the postoperative period, gynecological and infectious-inflammatory diseases). Nise gel: inflammatory and degenerative diseases of the musculoskeletal system (articular syndrome with rheumatism and exacerbation of gout, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthritis, osteochondrosis with radicular syndrome, radiculitis, inflammatory damage to the ligaments, tendons, bursitis, sciatica, lumbago) . Muscle pain of rheumatic and non-rheumatic origin. Post-traumatic inflammation of soft tissues and the musculoskeletal system (damage and rupture of ligaments, bruises).

Contraindications
Hypersensitivity, peptic ulcer of the stomach and duodenum in the acute stage, severe dysfunction of the liver and kidneys, bleeding from the gastrointestinal tract, type 2 diabetes mellitus, arterial hypertension, congestive heart failure, pregnancy, lactation. Restrictions on use: children's age (up to 12 years).

Side effect
Headache, dizziness, drowsiness; very rarely - thrombocytopenia; nausea, heartburn, stomach pain, tarry stools, melena; petechiae, purpura; oliguria; allergic reactions (exanthema, erythema, urticaria). Nise gel: Local reactions: itching, urticaria, peeling, transient change in skin color (not requiring discontinuation of the drug). If any adverse reactions occur, you should stop using the drug and consult your doctor. When applying the gel to large areas of the skin, the development of systemic adverse reactions cannot be ruled out: heartburn, nausea, vomiting, diarrhea, gastralgia, ulceration of the gastrointestinal mucosa, increased activity of “liver” transaminases; headache, dizziness; fluid retention, hematuria; allergic reactions (anaphylactic shock, skin rash); thrombocytopenia, leukopenia, anemia, agranulocytosis, prolongation of bleeding time.

Interaction
It can increase the effectiveness and toxicity of many drugs, due to their displacement from sites of binding to plasma proteins and an increase in the free fraction in the blood (with the simultaneous administration of hydantoin and sulfonamides, regular medical supervision is required). Enhances the effect of medications that reduce blood clotting; increases plasma lithium levels.

Overdose
Symptoms: increased severity of side effects. Treatment: gastric lavage, administration of activated carbon.

Directions for use and dosage
Externally. Before applying the gel, wash and dry the skin surface. Apply a uniform thin layer of gel approximately 3 cm long to the area of ​​maximum pain, without rubbing 3-4 times a day. The amount of gel and the frequency of its use (no more than 4 times a day) may vary depending on the size of the treated area and the patient’s response. The maximum dosage is 5 mg/kg/day (30 g of gel per day). Do not use the gel for more than 10 days without consulting a doctor.

special instructions
Prescribed with caution to elderly patients, with cardiovascular diseases, including arterial hypertension, bleeding tendency, disorders of the upper gastrointestinal tract, impaired renal function, during treatment with anticoagulants and antiplatelet agents. If visual disturbances occur, you should immediately stop taking the drug and consult an ophthalmologist. Patients with diabetes mellitus and patients on a low-calorie diet should take into account that the drug contains sucrose. Prescribe with caution to patients whose work requires increased attention and reaction speed.

Storage conditions
List B. At a temperature not higher than +25°C, out of the reach of children.

Manufacturers
Dr. Reddy's Laboratories Ltd (India)

The drug Nise Gel has established itself as an effective medicine that eliminates pain. In addition to the gel, tablets and oral suspension can be found in pharmacies under this brand name. The drug is prescribed for children and adults as a non-steroidal anti-inflammatory drug.

The basis for the use of Nise gel is the treatment of symptoms of inflammatory diseases of the musculoskeletal system: articular syndrome, arthritis, osteoarthritis, osteochondrosis, radiculitis, lumbago, rheumatism, etc.

Medicines are available for children from 2 years of age (in the form of a suspension). The active ingredient in nise is nimesulide. This component is able to penetrate the placental barrier and into breast milk, so it is prohibited during pregnancy and lactation.

The medicine is manufactured in India. In Russia, its prices vary between 175–470 rubles. A review of medications with nimesulide showed that among medications both Russian and imported, you can find cheap analogues of nise gel.

Russian-made analogues

Let's consider close substitutes for Nise gel among drugs from domestic manufacturers. The table offers a comparison of prices and descriptions of similar medications.

Ukrainian substitutes

Cheap analogues of the drug Nise Gel produced in Ukraine have a different active ingredient, but similar indications for use. A list of modern medicines is presented below.

• Nobi gel. The product will solve the problem of how to replace the Nice gel. Effectively relieves pain, eliminates swelling and swelling. Indications for use: pain after injuries or bruises, tenosynovitis. The average price is 120–145 rubles.
• Fort gel. An inexpensive analogue of Nice gel with the active ingredient – ​​ketoprofen. It is used topically to eliminate post-traumatic pain, sprains, and bruises. Sold as a gel in tubes of 30 and 50 g. The average price is 55–70 rubles.

Belarusian generics

Belarusian generics are an excellent option for replacing a cheap drug with nimesulide.

Other foreign analogues

Modern imported synonyms will help you choose an inexpensive analogue of Nise in tablets and other dosage forms.

• Aponil. The drug is produced in tablets. It is used to treat pain, reduce temperature, and for inflammatory processes of the musculoskeletal system. Country of origin: Cyprus. The average price is 110–130 rubles.
• Nimesil. The best imported analogue of Nise with a similar effect. The basis of the medicine is nimesulide. Release form: powder for preparing a drink, which is consumed orally. The drug is produced in Italy and Germany. The average price is 25–690 rubles.
• Nimulid. Non-steroidal anti-inflammatory drug with antipyretic and analgesic function. Available in the form of tablets, gel, suspension. Country of origin: India. The average price is 130–355 rubles.
• Nimika. Instant tablets. Indications for use: osteoarthritis, diseases of rheumatic origin, postoperative pain. Fever, dysmenorrhea. The drug is produced in India. The average price is 120–250 rubles.

The anti-inflammatory, analgesic and antipyretic properties of nimesulides make them popular in the group of non-steroidal drugs. They perform an antioxidant function and perfectly relieve pain in a short time. All this, as well as the reasonable cost, forces patients to purchase such drugs without medical advice.

This approach to choosing an anesthetic drug is unacceptable due to the presence of a wide range of contraindications. Children and patients with heart failure, kidney disease, diabetes mellitus and arterial hypertension need to be monitored by a doctor for a possible reaction to the drug.

Related Posts

Good day everyone.

Nise tablets are known to almost everyone. But not everyone knows that this popular drug has analogues, they are cheaper, and the active ingredient is the same.

True, cheap analogues do not always help as well as the drug itself. However, in my case, Nimesulide turned out to be very effective.

So, let's get acquainted with the drug.

Price-77.50 rubles

Quantity -20 tablets \100 mg

Manufacturer: Ozone LLC. Russia

Active ingredient: Nimesulide

By the way, please note that the active ingredient in the drug Nise is also Nimesulide

But the price of these drugs is different. Nise costs from 180 rubles, Nimesulide no more than 80 rubles. That is, there is a difference.

Pharmacological properties:

Nimesulide is a drug from the group of non-steroidal anti-inflammatory drugs. It has anti-inflammatory, analgesic and antipyretic effects.

I would especially like to note that the drug is also anti-inflammatory, this is important for me.

The pack contains 2 blisters of 10 tablets each and instructions for use.

The tablets are not large in size, the color is light yellow. The tablets taste bitter, it is recommended to take them with plenty of water. Children under 12 years of age cannot take them, so this is not critical. Adults are able to swallow a bitter tablet. In principle, if you swallow it quickly, you may not even feel the bitterness.

This drug has an extensive list of indications, that is, tablets can help in many cases.

Indications for use:

• rheumatoid arthritis
• articular syndrome during exacerbation of gout
• psoriatic arthritis
• ankylosing spondylitis
• Steochondrosis with radicular syndrome, osteoarthritis
• myalgia of rheumatic and non-rheumatic origin
• inflammation of ligaments, tendons, bursitis, pain of various origins (including in the postoperative period, with injuries, toothache, headache, arthralgia, lumboischialgia).

However, the list of contraindications and side effects is also long. So you should not get carried away with the drug.

Now my case.

I rarely treat my teeth on time. I had a toothache, I muffled the pain with pills, and I continue to walk. I usually take Ketorol, which has always helped me a lot.

But, at one “wonderful” moment, the tooth hurt so much that you could even climb the wall. I took a Ketorol tablet, no effect. A little later I took more, and again it didn’t work. It’s evening time, you can’t rush to treat the tooth.

I had to urgently go to the pharmacy and ask for something more effective. They recommended Nimesulide. I bought it, immediately took the pill, and the pain began to subside.

Anyone who has experienced a very severe toothache understands what happiness it is when it goes away. I fell asleep peacefully.

But by morning a new “surprise” awaited me: gumboil appeared.

In general, my tooth was removed, my gums were cut, and again I was prescribed Ketorol. But, I had Nimesulide. And when the injection began to go away and the pain grew, I took Nimesulide again. And everything became fine.

But, we must remember that even an adult cannot take more than 2 tablets a day! You should not get carried away with the drug under any circumstances, no matter how well it helps, the course should last a minimum number of days.

I didn’t experience any side effects. In addition, when my joints only ache slightly and don’t hurt a lot, I prefer not to take any pills, but just endure it.

But while I was “fighting” with the tooth, my joints stopped hurting completely. And this is also the merit of Nimesulide.

Looking at my torment and the quick relief from it, my husband was very impressed and bought a pack of Nimesulide for himself. He has phantom pains. But so far he hasn’t had to use it.

I didn’t consult a doctor, I just felt really hot and had to use the drug.

For the rest of you, I would like to remind you consult your doctor before using the drug.

Because there are still a lot of side effects and contraindications.

Here she is, my little savior.

Aponil is an inexpensive analogue of Nise in tablets. Nise has several forms of release, gel and tablets are always popular. But many people cannot afford the prices for these medications. The price of Aponil is an order of magnitude less than that of Nise gel, and the results from taking it are no worse.

By their nature, both Aponil and Nise are symptomatic medications that do not provide any progress in the treatment of the disease, but only temporarily alleviate the condition of the victim. For serious illnesses, using these medications alone will not be enough.

Composition of the drug

Aponil contains the active substance nimesulide. The Nise analogue reduces inflammation, has antipyretic and analgesic effects. Produced by the factories of Melokemi LTD, known for its quality products. The medicine has proven itself in many countries as an inexpensive and effective pain reliever.

When to and when not to take the drug

Doctors of various specialties can prescribe Apanol; most often this prescription is given by gynecologists, rheumatologists and neurologists. Indications for use:

• rheumatic diseases;
• postoperative pain;
• pain after injury;
• headache and toothache;
• fever;
• inflammatory diseases of bones and joints.

The examination and test data reveal contraindications that patients may not be aware of. According to the instructions, you cannot use Aponil in the following cases:

• gastrointestinal ulcers;
• bleeding of the stomach and intestines;
• aspirin bronchial asthma
• significant impairment of the kidneys and liver;
• pregnancy;
• childhood.

Hypersensitivity to the components of the medication is observed in extremely rare cases and manifests itself in the form of vomiting, allergies, and lack of results from taking it.

Directions for use and doses

Aponil is available in tablets. The package contains 20 tablets of 100.0 mg. Doses for use in adults range from 50.0 mg to 200.0 mg, as determined by the doctor. As practice shows, the average dose is 100.0 mg, that is, 1 tablet. The maximum dose per day is 400.0 mg, that is, 4 tablets.

The medicine is taken 2 times a day after meals, the tablets should be washed down with water. It is important not to forget that the dosage recommended in the instructions cannot be exceeded. Reviews say that side effects are most often encountered by those people who abuse painkillers. The occurrence of side effects is indicated by:

• drowsiness;
• headache;
• nausea and vomiting;
• heartburn;
• diarrhea;
• hematuria;
• oliguria;
• thrombocytopenia;
• leukopenia;
• anemia;
• as well as various allergic reactions.

Possible effects in case of overdose: nausea and vomiting. It is treated by gastric lavage and the administration of adsorbents.

Release forms and existing analogues

Painkillers of this kind with a wide spectrum of action are always in demand among patients. In addition to Aponil, Nise has several more widely known analogues:

1. Nimulid. There is both ointment and tablets. The active substance contained in it is nimesulide.
2. Nimesulide is an almost complete analogue of the drugs Aponil and Nise, a gel for external use.

Aponil has become so popular because of its fast action and low price, but if this medicine is not available in the pharmacy, you can use analogues.

Patient reviews

I have pinched nerves in my hip joint and it hurts to stand. I didn't find Gel Nise. Found Aponil. I began to walk without lameness and stand without pain. The only side effect that appeared was a headache on the day of administration.

Dmitry Neuronov, 40 years old.

I was prescribed Aponil for inflammation of the wrist joint. For some reason I vomited after it. I thought I was poisoned, and the doctor said that there could be such a strong response to this medicine. Be careful, if anything happens, consult a doctor.

Svetlana Cherkasskaya, 38 years old.